Sandra L. Pfister, PhD

Interim Director, Clinical Learning Environment Pillar; Member, Faculty Pillar, Kern Institute

Locations

Kern Institute
8701 Watertown Plank Rd., Suite M1990
Milwaukee, WI 53226

Contact Information

Biography

Academic Appointments/Other Titles

Professor, Pharmacology and Toxicology

Dr. Pfister contributes to the assessment of the state of the faculty on issues of well-being and burnout with overall goal to develop and implement effective strategies for improved well-being. Additionally, she has a role in providing input to initiatives designed to advance women’s leadership and development based on her prior leadership of the Council for Women’s Advocacy.

View Department Profile

Leadership Positions

Chair Emeritus, Council for Women's Advocacy
Course Director, M2 Cardiovascular Unit
Course Director, Principles of Drug Action
Member Faculty Pillar, Kern Institute
Vice-President, Faculty Council

Macrophage 12(S)-HETE Enhances Angiotensin II-Induced Contraction by a BLT2 (Leukotriene B4 Type-2 Receptor) and TP (Thromboxane Receptor)-Mediated Mechanism in Murine Arteries.

(Kriska T, Herrnreiter A, Pfister SL, Adebesin A, Falck JR, Campbell WB.) Hypertension. 2022 Jan;79(1):104-114 PMID: 34784723 PMCID: PMC8849474 SCOPUS ID: 2-s2.0-85120936681 11/18/2021
GPR40 is a low-affinity epoxyeicosatrienoic acid receptor in vascular cells.

(Park SK, Herrnreiter A, Pfister SL, Gauthier KM, Falck BA, Falck JR, Campbell WB.) J Biol Chem. 2018 Jul 06;293(27):10675-10691 PMID: 29777058 PMCID: PMC6036206 SCOPUS ID: 2-s2.0-85049468178 05/20/2018
(5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid: A stable isomer of 15(S)-HETE that retains key vasoconstrictive and antiproliferative activity.

(Pfister SL, Klimko PG, Conrow RE.) Prostaglandins Other Lipid Mediat. 2016 Mar;123:33-9 PMID: 27117058 PMCID: PMC4893888 SCOPUS ID: 2-s2.0-84969584659 04/28/2016
Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER).

(Ma S, Yin N, Qi X, Pfister SL, Zhang MJ, Ma R, Chen G.) Oncotarget. 2015 May 30;6(15):13320-33 PMID: 26079946 PMCID: PMC4537017 SCOPUS ID: 2-s2.0-84931073824 06/17/2015
Endothelial 12(S)-HETE vasorelaxation is mediated by thromboxane receptor inhibition in mouse mesenteric arteries.

(Siangjong L, Gauthier KM, Pfister SL, Smyth EM, Campbell WB.) Am J Physiol Heart Circ Physiol. 2013 Feb 01;304(3):H382-92 PMID: 23203967 PMCID: PMC3774504 SCOPUS ID: 2-s2.0-84873319463 12/04/2012
Pulmonary arterial responses to reactive oxygen species are altered in newborn piglets with chronic hypoxia-induced pulmonary hypertension.

(Fike CD, Aschner JL, Slaughter JC, Kaplowitz MR, Zhang Y, Pfister SL.) Pediatr Res. 2011 Aug;70(2):136-41 PMID: 21516056 PMCID: PMC3131458 04/26/2011
Role of superoxide and thromboxane receptors in acute angiotensin II-induced vasoconstriction of rabbit vessels.

(Pfister SL, Nithipatikom K, Campbell WB.) Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2064-71 PMID: 21460202 PMCID: PMC3119100 SCOPUS ID: 2-s2.0-79958028562 04/05/2011
Role of lipoxygenase metabolites of arachidonic acid in enhanced pulmonary artery contractions of female rabbits.

(Pfister SL.) Hypertension. 2011 Apr;57(4):825-32 PMID: 21300669 PMCID: PMC3073701 SCOPUS ID: 2-s2.0-79953224393 02/09/2011
Mechanisms underlying increased reactivity of pulmonary arteries contralateral to a localized high-flow anastomosis.

(Pfister S, Somberg L, Lowry T, Gao Y, Medhora M, Jacobs ER.) J Thorac Cardiovasc Surg. 2011 Feb;141(2):425-31 PMID: 21075383 PMCID: PMC3052931 SCOPUS ID: 2-s2.0-78751601116 11/16/2010
Protein complex formation with heat shock protein 90 in chronic hypoxia-induced pulmonary hypertension in newborn piglets.

(Fike CD, Pfister SL, Slaughter JC, Kaplowitz MR, Zhang Y, Zeng H, Frye NR, Aschner JL.) Am J Physiol Heart Circ Physiol. 2010 Oct;299(4):H1190-204 PMID: 20693398 PMCID: PMC2957352 SCOPUS ID: 2-s2.0-77958025198 08/10/2010
Vascular pharmacology of epoxyeicosatrienoic acids.

(Pfister SL, Gauthier KM, Campbell WB.) Adv Pharmacol. 2010;60:27-59 PMID: 21081214 PMCID: PMC3373307 SCOPUS ID: 2-s2.0-78349236168 11/18/2010
Chronic hypoxia enhances 15-lipoxygenase-mediated vasorelaxation in rabbit arteries.

(Aggarwal NT, Pfister SL, Gauthier KM, Chawengsub Y, Baker JE, Campbell WB.) Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H678-88 PMID: 19112096 PMCID: PMC2660232 SCOPUS ID: 2-s2.0-64049085636 12/30/2008