Research Bench Lab

McNally Laboratory

Location

Microbiology & Immunology

BSB B2235

General Interests

RNA Processing (splicing and polyadenylation) in Cells and Viruses

View Mark T. McNally Bio
Mark McNally Laboratory
Backlit DNA sequence and sample

Research Areas

My laboratory uses molecular, genetic, biochemical, and cell biological approaches to study post-transcriptional mechanisms of gene regulation, including RNA splicing and polyadenylation control. One area of focus uses the simple retrovirus, Rous sarcoma virus (RSV), to understand the role of RNA processing in the virus life cycle. We are also exploiting antisense oligonucleotide technologies to alter RNA splicing as an approach to develop a breast cancer therapeutic.

Recent Publications