Research Bench Lab

McNally Laboratory


Microbiology & Immunology

BSB B2235

General Interests

RNA Processing (splicing and polyadenylation) in Cells and Viruses

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Mark McNally Laboratory
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Research Areas

My laboratory uses molecular, genetic, biochemical, and cell biological approaches to study post-transcriptional mechanisms of gene regulation, including RNA splicing and polyadenylation control. One area of focus uses the simple retrovirus, Rous sarcoma virus (RSV), to understand the role of RNA processing in the virus life cycle. We are also exploiting antisense oligonucleotide technologies to alter RNA splicing as an approach to develop a breast cancer therapeutic.

Recent Publications