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Paul E. Barkhaus, MD

Professor

Locations

  • Froedtert Hospital
  • Zablocki VA Medical Center
  • Children's Wisconsin - Milwaukee
  • Froedtert Menomonee Falls Hospital
  • Neuroscience Institute – Specialty Clinics
  • Zablocki VA Medical Center
  • Hand Center Clinic - Tosa Health Center

Specialties

  • Neurology

Languages

  • English

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Established Patients: Hand Center

Education

  • MD - Doctor of Medicine

Biography

Appointments

Professor, Physical Medicine and Rehabilitation

Director, Amyotrophic Lateral Sclerosis Program (ALS Association Certified Center of Excellence)

Specialty

Adult Neurology

Subspecialties

Amyotrophic Lateral Sclerosis
Electromyography
Neuromuscular Disease

Training

Resident, Department of Neurology, Wayne State University, Detroit, Michigan, 1975-1978

Electromyography Fellowship, Department of Neurology, University of Minnesota, Minneapolis, Minnesota, 1978-1979

Clinical Neuromuscular Diseases Fellowship, Department of Neurology, University of Arizona, Tucson, Arizona, 1979-1980

Single Fiber Electromyography, Uppsala University, Uppsala, Sweden, 1980

Visiting Scientist, November, Department of Clinical Neurophysiology Uppsala University, Uppsala, Sweden, 1985-1986

Senior Research Fellowship in Electromyography, Duke University Medical Center, Durham, North Carolina, 1986-1987

Societies

American Academy of Neurology (Fellow)
American Neurological Association
American Association of Electromyography and Electrodiagnosis (Fellow)
Wisconsin Neurological Society (Past President, 2000-2001)

Clinical Interests

Amyotrophic Lateral Sclerosis

Quantitative Electromyography

View Faculty Collaboration Database profile

Honors and Awards

Distinguished Service Award, Wayne State University School of Medicine, 1975
Trainee Award, Federation of Western Societies of Neurological Sciences, 1980
Special Commendation, Minnesota Chapter, Myasthenia Gravis Foundation, 1983
Special Commendation, Cincinnati Chapter, Muscular Dystrophy Association, 1983
Alumnus Hall of Fame, Allen Park High School, Allen Park, Michigan, 1987
Distinguished Visitor to USS Theodore Roosevelt, by invitation of Commander, U.S. 2nd Fleet, 2000
Clinical Neurophysiology Teacher of The Year, Department of Neurology, Medical College of Wisconsin, 2001 and 2010
Selected for inclusion to "America's Top Physicians", Consumers' Research Council of America, 2006
Elected to Active Membership, American Neurological Association
Selected for inclusion in "Best Doctors®" (2005- )
Special Commendation by Paralyzed Veterans of America for Advocacy in Veterans with ALS, 2010

Research Interests

Drug Trials in Patients with ALS (one active)

Motor Unit Number Indexing

Compound Muscle Action Potentials

Publications

  • Volume conduction: Extracellular waveform generation in theory and practice.

    (Dumitru D, Nandedkar SD, Barkhaus PE.) Muscle Nerve. 2023 Jun;67(6):439-455 PMID: 36815566 SCOPUS ID: 2-s2.0-85149317026 02/24/2023

  • ALSUntangled #65: glucocorticoid corticosteroids.

    (Goslinga JA, Terrelonge M Jr, Bedlack R, Barkhaus P, Barnes B, Bertorini T, Bromberg M, Carter G, Chen A, Crayle J, Dimachkie M, Jiang L, Levitsky G, Lund I, Martin S, Mcdermott C, Pattee G, Pierce K, Ratner D, Slachtova L, Sun Y, Wicks P.) Amyotroph Lateral Scler Frontotemporal Degener. 2023 May;24(3-4):351-357 PMID: 35997522 SCOPUS ID: 2-s2.0-85136863606 08/24/2022

  • Defective E2 electrode lead gives low-amplitude compound muscle action potential.

    (Nandedkar SD, Barkhaus PE.) Muscle Nerve. 2023 Apr;67(4):310-314 PMID: 36605021 SCOPUS ID: 2-s2.0-85146933119 01/07/2023

  • ALSUntangled #63: ketogenic diets.

    (Bedlack R, Barkhaus PE, Barnes B, Beauchamp M, Bertorini T, Bromberg MB, Carter GT, Chaudry V, Cudkowicz M, Jackson C, Levitsky G, Lund I, McDermott C, Novella S, Olby N, Ostrow L, Pattee GL, Heiman-Patterson T, Ratner D, Salmon K, Steves S, Terrelonge M, Wicks P, Wills AM.) Amyotroph Lateral Scler Frontotemporal Degener. 2023 Feb;24(1-2):159-163 PMID: 34645313 SCOPUS ID: 2-s2.0-85117201496 10/15/2021

  • ALSUntangled # 69: astaxanthin.

    (Fullam T, Armon C, Barkhaus P, Barnes B, Beauchamp M, Benatar M, Bertorini T, Bowser R, Bromberg M, Mascias Cadavid J, Carter GT, Dimachkie M, Ennist D, Feldman EL, Heiman-Patterson T, Jhooty S, Lund I, Mcdermott C, Pattee G, Ratner D, Wicks P, Bedlack R.) Amyotroph Lateral Scler Frontotemporal Degener. 2023 Jan 24:1-5 PMID: 36694292 SCOPUS ID: 2-s2.0-85147227592 01/26/2023

  • Motor unit recruitment and firing rate at low force of contraction.

    (Nandedkar SD, Barkhaus PE, Stålberg EV.) Muscle Nerve. 2022 Dec;66(6):750-756 PMID: 36214178 SCOPUS ID: 2-s2.0-85140235887 10/11/2022

  • ALSUntangled #67: rituximab.

    (Li X, Armon C, Barkhaus P, Barnes B, Benatar M, Bertorini T, Bromberg M, Carter GT, Crayle J, Cudkowicz M, Dimachkie M, Feldman EL, Glass J, Goslinga J, Heiman-Patterson T, Jhooty S, Lichtenstein R, Lund I, Mcdermott C, Pattee G, Pierce K, Ratner D, Salmon K, Wicks P, Bedlack R.) Amyotroph Lateral Scler Frontotemporal Degener. 2022 Sep 15:1-4 PMID: 36106861 SCOPUS ID: 2-s2.0-85138163435 09/16/2022

  • ALSUntangled #66: antimycobacterial antibiotics.

    (Pierce ES, Barkhaus P, Beauchamp M, Bromberg M, Carter GT, Goslinga J, Greeley D, Kihuwa-Mani S, Levitsky G, Lund I, McDermott C, Pattee G, Pierce K, Polak M, Ratner D, Wicks P, Bedlack R.) Amyotroph Lateral Scler Frontotemporal Degener. 2022 Aug 01:1-5 PMID: 35913017 SCOPUS ID: 2-s2.0-85135321204 08/02/2022

  • ALSUntangled #62: vitamin C.

    (Bedlack R, Barkhaus P, Carter G, Crayle J, Mcdermott C, Pattee G, Polak M, Salmon K, Wicks P.) Amyotroph Lateral Scler Frontotemporal Degener. 2022 Aug;23(5-6):476-479 PMID: 34187257 SCOPUS ID: 2-s2.0-85134444415 07/01/2021

  • Analysis of the compound muscle action potential scan: Step index (STEPIX) and amplitude index (AMPIX).

    (Nandedkar SD, Barkhaus PE, Stålberg EV.) Clin Neurophysiol. 2022 Jul;139:119-127 PMID: 35537985 SCOPUS ID: 2-s2.0-85129776613 05/11/2022

  • Reinnervation as measured by the motor unit size index is associated with preservation of muscle strength in amyotrophic lateral sclerosis, but not all muscles reinnervate.

    (Chan Y, Alix JJP, Neuwirth C, Barkhaus PE, Castro J, Jenkins TM, McDermott CJ, Shaw PJ, de Carvalho M, Nandedkar S, Stålberg E, Weber M.) Muscle Nerve. 2022 Feb;65(2):203-210 PMID: 34687220 SCOPUS ID: 2-s2.0-85118900304 10/24/2021

  • ALSUntangled #60: light therapy

    (Bedlack R, Barkhaus P, Barnes B, Bereman M, Bertorini T, Carter G, Crayle J, Kihuwa-Mani S, Bowser R, Kittrell P, McDermott C, Pattee G, Salmon K, Wicks P.) Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2022;23(3-4):315-319 SCOPUS ID: 2-s2.0-85102183606 01/01/2022