Matthew D. Budde, PhD

Associate Professor

Locations

Neurosurgery
8701 Watertown Plank Rd.
Milwaukee, WI 53226

Education

Postdoctoral Fellow, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 2011
PhD, Neuroscience, Washington University, St Louis, MO, 2008
BS, Psychology, University of Wisconsin-Madison, WI, 2001

Biography

Dr. Matthew Budde is an associate professor of neurosurgery at the Medical College of Wisconsin. He received his PhD in Neuroscience from Washington University in St. Louis in 2008. He completed his postdoctoral training at the National Institutes of Health in Bethesda, MD and was a recipient of the Fellows Award for Research Excellence in 2011.

Dr. Budde’s primary research interest is to develop and employ magnetic resonance imaging techniques to diagnosis and monitor injuries and diseases of the central nervous system. He has made significant contributions to the field and has over 20 peer-reviewed publications. He is an active member and Junior Fellow of the International Society for Magnetic Resonance in Medicine and a member of the Society for Neuroscience.

Honors and Awards

05/2006 – Young Investigator Award Finalist, International Society for Magnetic Resonance in Medicine
05/2010 – Junior Fellow Recipient, International Society for Magnetic Resonance in Medicine
02/2011 – Fellows Award for Research Excellence (FARE), National Institutes of Health, Bethesda, National Institutes of Health

Research Experience

Brain Concussion
Brain Injuries
Diffuse Axonal Injury
Diffusion Magnetic Resonance Imaging
Diffusion Tensor Imaging
Disease Models, Animal
Histology
Hypoxia-Ischemia, Brain
Magnetic Resonance Imaging
Microscopy
Multiple Sclerosis
Neurosciences

MCW Program / Core Facilities

Center for Imaging Research
Neuroscience Research Center

Research Interests

Development and application of magnetic resonance imaging techniques to diagnose and monitor brain and spinal cord injury.

Apply advanced MRI techniques, including diffusion tensor imaging (DTI), to detect and monitor injury to the central nervous system noninvasively
Define the specific biological features that give rise to the MRI findings using animal models of neurological injury
Determine the prognostic capabilities of MRI in acute brain and spinal cord trauma

Acute Magnetic Resonance Imaging Predictors of Chronic Motor Function and Tissue Sparing in Rat Cervical Spinal Cord Injury.

(Lee SY, Schmit BD, Kurpad SN, Budde MD.) J Neurotrauma. 2022 Aug 30 PMID: 35708112 06/17/2022
Repeated blast mild traumatic brain injury and oxycodone self-administration produce interactive effects on neuroimaging outcomes.

(Muelbl MJ, Glaeser BL, Shah AS, Chiariello RA, Nawarawong NN, Stemper BD, Budde MD, Olsen CM.) Addict Biol. 2022 03;27(2):e13134 PMID: 35229952 PMCID: PMC8896287 SCOPUS ID: 2-s2.0-85125380733 03/02/2022
A Preclinical Rodent Model for Repetitive Subconcussive Head Impact Exposure in Contact Sport Athletes.

(Stemper BD, Shah A, Chiariello R, McCarthy C, Jessen K, Sarka B, Seifert J, Budde MD, Wang K, Olsen CM, McCrea M.) Front Behav Neurosci. 2022;16:805124 PMID: 35368301 PMCID: PMC8965565 SCOPUS ID: 2-s2.0-85127445249 04/05/2022
Stay on the Beat With Tensor-Valued Encoding: Time-Dependent Diffusion and Cell Size Estimation in ex vivo Heart

(LasiA? S, Yuldasheva N, Szczepankiewicz F, Nilsson M, Budde M, Dalla??Armellina E, Schneider JE, Teh I, Lundell H.) Frontiers in Physics. 25 March 2022;10 SCOPUS ID: 2-s2.0-85128351623 03/25/2022
Filtered Diffusion-Weighted MRI of the Human Cervical Spinal Cord: Feasibility and Application to Traumatic Spinal Cord Injury.

(Murphy SA, Furger R, Kurpad SN, Arpinar VE, Nencka A, Koch K, Budde MD.) AJNR Am J Neuroradiol. 2021 11;42(11):2101-2106 PMID: 34620590 PMCID: PMC8583257 SCOPUS ID: 2-s2.0-85119420507 10/09/2021
Generic acquisition protocol for quantitative MRI of the spinal cord.

(Cohen-Adad J, Alonso-Ortiz E, Abramovic M, Arneitz C, Atcheson N, Barlow L, Barry RL, Barth M, Battiston M, B??chel C, Budde M, Callot V, Combes AJE, De Leener B, Descoteaux M, de Sousa PL, Dost?!l M, Doyon J, Dvorak A, Eippert F, Epperson KR, Epperson KS, Freund P, Finsterbusch J, Foias A, Fratini M, Fukunaga I, Wheeler-Kingshott CAMG, Germani G, Gilbert G, Giove F, Gros C, Grussu F, Hagiwara A, Henry PG, Hor?!k T, Hori M, Joers J, Kamiya K, Karbasforoushan H, Ke??kovsk?? M, Khatibi A, Kim JW, Kinany N, Kitzler H, Kolind S, Kong Y, KudliA?ka P, Kuntke P, Kurniawan ND, Kusmia S, Labounek R, Lagan? MM, Laule C, Law CS, Lenglet C, Leutritz T, Liu Y, Llufriu S, Mackey S, Martinez-Heras E, Mattera L, Nestrasil I, O'Grady KP, Papinutto N, Papp D, Pareto D, Parrish TB, Pichiecchio A, Prados F, Rovira ??, Ruitenberg MJ, Samson RS, Savini G, Seif M, Seifert AC, Smith AK, Smith SA, Smith ZA, Solana E, Suzuki Y, Tackley G, Tinnermann A, Valo?!ek J, Van De Ville D, Yiannakas MC, Weber KA 2nd, Weiskopf N, Wise RG, Wyss PO, Xu J.) Nat Protoc. 2021 10;16(10):4611-4632 PMID: 34400839 PMCID: PMC8811488 SCOPUS ID: 2-s2.0-85112706163 08/18/2021
Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers.

(Cohen-Adad J, Alonso-Ortiz E, Abramovic M, Arneitz C, Atcheson N, Barlow L, Barry RL, Barth M, Battiston M, B??chel C, Budde M, Callot V, Combes AJE, De Leener B, Descoteaux M, de Sousa PL, Dost?!l M, Doyon J, Dvorak A, Eippert F, Epperson KR, Epperson KS, Freund P, Finsterbusch J, Foias A, Fratini M, Fukunaga I, Gandini Wheeler-Kingshott CAM, Germani G, Gilbert G, Giove F, Gros C, Grussu F, Hagiwara A, Henry PG, Hor?!k T, Hori M, Joers J, Kamiya K, Karbasforoushan H, Ke??kovsk?? M, Khatibi A, Kim JW, Kinany N, Kitzler HH, Kolind S, Kong Y, KudliA?ka P, Kuntke P, Kurniawan ND, Kusmia S, Labounek R, Lagan? MM, Laule C, Law CS, Lenglet C, Leutritz T, Liu Y, Llufriu S, Mackey S, Martinez-Heras E, Mattera L, Nestrasil I, O'Grady KP, Papinutto N, Papp D, Pareto D, Parrish TB, Pichiecchio A, Prados F, Rovira ??, Ruitenberg MJ, Samson RS, Savini G, Seif M, Seifert AC, Smith AK, Smith SA, Smith ZA, Solana E, Suzuki Y, Tackley G, Tinnermann A, Valo?!ek J, Van De Ville D, Yiannakas MC, Weber Ii KA, Weiskopf N, Wise RG, Wyss PO, Xu J.) Sci Data. 2021 08 16;8(1):219 PMID: 34400655 PMCID: PMC8368310 SCOPUS ID: 2-s2.0-85112695767 08/18/2021
Diffusion-prepared fast spin echo for artifact-free spinal cord imaging.

(Lee SY, Meyer BP, Kurpad SN, Budde MD.) Magn Reson Med. 2021 08;86(2):984-994 PMID: 33720450 PMCID: PMC8369385 SCOPUS ID: 2-s2.0-85102478269 03/16/2021
Optimized cervical spinal cord perfusion MRI after traumatic injury in the rat.

(Meyer BP, Hirschler L, Lee S, Kurpad SN, Warnking JM, Barbier EL, Budde MD.) J Cereb Blood Flow Metab. 2021 08;41(8):2010-2025 PMID: 33509036 PMCID: PMC8327111 SCOPUS ID: 2-s2.0-85100579355 01/30/2021
Diagnostic Imaging in Spinal Cord Injury.

(Shabani S, Meyer BP, Budde MD, Wang MC.) Neurosurg Clin N Am. 2021 Jul;32(3):323-331 PMID: 34053720 SCOPUS ID: 2-s2.0-85105493933 06/01/2021
Relationships between spinal cord blood flow measured with flow-sensitive alternating inversion recovery (FAIR) and neurobehavioral outcomes in rat spinal cord injury.

(Lee S, Wilkins N, Schmit BD, Kurpad SN, Budde MD.) Magn Reson Imaging. 2021 05;78:42-51 PMID: 33556483 PMCID: PMC8501290 SCOPUS ID: 2-s2.0-85100974870 02/09/2021
Test-retest reproducibility of in vivo oscillating gradient and microscopic anisotropy diffusion MRI in mice at 9.4 Tesla.

(Rahman N, Xu K, Omer M, Budde MD, Brown A, Baron CA.) PLoS One. 2021;16(11):e0255711 PMID: 34739479 PMCID: PMC8570471 SCOPUS ID: 2-s2.0-85118976558 11/06/2021

Neurosurgery