Sunila Pradeep, PhD

Publications

• Epigenetic modulation of BARD1 to enhance anti-VEGF therapy.

  (Bayraktar E, Rodriguez-Aguayo C, Stur E, Kumar S, Mangala LS, Jennings NB, Bayram NN, Corvigno S, Asare A, Ivan C, Kim MS, Vu TC, Hanjra P, Kim S, Ahumada AL, Wu W, Lee S, Szymanowska A, Oztatlici H, Estecio MR, Lee JS, Jain AK, Sahni N, Hagan JP, Baylin S, Liu J, Lopez-Berestein G, Pradeep S, Sood AK.) Cell Rep Med. 2025 Sep 16;6(9):102329 PMID: 40907495 PMCID: PMC12490209 SCOPUS ID: 2-s2.0-105015794174 09/05/2025

• eIF4E Enriched Extracellular Vesicles Induce Immunosuppressive Macrophages through HMGCR-Mediated Metabolic Rewiring.

  (Mittal S, Nenwani M, Pulikkal Kadamberi I, Kumar S, Animasahun O, George J, Tsaih SW, Gupta P, Singh M, Geethadevi A, Dey C, Meurs N, Shankaran A, Chaluvally Raghavan P, Nagrath D, Pradeep S.) Adv Sci (Weinh). 2025 Aug 18:e06307 PMID: 40820860 SCOPUS ID: 2-s2.0-105013566484 08/18/2025

• Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): the interplay of gut microbiome, insulin resistance, and diabetes

  (Dua A, Kumari R, Singh M, Kumar R, Pradeep S, Ojesina AI, Kumar R.) Frontiers in Medicine. 2025;12 SCOPUS ID: 2-s2.0-105014515937 01/01/2025

• Blocking Oncostatin M receptor abrogates STAT3 mediated integrin signaling and overcomes chemoresistance in ovarian cancer.

  (Geethadevi A, Ku Z, Tsaih SW, Parashar D, Kadamberi IP, Xiong W, Deng H, George J, Kumar S, Mittal S, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P.) NPJ Precis Oncol. 2024 Jun 05;8(1):127 PMID: 38839865 PMCID: PMC11153533 SCOPUS ID: 2-s2.0-85195471255 06/06/2024

• From Gut to Hormones: Unraveling the Role of Gut Microbiota in (Phyto)Estrogen Modulation in Health and Disease.

  (Kumari N, Kumari R, Dua A, Singh M, Kumar R, Singh P, Duyar-Ayerdi S, Pradeep S, Ojesina AI, Kumar R.) Mol Nutr Food Res. 2024 Mar;68(6):e2300688 PMID: 38342595 SCOPUS ID: 2-s2.0-85184482849 02/12/2024

• Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model

  (Mittal S, Kumar S, Gupta P, Singh M, Chaluvally-Raghavan P, Pradeep S.) STAR Protocols. 21 June 2024;5(2) SCOPUS ID: 2-s2.0-85187377383 06/21/2024

• Preclinical activity of selinexor in combination with eribulin in uterine leiomyosarcoma.

  (Mittal S, Kadamberi IP, Chang H, Wang F, Kumar S, Tsaih SW, Walker CJ, Chaluvally-Raghavan P, Charlson J, Landesman Y, Pradeep S.) Exp Hematol Oncol. 2023 Sep 15;12(1):78 PMID: 37715291 PMCID: PMC10503035 SCOPUS ID: 2-s2.0-85171339411 09/16/2023

• Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L.

  (LaFargue CJ, Amero P, Noh K, Mangala LS, Wen Y, Bayraktar E, Umamaheswaran S, Stur E, Dasari SK, Ivan C, Pradeep S, Yoo W, Lu C, Jennings NB, Vathipadiekal V, Hu W, Chelariu-Raicu A, Ku Z, Deng H, Xiong W, Choi HJ, Hu M, Kiyama T, Mao CA, Ali-Fehmi R, Birrer MJ, Liu J, Zhang N, Lopez-Berestein G, de Franciscis V, An Z, Sood AK.) Nat Commun. 2023 Apr 26;14(1):2407 PMID: 37100807 PMCID: PMC10133315 SCOPUS ID: 2-s2.0-85153918496 04/27/2023

• RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.

  (George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P.) Cell Rep. 2023 Mar 28;42(3):112228 PMID: 36884347 PMCID: PMC10233815 SCOPUS ID: 2-s2.0-85149682952 03/09/2023

• Metabolic Reprogramming in Tumor-Associated Macrophages in the Ovarian Tumor Microenvironment.

  (Kumar S, Mittal S, Gupta P, Singh M, Chaluvally-Raghavan P, Pradeep S.) Cancers (Basel). 2022 Oct 25;14(21) PMID: 36358644 PMCID: PMC9656653 SCOPUS ID: 2-s2.0-85141848301 11/12/2022

• Author Correction: Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.

  (Zheng Y, Sethi R, Mangala LS, Taylor C, Goldsmith J, Wang M, Masuda K, Carrami EM, Mannion D, Miranda F, Herrero-Gonzalez S, Hellner K, Chen F, Alsaadi A, Albukhari A, Fotso DC, Yau C, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Knapp S, Gray NS, Campo L, Myers KA, Dhar S, Ferguson D, Bast RC Jr, Sood AK, von Delft F, Ahmed AA.) Nat Commun. 2022 Jun 10;13(1):3352 PMID: 35688808 PMCID: PMC9187678 SCOPUS ID: 2-s2.0-85131828825 06/11/2022

• Extracellular vesicle contents as non-invasive biomarkers in ovarian malignancies

  (McAlarnen LA, Gupta P, Singh R, Pradeep S, Chaluvally-Raghavan P.) Molecular Therapy Oncolytics. 15 September 2022;26:347-359 SCOPUS ID: 2-s2.0-85136664501 09/15/2022