Paula E North, MD, PhD | Medical College of Wisconsin

Paula E. North, MD, PhD

Professor

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Locations

Children's Wisconsin - Milwaukee
Froedtert Hospital
Pathology - Children's

Specialties

Pathology
Pediatric Pathology

Languages

English

Contact Information

(414) 266-2860

Education

MD - Doctor of Medicine
PhD

Biography

Dr. North is Professor of Pathology at the Medical College of Wisconsin with a secondary appointment in the MCW Institute for Health and Society. Her primary clinical service responsibilities are in the Division of Pediatric Pathology at Children's Wisconsin. She currently serves as Department Chief for the Children's Medical and Dental Staff in Pathology and Laboratory Medicine. She founded and continues as Scientific Director of the Children's Research Institute Histology Core, a state-of-the-art research-supportive facility that has continually offered a wide range of histology services and Pathology expertise to investigators at MCW and its affiliated institutions since 2006. Dr. North's research program and anatomic clinical practice is most focused in the areas of vascular anomalies and global environmental health.

Research Interests

Pathogenic mechanisms in vascular tumors and malformations of infancy and childhood

Pediatric molecular diagnostics

Global laboratory medicine – development of sustainable models for telepathology-supported laboratory testing in challenging environments

Total Cell-Free DNA Predicts Death and Infection Following Pediatric and Adult Heart Transplantation.

(Scott JP, Ragalie WS, Stamm KD, Mahnke DK, Liang HL, Simpson PM, Dasgupta M, Katz R, North PE, Tomita-Mitchell A, Zangwill SD, Kindel SJ, Mitchell ME.) Ann Thorac Surg. 2020 Oct 08 PMID: 33039362 10/12/2020
Core Hippo pathway components act as a brake on Yap and Taz in the development and maintenance of the biliary network.

(Brandt ZJ, Echert AE, Bostrom JR, North PN, Link BA.) Development. 2020 06 22;147(12) PMID: 32439761 PMCID: PMC7328147 SCOPUS ID: 2-s2.0-85087440712 05/23/2020
Donor fraction cell-free DNA and rejection in adult and pediatric heart transplantation.

(Richmond ME, Zangwill SD, Kindel SJ, Deshpande SR, Schroder JN, Bichell DP, Knecht KR, Mahle WT, Wigger MA, Gaglianello NA, Pahl E, Simpson PM, Dasgupta M, North PE, Hidestrand M, Tomita-Mitchell A, Mitchell ME.) J Heart Lung Transplant. 2020 05;39(5):454-463 PMID: 31983667 SCOPUS ID: 2-s2.0-85078178592 01/28/2020
Early changes in cell-free DNA levels in newly transplanted heart transplant patients.

(Zangwill SD, Kindel SJ, Ragalie WS, North PE, Pollow A, Hidestrand M, Tomita-Mitchell A, Stamm KD, Mitchell ME.) Pediatr Transplant. 2020 02;24(1):e13622 PMID: 31825144 PMCID: PMC7065377 SCOPUS ID: 2-s2.0-85076338475 12/12/2019
Lymphatic-type Angiosarcoma With Prominent Lymphocytic Infiltrate.

(Martinez AP, Zapata M, North PE, Folpe AL, Weiss SW.) Am J Surg Pathol. 2020 02;44(2):271-279 PMID: 31688141 SCOPUS ID: 2-s2.0-85074572550 11/07/2019
Cell-free DNA donor fraction analysis in pediatric and adult heart transplant patients by multiplexed allele-specific quantitative PCR: Validation of a rapid and highly sensitive clinical test for stratification of rejection probability.

(North PE, Ziegler E, Mahnke DK, Stamm KD, Thomm A, Daft P, Goetsch M, Liang HL, Baker MA, Vepraskas A, Rosenau C, Dasgupta M, Simpson P, Mitchell ME, Tomita-Mitchell A.) PLoS One. 2020;15(1):e0227385 PMID: 31929557 PMCID: PMC6957190 SCOPUS ID: 2-s2.0-85077765307 01/14/2020
Multifocal congenital hemangioma: Expanding the pathogenesis of neonatal hemangiomatosis.

(Blumenthal S, Stefanko N, Cossio ML, Coulombe J, McCuaig C, Dubois J, North P, Drolet B.) Pediatr Dermatol. 2019 Sep;36(5):720-722 PMID: 31231857 SCOPUS ID: 2-s2.0-85068095023 06/25/2019
Somatic Mutations of lats2 Cause Peripheral Nerve Sheath Tumors in Zebrafish.

(Brandt ZJ, North PN, Link BA.) Cells. 2019 08 25;8(9) PMID: 31450674 PMCID: PMC6770745 SCOPUS ID: 2-s2.0-85084889096 08/28/2019
Age at Exposure to Radiation Determines Severity of Renal and Cardiac Disease in Rats.

(Lenarczyk M, Kronenberg A, Mäder M, North PE, Komorowski R, Cheng Q, Little MP, Chiang IH, LaTessa C, Jardine J, Baker JE.) Radiat Res. 2019 07;192(1):63-74 PMID: 31095446 SCOPUS ID: 2-s2.0-85068362644 05/17/2019
RASA1-dependent cellular export of collagen IV controls blood and lymphatic vascular development.

(Chen D, Teng JM, North PE, Lapinski PE, King PD.) J Clin Invest. 2019 06 11;129(9):3545-3561 PMID: 31185000 PMCID: PMC6715364 SCOPUS ID: 2-s2.0-85067800404 06/12/2019
Discovery of common chemical exposures across three continents using silicone wristbands.

(Dixon HM, Armstrong G, Barton M, Bergmann AJ, Bondy M, Halbleib ML, Hamilton W, Haynes E, Herbstman J, Hoffman P, Jepson P, Kile ML, Kincl L, Laurienti PJ, North P, Paulik LB, Petrosino J, Points GL 3rd, Poutasse CM, Rohlman D, Scott RP, Smith B, Tidwell LG, Walker C, Waters KM, Anderson KA.) R Soc Open Sci. 2019 Feb;6(2):181836 PMID: 30891293 PMCID: PMC6408398 03/21/2019
Propranolol exhibits activity against hemangiomas independent of beta blockade.

(Sasaki M, North PE, Elsey J, Bubley J, Rao S, Jung Y, Wu S, Zou MH, Pollack BP, Kumar J, Singh H, Arbiser JL.) NPJ Precis Oncol. 2019;3:27 PMID: 31701018 PMCID: PMC6825155 11/09/2019