
Qizhen Shi, MD, PhD
Professor, Pediatric Hematology/Oncology; Senior Investigator, Versiti Blood Research Institute; Secondary Faculty in Cell Biology, Neurobiology, and Anatomy
Locations
- BRI 2013
Contact Information
Research Areas of Interest
- Blood Platelets
- Bone Marrow Transplantation
- Factor VIII
- Genetic Therapy
- Hematopoietic Stem Cell Transplantation
- Hemophilia A
- Hemophilia B
- Hemostasis
- Immune Tolerance
- Lentivirus
- Transduction, Genetic
- Transgenes
Research Experience
- Blood Platelets
- Disease Models, Animal
- Endothelial Cells
- Factor VIII
- Genetic Therapy
- Hematopoietic Stem Cell Transplantation
- Hemophilia A
- Hemophilia A and hemophilia B, platelet-specific gene therapy, immune responses in gene therapy, FVIII immune responses.
- Hemophilia B
- Hemostasis
- Immune Tolerance
- Immunization
Publications
-
The T follicular helper/T follicular helper regulatory pathway in FVIII immune responses in mice.
(Jing W, Schroeder JA, Kumar S, Chen J, Cai Y, Malec LM, Dent AL, Cui W, Shi Q.) Blood. 2025 Jun 10 PMID: 40493881 SCOPUS ID: 2-s2.0-105009644239 06/10/2025
-
(Shi Q, Mattson JG, Morateck PA, Christopherson PA, Schroeder JA, Fahs SA, Rapten J, Schulte ML, Weiler H, Zhu J, Haberichter SL, Flood VH, Montgomery RR.) Haematologica. 2025 May 22 PMID: 40400463 05/22/2025
-
(Kaminski TW, Zhang H, Katoch O, Shi Q, Kato GJ, Sundd P, Pradhan-Sundd T.) Blood Vessel Thromb Hemost. 2025 May;2(2) PMID: 40487985 PMCID: PMC12143466 06/09/2025
-
Platelet-Targeted Gene Therapy for Hemophilia A with Inhibitor History.
(Eapen M, Malec LM, Armant MA, Johnson BD, Shi Q, Xu H, Du LM, Jerkins JH, Duffy LJ, Bushman FD, Lee C, Petrichenko A, Hematti P, Brazauskas R, Jobe SM, Hari PN, Wilcox DA.) N Engl J Med. 2025 Jan 23;392(4):412-414 PMID: 39842018 PMCID: PMC11756741 SCOPUS ID: 2-s2.0-85216608254 01/22/2025
-
(Luo L, An X, Wang Y, Zheng Q, Lin K, Shi Q, Chen Y.) Int Immunopharmacol. 2024 Dec 25;143(Pt 2):113472 PMID: 39471695 PMCID: PMC12117665 SCOPUS ID: 2-s2.0-85207599955 10/30/2024
-
(Chen Z, Zheng Q, Wang Y, An X, Yirga SK, Lin D, Shi Q, Huang M, Chen Y.) Thromb Res. 2024 Dec;244:109196 PMID: 39454362 SCOPUS ID: 2-s2.0-85207009382 10/26/2024
-
(Chen Y, Li J, Schroeder JA, Jing W, Shi Q.) J Thromb Haemost. 2024 Nov;22(11):3035-3047 PMID: 39127324 PMCID: PMC11513242 SCOPUS ID: 2-s2.0-85202518466 08/11/2024
-
(Zheng Q, Lin K, Zhang N, Shi Q, Wu Y, Chen Y.) Int Immunopharmacol. 2024 Sep 30;139:112735 PMID: 39067397 07/28/2024
-
(Strilchuk AW, Hur WS, Batty P, Sang Y, Abrahams SR, Yong ASM, Leung J, Silva LM, Schroeder JA, Nesbitt K, de Laat B, Moutsopoulos NM, Bugge TH, Shi Q, Cullis PR, Merricks EP, Wolberg AS, Flick MJ, Lillicrap D, Nichols TC, Kastrup CJ.) Sci Transl Med. 2024 Feb 21;16(735):eadh0027 PMID: 38381848 PMCID: PMC11293256 SCOPUS ID: 2-s2.0-85185823776 02/21/2024
-
Hematopoietic Stem Cell-Based Platelet-Targeted Gene Therapy for Hemophilia
(Shi Q.) Comprehensive Hematology and Stem Cell Research Volume 1 5. 1 January 2024;5:V5-418 SCOPUS ID: 2-s2.0-85215610065 01/01/2024
-
PACSIN2 regulates platelet integrin β1 hemostatic function.
(Biswas R, Boyd EK, Eaton N, Steenackers A, Schulte ML, Reusswig F, Yu H, Drew C, Kahr WHA, Shi Q, Plomann M, Hoffmeister KM, Falet H.) J Thromb Haemost. 2023 Dec;21(12):3619-3632 PMID: 37678551 PMCID: PMC10841284 SCOPUS ID: 2-s2.0-85172148046 09/08/2023
-
Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression.
(Li J, Karakas D, Xue F, Chen Y, Zhu G, Yucel YH, MacParland SA, Zhang H, Semple JW, Freedman J, Shi Q, Ni H.) Research (Wash D C). 2023;6:0236 PMID: 37808178 PMCID: PMC10551749 10/09/2023