Sara Sabbagh, DO
Associate Professor
Contact Information
Education
Residency, Pediatrics, University of South Florida
Fellowship, Pediatric Rheumatology, Children's National Medical Center and NIH/NIAMS
BS, Molecular Biology and Anthropology, University of Wisconsin-Madison
Biography
Dr. Sara Sabbagh is an associate professor of pediatrics in the division of rheumatology at the Medical College of Wisconsin and Children's Wisconsin. She is a physician-scientist specializing in juvenile dermatomyositis (JDM) and other idiopathic inflammatory myopathies affecting children.
Dr. Sabbagh's research focuses on understanding the mechanisms of vasculopathy – blood vessel dysfunction – in juvenile dermatomyositis. Her long-term goal is to translate these discoveries into novel targeted therapies that improve outcomes for children with this rare autoimmune disease. Her work investigates how immune cells, particularly macrophages and regulatory T cells, interact with blood vessel cells to drive inflammation and tissue damage in JDM.
As a clinician, Dr. Sabbagh brings extensive expertise in caring for children with inflammatory myopathies. She completed her pediatric rheumatology fellowship at Children's National Medical Center and National Institutes of Health (NIH/NIAMS). Following fellowship, she received specialized clinical training in myositis assessments under internationally recognized experts in myositis at the NIH.
Dr. Sabbagh is deeply committed to collaborative research and improving care for children with JDM. She is a member of the Cure JM Clinical Care Network (view the full list of members on their website) and serves as Vice Chair of the International Myositis Assessment and Clinical Studies (IMACS) Meeting Committee, where she helps determine international research priorities and disseminate new developments in myositis research to physicians, researchers, and patient representatives from more than 25 countries. She is also a founding member of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Translational Medicine for Juvenile Myositis working group, which employs collaborative cutting edge bioinformatic and translational science approaches to understand how we can develop precision medicine for myositis patient care and treatment.
Dr. Sabbagh earned her Doctor of Osteopathic Medicine degree from Touro University Nevada and holds dual bachelor's degrees in Molecular Biology and Anthropology from the University of Wisconsin-Madison. She is board certified in Pediatrics and Pediatric Rheumatology and maintains an active clinical practice while pursuing her research mission to improve outcomes for children with inflammatory muscle diseases.
Clinical Expertise
- Juvenile dermatomyositis and inflammatory myopathies
- Pediatric systemic lupus erythematosus
- Juvenile idiopathic arthritis
- Pediatric vasculitis
- Complex pediatric rheumatic diseases
Selected Leadership & Service
- Vice Chair, IMACS Meeting Committee (2025-present)
- Clinical Director, Cure JM Clinical Care Network at Children's Wisconsin (2021-present)
- Founding Member, CARRA Translational Medicine for Juvenile Myositis Working Group
- Principal Investigator, CARRA Registry at MCW
Honors and Awards
Top Provider in Patient Experience, Children's Wisconsin (2023)
APS SPR Journeys & Frontiers in Pediatric Research Cohort (2023)
American Academy of Pediatrics Earl J. Brewer Research Award (2018)
Cure JM Foundation Research Fellowship Award (2018)
Research Interests
- Mechanisms of vasculopathy in juvenile dermatomyositis
- Macrophage and regulatory T cell dysfunction in inflammatory myopathies
- Notch signaling pathway in muscle inflammation and vascular repair
- Autoantibody characterization and clinical associations
- Translational approaches to novel targeted therapies for JDM
Publications
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(Austenfeld EM, Sabbagh SE, Liegl M, Yan K, Do V, Fuller J, Rouster-Stevens K, Rider LG, Schiffenbauer A.) Rheumatology (Oxford). 2026 Jan 08;65(1) PMID: 40996336 SCOPUS ID: 2-s2.0-105029384780 09/25/2025
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(Neely J, Sabbagh SE, Dvergsten J, Madubata C, Berthier CC, Zheng Z, Goudsmit C, Matossian S, Ferris SP, Fragiadakis GK, Sirota M, Kahlenberg JM, Kim H, Turnier JL, CARRA Registry Investigators and CARRA Translational Medicine for Juvenile Myositis Working Group.) Ann Rheum Dis. 2025 Nov;84(11):1836-1851 PMID: 40915939 PMCID: PMC12925510 SCOPUS ID: 2-s2.0-105015351461 09/08/2025
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Updates in juvenile dermatomyositis: pathogenesis and therapy.
(Coss SL, Sabbagh SE, Kim H.) Curr Opin Rheumatol. 2025 Nov 01;37(6):445-456 PMID: 40693918 SCOPUS ID: 2-s2.0-105011663978 07/23/2025
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(Chen KL, Chiu YE, Vleugels RA, Co DO, Kim H, Sabbagh SE, Arkin LM.) J Invest Dermatol. 2025 Jun;145(6):1294-1304 PMID: 39530954 SCOPUS ID: 2-s2.0-85208676459 11/13/2024
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(Tarvin SE, Sherman MA, Kim H, Balmuri N, Brown AG, Chow A, Gewanter HL, de Guzman MM, Huber AM, Kim S, Klein-Gitelman MS, Perron MM, Robinson AB, Sabbagh SE, Savani S, Shenoi S, Spitznagle J, Stingl C, Syverson G, Tory H, Spencer C, Childhood Arthritis and Rheumatology Research Alliance Juvenile Dermatomyositis Workgroup.) Arthritis Care Res (Hoboken). 2024 Nov;76(11):1532-1539 PMID: 38937134 SCOPUS ID: 2-s2.0-85201290324 06/28/2024
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(Venerito V, Fornaro M, Sabbagh S, Ghosh S, Chinoy H, Gupta L, MyoLLM Investigators.) Rheumatology (Oxford). 2024 Oct 01;63(10):e292-e293 PMID: 38648744 SCOPUS ID: 2-s2.0-85205524825 04/23/2024
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(Sabbagh SE, Haribhai D, Gershan JA, Verbsky J, Nocton J, Yassai M, Naumova EN, Hammelev E, Dasgupta M, Yan K, Gorski J, Williams CB.) Front Immunol. 2024;15:1446946 PMID: 38962010 PMCID: PMC11220386 SCOPUS ID: 2-s2.0-85197728513 07/04/2024
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(Sabbagh SE, Haribhai D, Gershan JA, Verbsky J, Nocton J, Yassai M, Naumova EN, Hammelev E, Dasgupta M, Yan K, Gorski J, Williams CB.) Front Immunol. 2024;15:1306490 PMID: 38873594 PMCID: PMC11169902 SCOPUS ID: 2-s2.0-85195642328 06/14/2024
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(Sabbagh SE, Verbsky JW.) Nelson Textbook of Pediatrics Volume 1 2. 1 January 2024:1530-1535.e1 SCOPUS ID: 2-s2.0-85206224972 01/01/2024
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(Karasawa R, Yudoh K, Sato T, Tanaka M, Sabbagh SE, Flegel WA, Mammen AL, Jarvis JN, Rider LG, Childhood Myositis Heterogeneity Study Group.) Rheumatology (Oxford). 2023 Nov 02;62(11):3757-3762 PMID: 37144941 PMCID: PMC10629777 SCOPUS ID: 2-s2.0-85176496767 05/05/2023
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(Sherman MA, Graf R, Sabbagh SE, Galindo-Feria AS, Pinal-Fernandez I, Pak K, Kishi T, Flegel WA, Targoff IN, Miller FW, Lundberg IE, Rider LG, Mammen AL, Childhood Myositis Heterogeneity Collaborative Study Group.) Rheumatology (Oxford). 2023 Feb 23;62(SI2):SI226-SI234 PMID: 35961028 PMCID: PMC9949705 SCOPUS ID: 2-s2.0-85160024916 08/13/2022
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(Karasawa R, Yudoh K, Sato T, Tanaka M, Tamaki M, Sabbagh SE, O'Hanlon TP, Noroozi-Farhadi P, Targoff IN, Flegel WA, Mammen AL, Miller FW, Hicar MD, Rider LG, Jarvis JN.) Rheumatology (Oxford). 2022 Jul 06;61(7):2969-2977 PMID: 34791087 PMCID: PMC9258543 SCOPUS ID: 2-s2.0-85134360741 11/19/2021