Gaurav Kumar, PhD
Postdoctoral Researcher
Locations
- HRC H4630
Contact Information
Education
2021, PhD in Biochemistry, Faculty of Interdisciplinary & Applied Sciences, University of Delhi, South Campus, New Delhi, India.
2010, MSc Biochemistry, H.N.B. Garhwal University, Dolphin (PG) Institute of Biomedical and Natural Sciences, Uttarakhand, India
2010, MSc Biochemistry, H.N.B. Garhwal University, Dolphin (PG) Institute of Biomedical and Natural Sciences, Uttarakhand, India
Biography
I am currently dealing with the identification of novel interacting protein partners in RhoBTB1-Cullin 3 pathway. Using proteomic approaches, I plan to validate them for their potential role in hypertension, pre-eclampsia, and associated cardiovascular impairments.
In parallel, my research explores the transcriptomic functions of RbFox2, a well-characterized RNA-binding protein involved in the regulation of alternative splicing, using various in vitro and in vivo models of hypertension. I am particularly interested in identifying the specific splice variants regulated by RbFox2 in different models of hypertension, as these splicing events may have significant implications for vascular tone, remodeling, and endothelial function in hypertensive states. Together, these studies aim to bridge gaps in our understanding of the molecular underpinnings of hypertension and open new avenues for therapeutic intervention by targeting the protein-protein and RNA-level interactions mediated by RhoBTB1, RbFox2, and Cullins.
View publications
In parallel, my research explores the transcriptomic functions of RbFox2, a well-characterized RNA-binding protein involved in the regulation of alternative splicing, using various in vitro and in vivo models of hypertension. I am particularly interested in identifying the specific splice variants regulated by RbFox2 in different models of hypertension, as these splicing events may have significant implications for vascular tone, remodeling, and endothelial function in hypertensive states. Together, these studies aim to bridge gaps in our understanding of the molecular underpinnings of hypertension and open new avenues for therapeutic intervention by targeting the protein-protein and RNA-level interactions mediated by RhoBTB1, RbFox2, and Cullins.
View publications
Honors and Awards
2025 Professional Development Award – 2023 awarded by Medical College of Wisconsin, USA to attend Hypertension Meeting 2023 conducted by American Heart Association.
2023 Professional Development Award – 2023 awarded by Medical College of Wisconsin, USA to attend Hypertension Meeting 2023 conducted by American Heart Association
2021 Professional Development Award – 2021 awarded by Medical College of Wisconsin, USA to attend Hypertension Meeting 2021 conducted by American Heart Association.
2021 First prize at TRIVIA Quiz Competition organized by Postdoctoral Advisory Committee at Postdoc Appreciation Week-2021 held at Medical College of Wisconsin.
2020 Indian Council of Medical Research (ICMR) travel support to attend American Society for Biochemistry and Molecular Biology (ASBMB) Experimental Biology Annual Meeting -2020. (Not availed due to cancelation of event amid Covid-19)
2020 Suresh C Tyagi oration / Young Scientist Award at The International Conference of Cardiovascular Sciences-2020 (ICCS-2020) at Delhi Pharmaceutical Science and Research University (DPSRU), New Delhi.
2019 Best poster award at International conference on Proteomics for System Integrated Bio-Omics, One Health and Food Safety, Organized by Proteomics Society, India at ICAR-National Dairy Research Institute, Karnal.
2023 Professional Development Award – 2023 awarded by Medical College of Wisconsin, USA to attend Hypertension Meeting 2023 conducted by American Heart Association
2021 Professional Development Award – 2021 awarded by Medical College of Wisconsin, USA to attend Hypertension Meeting 2021 conducted by American Heart Association.
2021 First prize at TRIVIA Quiz Competition organized by Postdoctoral Advisory Committee at Postdoc Appreciation Week-2021 held at Medical College of Wisconsin.
2020 Indian Council of Medical Research (ICMR) travel support to attend American Society for Biochemistry and Molecular Biology (ASBMB) Experimental Biology Annual Meeting -2020. (Not availed due to cancelation of event amid Covid-19)
2020 Suresh C Tyagi oration / Young Scientist Award at The International Conference of Cardiovascular Sciences-2020 (ICCS-2020) at Delhi Pharmaceutical Science and Research University (DPSRU), New Delhi.
2019 Best poster award at International conference on Proteomics for System Integrated Bio-Omics, One Health and Food Safety, Organized by Proteomics Society, India at ICAR-National Dairy Research Institute, Karnal.