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Radiology
Radiology
Alexander Cohen, PhD

Alexander Cohen, PhD

Assistant Professor; Section of Imaging Research, Division of Imaging Sciences

Locations

  • Medical College of Wisconsin

Contact Information

Education

PhD, Medical College of Wisconsin, Milwaukee, WI, 2018
BS, University of Wisconsin - Madison, Madison, WI 2014

Research Interests

The primary goal of my research is to develop quantitative neuroimaging biomarkers that improve our understanding of cerebrovascular health, cognitive aging, and neurodegenerative disease. My work integrates advanced MRI techniques, including arterial spin labeling, cerebrovascular reactivity imaging, diffusion MRI, and functional MRI, to characterize alterations in cerebral perfusion, vascular reserve, and neurovascular function across the aging spectrum, with a particular emphasis on mild cognitive impairment and Alzheimer's disease. Through close collaborations with clinicians and neuroscientists, the goal is to identify imaging markers that can enhance early disease detection, improve patient stratification, and provide insight into factors that predict cognitive resilience or decline.

My current research involves the development of analytical methods that identify complex interactions among multimodal neuroimaging signals. Recent projects have examined coupling between spontaneous fluctuations in cerebral blood flow and functional MRI activity using information-theoretic approaches, including mutual information, to quantify nonlinear aspects of neurovascular synchronization. I am also interested in machine learning techniques that identify distributed patterns of cerebrovascular dysfunction associated with aging and neurodegeneration.

Publications

Publications of Alexander Cohen PhD from the Faculty Collaboration Database

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