Aoy Tomita-Mitchell, PhD

Publications

• Elevated nuclear and mitochondrial cell-free deoxyribonucleic acid measurements are associated with death after infant cardiac surgery.

  (Scott JP, Tanem JM, Tomita-Mitchell A, Hoffman GM, Niebler RA, Liang HL, Simpson PM, Stamm KD, North PE, Mitchell ME.) J Thorac Cardiovasc Surg. 2022 Aug;164(2):367-375 PMID: 35144816 SCOPUS ID: 2-s2.0-85120861361 02/12/2022

• Relationship between donor fraction cell-free DNA and clinical rejection in heart transplantation.

  (Deshpande SR, Zangwill SD, Kindel SJ, Schroder JN, Bichell DP, Wigger MA, Richmond ME, Knecht KR, Pahl E, Gaglianello NA, Mahle WT, Stamm KD, Simpson PM, Dasgupta M, Zhang L, North PE, Tomita-Mitchell A, Mitchell ME.) Pediatr Transplant. 2022 Jun;26(4):e14264 PMID: 35258162 SCOPUS ID: 2-s2.0-85125904987 03/09/2022

• A Systematic Review of Ebstein's Anomaly with Left Ventricular Noncompaction.

  (Thareja SK, Frommelt MA, Lincoln J, Lough JW, Mitchell ME, Tomita-Mitchell A.) J Cardiovasc Dev Dis. 2022 Apr 13;9(4) PMID: 35448091 PMCID: PMC9031964 SCOPUS ID: 2-s2.0-85129039352 04/22/2022

• Increase in nuclear cell-free DNA is associated with major adverse events in adult and pediatric heart transplant recipients.

  (Zangwill SD, Deshpande SR, Simpson PM, Liang HL, Zhang L, Dasgupta M, Richmond ME, Kindel SJ, Bichell DP, Mahle WT, Wigger MA, Schroder JN, Knecht KR, Pahl E, Gaglianello NA, North PE, Tomita-Mitchell A, Mitchell ME.) Clin Transplant. 2022 Jan;36(1):e14509 PMID: 34649304 SCOPUS ID: 2-s2.0-85120575732 10/15/2021

• Total Cell-Free DNA Predicts Death and Infection Following Pediatric and Adult Heart Transplantation.

  (Scott JP, Ragalie WS, Stamm KD, Mahnke DK, Liang HL, Simpson PM, Dasgupta M, Katz R, North PE, Tomita-Mitchell A, Zangwill SD, Kindel SJ, Mitchell ME.) Ann Thorac Surg. 2021 Oct;112(4):1282-1289 PMID: 33039362 SCOPUS ID: 2-s2.0-85103701202 10/12/2020

• Correction: Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease.

  (Audain E, Wilsdon A, Breckpot J, Izarzugaza JMG, Fitzgerald TW, Kahlert AK, Sifrim A, Wünnemann F, Perez-Riverol Y, Abdul-Khaliq H, Bak M, Bassett AS, Benson DW, Berger F, Daehnert I, Devriendt K, Dittrich S, Daubeney PE, Garg V, Hackmann K, Hoff K, Hofmann P, Dombrowsky G, Pickardt T, Bauer U, Keavney BD, Klaassen S, Kramer HH, Marshall CR, Milewicz DM, Lemaire S, Coselli JS, Mitchell ME, Tomita-Mitchell A, Prakash SK, Stamm K, Stewart AFR, Silversides CK, Siebert R, Stiller B, Rosenfeld JA, Vater I, Postma AV, Caliebe A, Brook JD, Andelfinger G, Hurles ME, Thienpont B, Larsen LA, Hitz MP.) PLoS Genet. 2021 Sep;17(9):e1009809 PMID: 34547032 PMCID: PMC8454942 SCOPUS ID: 2-s2.0-85116272362 09/22/2021

• Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease.

  (Audain E, Wilsdon A, Breckpot J, Izarzugaza JMG, Fitzgerald TW, Kahlert AK, Sifrim A, Wünnemann F, Perez-Riverol Y, Abdul-Khaliq H, Bak M, Bassett AS, Benson DW, Berger F, Daehnert I, Devriendt K, Dittrich S, Daubeney PE, Garg V, Hackmann K, Hoff K, Hofmann P, Dombrowsky G, Pickardt T, Bauer U, Keavney BD, Klaassen S, Kramer HH, Marshall CR, Milewicz DM, Lemaire S, Coselli JS, Mitchell ME, Tomita-Mitchell A, Prakash SK, Stamm K, Stewart AFR, Silversides CK, Siebert R, Stiller B, Rosenfeld JA, Vater I, Postma AV, Caliebe A, Brook JD, Andelfinger G, Hurles ME, Thienpont B, Larsen LA, Hitz MP.) PLoS Genet. 2021 Jul;17(7):e1009679 PMID: 34324492 PMCID: PMC8354477 SCOPUS ID: 2-s2.0-85111770757 07/30/2021

• Estimate of the contemporary live-birth prevalence of recurrent 22q11.2 deletions: a cross-sectional analysis from population-based newborn screening.

  (Blagojevic C, Heung T, Theriault M, Tomita-Mitchell A, Chakraborty P, Kernohan K, Bulman DE, Bassett AS.) CMAJ Open. 2021;9(3):E802-E809 PMID: 34404688 PMCID: PMC8373039 SCOPUS ID: 2-s2.0-85114430327 08/19/2021

• Donor fraction cell-free DNA and rejection in adult and pediatric heart transplantation.

  (Richmond ME, Zangwill SD, Kindel SJ, Deshpande SR, Schroder JN, Bichell DP, Knecht KR, Mahle WT, Wigger MA, Gaglianello NA, Pahl E, Simpson PM, Dasgupta M, North PE, Hidestrand M, Tomita-Mitchell A, Mitchell ME.) J Heart Lung Transplant. 2020 May;39(5):454-463 PMID: 31983667 SCOPUS ID: 2-s2.0-85078178592 01/28/2020

• Novel KLHL26 variant associated with a familial case of Ebstein's anomaly and left ventricular noncompaction.

  (Samudrala SSK, North LM, Stamm KD, Earing MG, Frommelt MA, Willes R, Tripathi S, Dsouza NR, Zimmermann MT, Mahnke DK, Liang HL, Lund M, Lin CW, Geddes GC, Mitchell ME, Tomita-Mitchell A.) Mol Genet Genomic Med. 2020 Apr;8(4):e1152 PMID: 31985165 PMCID: PMC7196453 SCOPUS ID: 2-s2.0-85078673520 01/28/2020

• Use of Metformin in Pulmonary Vein Stenosis after TAPVR Repair.

  (Kirkpatrick EC, Mitchell ME, Thilly WG, Cava J, Tomita-Mitchell A, Gostjeva EV.) Glob Pediatr Health. 2020;7:2333794X20958924 PMID: 33029553 PMCID: PMC7522838 10/09/2020

• Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome.

  (Kim MS, Fleres B, Lovett J, Anfinson M, Samudrala SSK, Kelly LJ, Teigen LE, Cavanaugh M, Marquez M, Geurts AM, Lough JW, Mitchell ME, Fitts RH, Tomita-Mitchell A.) Front Cell Dev Biol. 2020;8:440 PMID: 32656206 PMCID: PMC7324479 07/14/2020