Julian Grosskopf
G3 Student
Faculty Advisor
- Michael Lerch, PhD, Biophysics
Locations
- Medical Scientist Training Program
Contact Information
Education
Research Interests
Structural Biology & Biophysics
Research Experience
Medical College of Wisconsin, 2021-present
Advisor: Michael Lerch, PhD
Project: Exploring the molecular mechanisms of lipid head group interactions with the beta-2 adrenergic receptor
University of Wisconsin – La Crosse 2016-2019
Advisors: Drs. Todd Weaver & Daniel Grilley
Projects: 1) Performing site-directed alterations to the hemolysin A non polar core to probe for critical residues of structural and functional importance concerning red blood cell lysis. 2) Calculating and extrapolating chemical and thermal stability of SS loop mutants within fumarase C as part of a larger project in exploring the SS loop and its importance in catalysis of fumarate to S-malate.
Publications
Stuttgen GM, Grosskopf JD, Berger CR, May JF, Bhattacharyya B, Weaver TM. Closed fumarase C active-site structures reveal SS Loop residue contribution in catalysis. FEBS Lett. 2020 Jan;594(2):337-357. doi: 10.1002/1873-3468.13603. Epub 2019 Sep 23. PMID: 31514245.
General Interests
Archery, computer science, functional fitness, and enjoying the outdoors with friends and family