Research Collaborate Lab Bench

Medical Scientist Training Program

Cristhian Gutierrez Huerta

Cristhian Gutierrez Huerta

M1 Student

Faculty Advisor

  • Andreas Beyer, PhD, Physiology and David Gutterman, MD

Locations

  • Medical Scientist Training Program

Contact Information

Education

BS, Applied Mathematics; Biological Sciences, University of California-Merced, 2018

Research Interests

Immunology, immunometabolism, cardiovascular disease, obesity, diabetes, dietary, mitochondrial dynamics and cellular metabolism

Research Experience

Medical College of Wisconsin, 2021-present
Advisor: Andreas Beyer, PhD, Phsiology and David Gutterman, MD

National Heart, Lung, and Blood Institute, 2018- 2020
Advisor: Tiffany M. Powell-Wiley, MD, MPH
Projects: Understanding the biological mechanisms of neighborhood environment and chronic stress induced health disparities, investigating the effects of LDL cholesterol on monocyte subset differentiation and chemokine expression profile, and elucidating the mechanism of obesity-induced NK cell dysfunction

University of Alabama at Birmingham School of Medicine, Summer 2017
Advisor: Joshua S. Speed, PhD
Project: Understanding the effects of high-salt diet on ETa and ETb receptor expression in visceral and subcutaneous adipose tissue

University of California, Merced, 2015- 2016
Advisor: David Ardell, PhD
Project: Utilizing tRNA sequences to phylogenetically classify genome and metagenome datasets

U.S. Department of Energy - Joint Genome Institute, Summer 2015
Advisor: Zhong Wang, PhD
Project: Using consensus-based, supervised machine learning methods on previously unclassified genomes as a predictor of novel bacterial phyla

Publications

Farmer N, Gutierrez-Huerta CA, Turner BS, et al. Neighborhood Environment Associates with Trimethylamine-N-Oxide (TMAO) as a Cardiovascular Risk Marker. Int J Environ Res Public Health. 2021 Apr 18;18(8):4296. doi: 10.3390/ijerph18084296. PMID: 33919545; PMCID: PMC8072883.

Powell-Wiley TM, Dey AK, Rivers JP, Chaturvedi A, Andrews MR, Ceasar JN, Claudel SE, Mitchell VM, Ayers C, Tamura K, Gutierrez-Huerta CA, et al. Chronic Stress-Related Neural Activity Associates With Subclinical Cardiovascular Disease in a Community-Based Cohort: Data From the Washington, D.C. Cardiovascular Health and Needs Assessment. Front Cardiovasc Med. 2021 Mar 10;8:599341. doi: 10.3389/fcvm.2021.599341. PMID: 33778019; PMCID: PMC7988194.

Schwartz DM, Kitakule MM, Dizon BL, Gutierrez-Huerta C, et al. Systematic evaluation of nine monogenic autoinflammatory diseases reveals common and disease-specific correlations with allergy-associated features. Ann Rheum Dis. 2021 Feb 22:annrheumdis-2020-219137. doi: 10.1136/annrheumdis-2020-219137. Epub ahead of print. PMID: 33619160.

Tamura K, Vijayakumar NP, Troendle JF, Curlin K, Neally SJ, Mitchell VM, Collins BS, Baumer Y, Gutierrez-Huerta CA, et al. Multilevel mobile health approach to improve cardiovascular health in resource-limited communities with Step It Up: a randomised controlled trial protocol targeting physical activity. BMJ Open. 2020 Dec 21;10(12):e040702. doi: 10.1136/bmjopen-2020-040702. PMID: 33371027; PMCID: PMC7754642.

Baumer Y, Weatherby TM, Mitchell BI, SahBandar IN, Premeaux TA, Michelle L D, Gutierrez-Huerta CA, et al. Hiding in plain sight - platelets, the silent carriers of HIV-1. Platelets. 2020 Nov 23:1-5. doi: 10.1080/09537104.2020.1849606. Epub ahead of print. PMID: 33222575; PMCID: PMC8141065.

Andrews MR, Ceasar J, Tamura K, Langerman SD, Mitchell VM, Collins BS, Baumer Y, Gutierrez Huerta CA, et al. Neighborhood environment perceptions associate with depression levels and cardiovascular risk among middle-aged and older adults: Data from the Washington, DC cardiovascular health and needs assessment [published online ahead of print, 2020 Jul 21]. Aging Ment Health. 2020;1-12. doi:10.1080/13607863.2020.1793898

Baumer Y, Dey AK, Gutierrez-Huerta CA, et al. Hyperlipidaemia and IFNgamma/TNFalpha Synergism are associated with cholesterol crystal formation in Endothelial cells partly through modulation of Lysosomal pH and Cholesterol homeostasis [published online ahead of print, 2020 Jul 6]. EBioMedicine. 2020;102876. doi:10.1016/j.ebiom.2020.102876

Baumer Y, Gutierrez-Huerta CA, Saxena A, et al. Immune cell phenotyping in low blood volumes for assessment of cardiovascular disease risk, development, and progression: a pilot study. J Transl Med. 2020;18(1):29. Published 2020 Jan 17. doi:10.1186/s12967-020-02207-0

Meeting Abstracts

Gutierrez-Huerta CA, Turner B, Mitchell VM, et al. LDL Drives Pro-Inflammatory Monocyte Subset Differentiation and increases chemokine profile expression in African-American women. NIH Virtual Postbac Poster Day. Bethesda, MD. April 2020.

Gutierrez-Huerta CA, Yu Q, Mitchell VM, et al. LDL-induced changes in monocyte populations and CCR2 expression profile as a potential contributor to CVD risk in African Americans. American Heart Association: Scientific Sessions. Philadelphia, PA. November 2019.

Gutierrez-Huerta CA, Dey AK, Mitchell VM, et al. LDL-induced pro-inflammatory monocyte subset differentiation might be a potential drive for increased CVD in African Americans. Gordon Research Conferences: Atherosclerosis. Newry, Maine. June 2019.

Baumer Y, Dey AK, Sekine Y, Sanda GE, Gutierrez-Huerta CA, et al. IFN and TNF synergistically accelerate endothelial cholesterol crystal formation in part by increasing lysosomal pH. Gordon Research Conferences: Atherosclerosis. Newry, ME. June 2019.

Gutierrez-Huerta CA, Baumer Y, Saxena A, et al. A flow cytometry approach to characterize hematologic cell populations. National Heart Lung, and Blood Institute Research Festival.

Baumer Y, Gutierrez-Huerta CA, Mitchell VM, et al. Socioeconomic Status Modulates the Relationship between Dopamine and Endothelial Cell Lysosomal Function potentially accelerating Cholesterol Crystal Formation. National Heart Lung, and Blood Institute Research Festival. Bethesda, MD. March 2019.

Gutierrez-Huerta CA, Baumer Y, Power-Wiley TM. Linking social science research methods with traditional wet-lab techniques to address cardiovascular health disparities. National Heart, Lung, and Blood Research Festival. Bethesda, MD. March 2019.

General Interests

Going to breweries, hiking, Netflix, reading books, listening to TED talks, and tennis