
Donovan Drouillard
M2 Student
Faculty Advisor
- Michael Dwinell, PhD, Microbiology & Immunology
Locations
- Medical Scientist Training Program
Contact Information
Education
Research Interests
Cancer immunotherapy, pancreatic cancer, and precision medicine
Research Experience
Medical College of Wisconsin, 2021-present
Advisor: Michael Dwinell, PhD
Project: Studying the role of the mucosal chemokines in pancreatitis and pancreatic ductal adenocarcinoma
University of Michigan-Ann Arbor, 2016 - 2018
Advisor: Marina Pasca di Magliano, PhD
Project 1: Determining the role of Beta-1 integrin signaling in providing resistance to MEK inhibition in pancreatic cancer
Project 2: Elucidating the downstream targets of the Hedgehog signaling pathway in pancreatic cancer
University of Michigan-Ann Arbor, 2018 - 2020
Advisor: Flip Bednar, MD, PhD
Project: Identifying the targets of BMI1 in human pancreatic cancer cell lines
Publications
AbuEid M, McAllister DM, McOlash L, Harwig MC, Cheng G, Drouillard D, et al. Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression. iScience. 2021 May 25;24(6):102653. doi: 10.1016/j.isci.2021.102653. PMID: 34189432; PMCID: PMC8220235.
Steele NG, Biffi G, Kemp SB, Zhang Y, Drouillard D, et al. Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer. Clin Cancer Res. 2021 Jan 25. doi: 10.1158/1078-0432.CCR-20-3715. Epub ahead of print. PMID: 33495315.
Brannon A 3rd, Drouillard D, Steele N, et al. Beta 1 integrin signaling mediates pancreatic ductal adenocarcinoma resistance to MEK inhibition. Sci Rep. 2020;10(1):11133. Published 2020 Jul 7. doi:10.1038/s41598-020-67814-9
General Interests
Volleyball, running, hiking, disc golf, going to concerts, traveling, and a good Netflix binge. My favorite sports teams are the Detroit Lions and Michigan Wolverines.