Melissa Anfinson
G5 Student
Faculty Advisor
- Aoy Mitchell, PhD, Cell Biology, Neurobiology & Anatomy
Locations
- Medical Scientist Training Program
Contact Information
Education
Research Interests
Human genetics and pediatric disorders
Research Experience
Medical College of Wisconsin, 2018-present
Advisor: Aoy Mitchell, PhD
Project: The Role of MYH6 Variants in Development and Progression of Hypoplastic Left Heart Syndrome
Yale University, 2015-2016
Advisor: Dr. Lynne Regan
Project: In vitro examination of heat shock factor 1 activation in EGFR-mutant non-small cell lung cancer following HSP90 inhibition
College of St. Benedict, 2014-2015
Advisor: Dr. Rachel Hutcheson
Project: Investigating uncharacterized radical S-adenosylmethionine enzymes
Publications
Anfinson M, Fitts RH, Lough JW, James JM, Simpson PM, Handler SS, Mitchell ME, Tomita-Mitchell A. Significance of α-Myosin Heavy Chain (MYH6) Variants in Hypoplastic Left Heart Syndrome and Related Cardiovascular Diseases. J Cardiovasc Dev Dis. 2022 May 3;9(5):144. doi: 10.3390/jcdd9050144. PMID: 35621855; PMCID: PMC9147009.
Kim M, Fleres B, Lovett J, Anfinson M, Samudrala S, et al. Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome. Front Cell Dev Biol. 2020;8:440. Published 2020 Jun 23. doi:10.3389/fcell.2020.00440
Meeting Abstracts
M Quintanilla, A Knutson, K Pundsack, E Boysen, B Kor, M Reagan. Use of decongestants may disrupt cell signaling pathways that control Tbx gene expression, leading to Hypoplastic Left Heart Syndrome. Oral and Poster Presentation at Mayo Clinic IMPACT Symposium. Mayo Clinic Center for Regenerative Medicine, Rochester, MN. February 2015.
ML Quintanilla, KL Mathewson, R Jones, KW Olsen. Synthesis of folate-targeted protein-based photodynamic therapy agents. Poster Presentation. Poster Presentation at Midwest Enzyme Chemistry Conference. Loyola University Chicago, Chicago, IL. October 2013.
General Interests
Running, cooking, dogs, crafts, outdoors