Medical Scientist Training Program
Medical Scientist Training Program
Melissa Anfinson

Melissa Anfinson

G5 Student

Faculty Advisor

  • Aoy Mitchell, PhD, Cell Biology, Neurobiology & Anatomy


  • Medical Scientist Training Program

Contact Information


BA, Chemistry - Chemical Biology, College of St. Benedict, 2015

Research Interests

Human genetics and pediatric disorders

Research Experience

Medical College of Wisconsin, 2018-present
Advisor: Aoy Mitchell, PhD
Project: The Role of MYH6 Variants in Development and Progression of Hypoplastic Left Heart Syndrome

Yale University, 2015-2016
Advisor: Dr. Lynne Regan
Project: In vitro examination of heat shock factor 1 activation in EGFR-mutant non-small cell lung cancer following HSP90 inhibition

College of St. Benedict, 2014-2015
Advisor: Dr. Rachel Hutcheson
Project: Investigating uncharacterized radical S-adenosylmethionine enzymes


Anfinson M, Fitts RH, Lough JW, James JM, Simpson PM, Handler SS, Mitchell ME, Tomita-Mitchell A. Significance of α-Myosin Heavy Chain (MYH6) Variants in Hypoplastic Left Heart Syndrome and Related Cardiovascular Diseases. J Cardiovasc Dev Dis. 2022 May 3;9(5):144. doi: 10.3390/jcdd9050144. PMID: 35621855; PMCID: PMC9147009.

Kim M, Fleres B, Lovett J, Anfinson M, Samudrala S, et al. Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome. Front Cell Dev Biol. 2020;8:440. Published 2020 Jun 23. doi:10.3389/fcell.2020.00440

Meeting Abstracts

M Quintanilla, A Knutson, K Pundsack, E Boysen, B Kor, M Reagan. Use of decongestants may disrupt cell signaling pathways that control Tbx gene expression, leading to Hypoplastic Left Heart Syndrome. Oral and Poster Presentation at Mayo Clinic IMPACT Symposium. Mayo Clinic Center for Regenerative Medicine, Rochester, MN. February 2015.

ML Quintanilla, KL Mathewson, R Jones, KW Olsen. Synthesis of folate-targeted protein-based photodynamic therapy agents. Poster Presentation. Poster Presentation at Midwest Enzyme Chemistry Conference. Loyola University Chicago, Chicago, IL. October 2013.

General Interests

Running, cooking, dogs, crafts, outdoors