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MSTP students in the Sahoo lab
Medical Scientist Training Program
Ryan Bonate

Ryan Bonate

G3 Student

Faculty Advisor

  • Eric Paulson, PhD, Biophysics

Locations

  • Medical Scientist Training Program

Contact Information

Education

BS, Biophysics; Mathematics, Loyola University, 2021

Research Interests

My research interests are in imaging science and radiation oncology. My dissertation work focuses on the utilization of quantitative MRI towards biologically adaptive radiation therapy in head and neck cancer.

Research Experience

Medical College of Wisconsin, 2023-Present
Advisors: Eric Paulson, PhD
Project: PARADIGM: Personalized, adaptive radiotherapy applying day-of-treatment imaging guidance from qMRI

Loyola University-Chicago, 2020-2021
Advisor: Thomas Sanger, PhD
Project: Use embryonal gecko tissue to observe and categorize the sexual development of geckos in vivo

Publications

Bonate R, Awan MJ, Himburg HA, Wong S, Shukla M, Tarima S, et al. (2025). Quantitative magnetic resonance imaging responses in head and neck cancer patients treated with magnetic resonance-guided hypofractionated radiation therapy. Phys Imaging Radiat Oncol 2025;33:100693. https://doi.org/10.1016/j.phro.2024.100693.

Bonate R, Kurek G, Hrabak M, Patterson S, Padovan-Neto F, West AR, Steiner H. Phosphodiesterase 10A (PDE10A): Regulator of Dopamine Agonist-Induced Gene Expression in the Striatum. Cells. 2022 Jul 16;11(14):2214. doi: 10.3390/cells11142214. PMID: 35883657; PMCID: PMC9324899.

Egner JM, Nolden KA, Harwig MC, Bonate RP, De Anda J, Tessmer MH, Noey EL, Ihenacho UK, Liu Z, Peterson FC, Wong GCL, Widlansky ME, Hill RB. Structural studies of human fission protein FIS1 reveal a dynamic region important for GTPase DRP1 recruitment and mitochondrial fission. J Biol Chem. 2022 Dec;298(12):102620. doi: 10.1016/j.jbc.2022.102620. Epub 2022 Oct 20. PMID: 36272645; PMCID: PMC9747602.

Meeting Abstracts

Bonate R, Paulson E, Frei A, Shukla M, Tarima S, Wong S, Himburg H., Zenga J, Awan M. (2023). Differential Response in Quantitative MRI Parameters Detected in Head and Neck Cancer Patients Treated with Concurrent Immunotherapy during Hypo-Fractionated MR-gRT. International Journal of Radiation Oncology*Biology*Physics, 117(2), S65.

Bonate R, Awan M, Shukla M, Tarima S, Himburg H, Zenga J, Paulson E. (2024). Patterns of Response in HNSCC Subregions Using Daily Quantitative MRI from MR-Guided Radiation Therapy. International Journal of Radiation Oncology*Biology*Physics, 120(2), S101.

Bonate R, Sullivan R, Crowley H, Bielanski A, Suarez V. Next-generation prenatal testing [Internet]. CELTS; Undergraduate Research and Engagement Symposium: Loyola University, Chicago 2021.

Bonate RP, Laps ED. Genital development in an all-female lizard species, Lepidodactylus lugubris [Internet]. CELTS; Undergraduate Research and Engagement Symposium: Loyola University, Chicago 2021.

General Interests

Translational research, especially clinical trial work, is of special interest to me. Biostatistics has also found a spot near and dear to me as of late and I am pursuing a Master's in Biostatistics in addition to my PhD work. Outside of work, my hobbies include cooking, gardening, weightlifting, and cycling.

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