
Dominic B. Fee, MD
Vice Chair, Professor
Location
- Froedtert Hospital
- 900 N. 92nd St.
- Milwaukee, WI 53226
Specialties
- Neurology
- Neuromuscular Medicine
Neuroscience Center - Froedtert Hospital Specialty Clinics
Overview
Diseases and Conditions
- ALS
- Carpal Tunnel Syndrome
- Mitochondrial Disorders
- Muscle Diseases
- Myasthenia Gravis
- Dermatomyositis
- Stiff Person Syndrome (SPS)
- Neuropathy
- Polyneuropathy
- Myopathy
- Muscular Dystrophy
- Brachial Plexopathy
- Autonomic Ganglionopathy
- Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
- Charcot-Marie-Tooth Disease (CMT)
- Friedreich's Ataxia (FA)
- Guillain-Barre
- Lambert-Eaton Myasthenic Syndrome (LEMS)
- Fasciculations
Treatments and Services
- Electromyography (EMG)
- Nerve Conduction Studies (NCVs)
- Muscle Biopsies
- Virtual Visit
Patients Ages Seen
- Infant
- Child
- Adolescent
- Adult
- Senior
Languages
- English
Hospital Affiliations
- Children's Wisconsin - Milwaukee – Milwaukee
- Froedtert Hospital – Milwaukee
Board Certifications
- Neurology
- Clinical Neurophysiology
- Electrodiagnostic Medicine
- Neuromuscular Medicine
Clinic Locations
Froedtert Hospital
- 900 N. 92nd St.
- Milwaukee, WI 53226
- (414) 805-3000
- Get Directions

Biography
Education and Training
Doctor of Medicine - University of Iowa College of Medicine - Iowa City, IA (1996)
Internship in Internal Medicine - Northwestern University - Evanston - Evanston, IL (1996-1997)
Residency in Neurology - University of Wisconsin Hospitals and Clinics - Madison, WI (1997-2000)
Fellowship in Neuromuscular Disease/Clinical Neurophysiology - University of Wisconsin Hospitals and Clinics - Madison, WI (2000-2002)
Fellowship in Neurogenetics - Cedars-Sinai Medical Center - Los Angeles, CA (2003-2004)
Publications
-
(Harkey BA, Distefano S, Pagliaro JA, Heyd L, Chase M, Igne C, Yu H, Sherman AV, Dagostino D, Tustison E, Changkuon G, Hall M, Kittle G, Connolly MR, Giacomelli E, Scirocco E, Berry JD, Babu S, Shefner J, Macklin EA, Chibnik LB, De Mattos A, Drake K, Kamp C, McGarry A, Torti M, Small C, Bulat A, Cudkowicz ME, Paganoni S, HEALEY ALS Platform Trial Study Group.) Muscle Nerve. 2025 Aug;72(2):294-305 PMID: 40420561 SCOPUS ID: 2-s2.0-105007077617 05/27/2025
-
(Shefner JM, Cudkowicz ME, Genge A, Hardiman O, Al-Chalabi A, Andrews JA, Chio A, Corcia P, Couratier P, de Carvalho M, Heiman-Patterson T, Henderson RD, Ingre C, Johnston W, Ludolph A, Maragakis NJ, Miller TM, Mora JS, Petri S, Simmons Z, van den Berg LH, Zinman L, Kupfer S, Malik FI, Meng L, Simkins TJ, Wei J, Wolff AA, Rudnicki SA, COURAGE-ALS Study Group.) JAMA Neurol. 2025 May 01;82(5):477-485 PMID: 40126464 PMCID: PMC11933997 SCOPUS ID: 2-s2.0-105002743538 03/24/2025
-
(Writing Committee for the HEALEY ALS Platform Trial, Andrews J, Paganoni S, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Young E, Chase M, Pothier L, Harkey B, Yu H, Sherman A, Shefner J, Hall M, Kittle G, Connolly MR, Berry JD, D'Agostino D, Tustison E, Giacomelli E, Scirocco E, Alameda G, Locatelli E, Ho D, Quick A, Heitzman D, Ajroud-Driss S, Appel SH, Shroff S, Katz J, Felice K, Maragakis NJ, Simmons Z, Goutman SA, Olney N, Miller T, Fernandes JA, Ilieva H, Jawdat O, Weiss MD, Foster L, Vu T, Ladha S, Owegi MA, Newman DS, Arcila-Londono X, Jackson CE, Swenson A, Heiman-Patterson T, Caress J, Fee D, Peltier A, Lewis R, Rosenfeld J, Walk D, Johnson K, Elliott M, Kasarskis EJ, Rutkove S, McIlduff CE, Bedlack R, Elman L, Goyal NA, Rezania K, Twydell P, Benatar M, Glass J, Cohen JA, Jones V, Zilliox L, Wymer JP, Beydoun SR, Shah J, Pattee GL, Martinez-Thompson J, Nayar S, Granit V, Donohue M, Grossman K, Campbell DJ, Qureshi IA, Cudkowicz ME, Babu S.) JAMA Neurol. 2025 Apr;82(4):333-343 PMID: 40067754 PMCID: PMC11833655 SCOPUS ID: 2-s2.0-105003693721 03/12/2025
-
CNM-Au8 in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial.
(Writing Committee for the HEALEY ALS Platform Trial, Berry JD, Maragakis NJ, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Stommel EW, Chase M, Pothier L, Harkey BA, Yu H, Sherman A, Shefner J, Hall M, Kittle G, Babu S, Andrews J, D'Agostino D, Tustison E, Scirocco E, Giacomelli E, Alameda G, Locatelli E, Ho D, Quick A, Ajroud-Driss S, Katz J, Heitzman D, Appel SH, Shroff S, Felice KJ, Simmons Z, Miller T, Olney N, Weiss MD, Goutman SA, Fernandes JA Jr, Jawdat O, Owegi MA, Foster L, Vu T, Ilieva H, Newman DS, Arcila-Londono X, Jackson C, Ladha S, Heiman-Patterson T, Caress J, Swenson A, Peltier A, Lewis R, Fee D, Elliott M, Bedlack R, Kasarskis EJ, Elman L, Rosenfeld J, Walk D, McIlduff CE, Twydell P, Young E, Johnson K, Rezania K, Goyal NA, Cohen JA, Benatar M, Jones V, Glass J, Shah J, Beydoun SR, Wymer JP, Zilliox L, Nayar S, Pattee GL, Martinez-Thompson J, Rynders A, Evan J, Evan J, Hartford A, Sepassi M, Ho KS, Glanzman R, Greenberg B, Hotchkin MT, Paganoni S, Cudkowicz ME, HEALEY ALS Platform Trial Study Group.) JAMA. 2025 Feb 17;333(13):1138-49 PMID: 40067821 PMCID: PMC11833661 SCOPUS ID: 2-s2.0-105003032316 03/12/2025
-
Pridopidine in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial.
(Writing Committee for the HEALEY ALS Platform Trial, Shefner JM, Oskarsson B, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Heiman-Patterson T, Chase M, Pothier L, Harkey BA, Yu H, Sherman AV, Hall M, Kittle G, Berry JD, Babu S, Andrews J, D'Agostino D, Tustison E, Scirocco E, Giacomelli E, Alameda G, Locatelli E, Ho D, Quick A, Ajroud-Driss S, Katz J, Heitzman D, Appel SH, Shroff S, Felice K, Maragakis NJ, Simmons Z, Miller TM, Olney N, Weiss MD, Goutman SA, Fernandes JA, Jawdat O, Owegi MA, Foster LA, Vu T, Ilieva H, Newman DS, Arcila-Londono X, Jackson CE, Ladha S, Caress JB, Swenson A, Peltier A, Lewis RA, Fee D, Elliott M, Bedlack R, Kasarskis EJ, Elman L, Rosenfeld J, Walk D, McIlduff C, Twydell P, Young E, Johnson K, Rezania K, Goyal NA, Cohen JA, Benatar M, Jones V, Shah J, Beydoun SR, Wymer JP, Zilliox L, Nayar S, Pattee GL, Martinez-Thompson J, Leitner ML, Chen K, Goldberg YP, Cohen Y, Geva M, Hayden MR, Paganoni S, Cudkowicz ME, HEALEY ALS Platform Trial Study Group.) JAMA. 2025 Feb 17;333(13):1128-37 PMID: 40067755 PMCID: PMC11833658 SCOPUS ID: 2-s2.0-105003026814 03/12/2025
-
Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.
(Paganoni S, Fournier CN, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Ajroud-Driss S, Chase M, Pothier L, Harkey BA, Yu H, Sherman AV, Shefner JM, Hall M, Kittle G, Berry JD, Babu S, Andrews J, Dagostino D, Tustison E, Giacomelli E, Scirocco E, Alameda G, Locatelli E, Ho D, Quick A, Katz J, Heitzman D, Appel SH, Shroff S, Felice K, Maragakis NJ, Simmons Z, Miller TM, Olney N, Weiss MD, Goutman SA, Fernandes JA, Jawdat O, Owegi MA, Foster LA, Vu T, Ilieva H, Newman DS, Arcila-Londono X, Jackson CE, Ladha S, Heiman-Patterson T, Caress JB, Swenson A, Peltier A, Lewis R, Fee D, Elliott M, Bedlack R, Kasarskis EJ, Elman L, Rosenfeld J, Walk D, McIlduff C, Twydell P, Young E, Johnson K, Rezania K, Goyal NA, Cohen JA, Benatar M, Jones V, Glass J, Shah J, Beydoun SR, Wymer JP, Zilliox L, Nayar S, Pattee GL, Martinez-Thompson J, Harvey B, Patel S, Mahoney P, Duda PW, Cudkowicz ME, HEALEY ALS Platform Trial Study Group.) JAMA Netw Open. 2025 Feb 03;8(2):e2459058 PMID: 39960672 PMCID: PMC11833520 SCOPUS ID: 2-s2.0-85218953640 02/17/2025
-
Design and Statistical Innovations in a Platform Trial for Amyotrophic Lateral Sclerosis.
(Quintana M, Saville BR, Vestrucci M, Detry MA, Chibnik L, Shefner J, Berry JD, Chase M, Andrews J, Sherman AV, Yu H, Drake K, Cudkowicz M, Paganoni S, Macklin EA, HEALEY ALS Platform Trial Study Group.) Ann Neurol. 2023 Sep;94(3):547-560 PMID: 37245090 SCOPUS ID: 2-s2.0-85163197066 05/28/2023
-
Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development
(Paganoni S, Berry JD, Quintana M, Macklin E, Saville BR, Detry MA, Chase M, Sherman AV, Yu H, Drake K, Andrews J, Shefner J, Chibnik LB, Vestrucci M, Cudkowicz ME, Macklin E, Quintana M, Saville BR, Detry MA, Chibnik LB, Bind MA, Chan J, Vestrucci M, Locatelli E, Alameda G, Paganoni S, Cudkowicz ME, McCaffrey A, Berry J, Babu S, Nicholson K, Scalia J, Simmons Z, Grogan J, Su X, Mamarabadi M, Heitzman D, Nasri MA, Katz J, Jenkins L, Felice K, Whitaker C, Ajroud-Driss S, Quick A, Kolb S, Sarah Heintzman NP, Appel SH, Greene E, Thonhoff J, Shroff S, Liao B, Goutman SA, Feldman EL, Miller T, Amber Malcolm NP, Newman DS, Arcila-Londono X, Steijlen K, Owegi MA, Brown RH, Ghasemi M, Fernandes JAM, Piccione E, Thaisetthawatkul P, Weiss MD, Rad N, Ilieva H, Pasinelli P, Judith Guarnieri NP, Ladha S, Jacobsen B, Bowser R, Shefner J, Foster L, Jackson C, Rosenfeld J, Bhuvaneswaran K, Elman L, Quinn C, Julia Yasek NP, Fee D, Heiman-Patterson T, Deboo A, Swenson A, Nance C, Vu T, Suresh N, Farias J, Caress J, Cartwright M, Rezania K, Elliott M, Rutkove S, McIlduff C, Cohen JA, Stommel E, Glass J, Fournier C, Young E, Wymer JP.) Annals of Neurology. 01 February 2022;91(2):165-175 SCOPUS ID: 2-s2.0-85122780992 02/01/2022
-
A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS.
(Shefner JM, Andrews JA, Genge A, Jackson C, Lechtzin N, Miller TM, Cockroft BM, Meng L, Wei J, Wolff AA, Malik FI, Bodkin C, Brooks BR, Caress J, Dionne A, Fee D, Goutman SA, Goyal NA, Hardiman O, Hayat G, Heiman-Patterson T, Heitzman D, Henderson RD, Johnston W, Karam C, Kiernan MC, Kolb SJ, Korngut L, Ladha S, Matte G, Mora JS, Needham M, Oskarsson B, Pattee GL, Pioro EP, Pulley M, Quan D, Rezania K, Schellenberg KL, Schultz D, Shoesmith C, Simmons Z, Statland J, Sultan S, Swenson A, Berg LHVD, Vu T, Vucic S, Weiss M, Whyte-Rayson A, Wymer J, Zinman L, Rudnicki SA.) Amyotroph Lateral Scler Frontotemporal Degener. 2021 May;22(3-4):287-299 PMID: 32969758 PMCID: PMC8117790 SCOPUS ID: 2-s2.0-85091435875 09/25/2020
-
(Cudkowicz M, Genge A, Maragakis N, Petri S, van den Berg L, Aho VV, Sarapohja T, Kuoppamäki M, Garratt C, Al-Chalabi A, Kiernan M, Mathers S, Henderson R, Needham M, Schultz D, Löscher W, Mitrovic N, Rath J, Damme PV, De Bleecker JL, Delstanche S, Johnston W, Zinman L, O'Connell C, Matte G, Dionne A, Korngut L, Turnbull J, Laaksovirta H, Jokela M, Tapiola T, Soriani MH, Couratier P, Camu W, Corcia P, Ludolph A, Großkreutz J, Meyer T, Boentert M, Schrank B, Prudlo J, Untucht R, Hardiman O, Siciliano G, Chio' A, Mazzini L, Inghilleri M, Caponnetto C, Mora G, Mora Pardina JS, Farrero Munoz E, Vázquez Costa JF, Aguera Morales E, Varona L, Andersen P, Ingre C, Johansson R, Radunovic A, Young C, Babu S, Shaibani A, Staff N, Vu T, Rivner M, Scelsa S, Sivakumar K, Waheed W, Heitzman D, Rana S, Pattee G, Ajroud-Driss S, Bayat E, Kasarskis E, Lange DJ, Elliott M, Harris B, Felice K, Pulley MT, Kwan J, Brown M, Ravits J, Burford M, Karam C, Miller T, Andrews J, Levine T, Locatelli E, Wymer J, Bedlack R, Fee D, Goyal N, Oskarsson B, McCluskey L, Caress J, Weiss M, Quick A, Bromberg M, Lacomis D, Goutman S, Rezania K.) Lancet Neurology. October 2021;20(10):821-831 SCOPUS ID: 2-s2.0-85114911882 10/01/2021
-
(Kavanaugh MS, Cho Y, Fee D, Barkhaus PE.) Neurodegener Dis Manag. 2020 Aug;10(4):231-241 PMID: 32749175 SCOPUS ID: 2-s2.0-85095932496 08/05/2020
-
Novel destabilizing Dynactin variant (DCTN1 p.Tyr78His) in patient with Perry syndrome.
(Čierny M, Hooshmand SI, Fee D, Tripathi S, Dsouza NR, La Pean Kirschner A, Zimmermann MT, Brennan R.) Parkinsonism Relat Disord. 2020 Aug;77:110-113 PMID: 32712562 SCOPUS ID: 2-s2.0-85088215494 07/28/2020