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Project Wonder - The art of science at the Medical College of Wisconsin

“Little Heart Warrior”

At just six years old, William—the inspiration behind the operetta “Little Heart Warrior” produced by Jill Anna Ponasik of Milwaukee Opera Theatre—has already lived through more medical challenges than most people face in a lifetime.

Born with a congenital heart defect that causes arrhythmia, William’s earliest days were filled with the sounds of machines and monitors in the neonatal intensive care unit, sounds echoed in the music composed by Autumn Maria Reed.


“In William’s story, there’s a movement from silence and uncertainty to playfulness and calm, It’s about growth, possibility, and the chance to simply live.”

Thanks to expert care informed by advances in precision medicine developed by Drs. Brandon Tefft and Aoy Tomita Mitchell, William can now run, jump, and play like other children his age. For the researchers, William’s health is not only a personal victory, it reflects what cutting-edge science can achieve for children facing complex conditions.
Seeing the impact of their work reflected in this piece provided a vivid reminder of the human side of science and the motivation to keep striving for new discoveries, says Dr. Tomita Mitchell.

“Seeing our research featured in this project was transformative and inspiring,” she says. “It makes you want to keep pushing forward.

The drawings featured in the video, created by William and animated by Dave Kiehl, trace his journey from fragile beginnings to a vibrant present.

Throughout his childhood, William has drawn self-portraits with his heart—an anatomical heart—at the center. His artwork illustrates that his medical condition is not separate from who he is, but an integral part of his identity.

“In William’s story, there’s a movement from silence and uncertainty to playfulness and calm,” says Reed, who mirrored that movement in the score. “It’s about growth, possibility, and the chance to simply live.”

By blending William’s artwork with music and animation, the piece makes visible what data alone cannot.

“When you see William’s artwork and hear his story, it becomes so much more powerful,” says Dr. Tefft. “Statistics don’t resonate the way stories do. Behind every number is a child with creativity, talent, and hope.”

William’s journey stands as a testament to the importance and promise of research. Scientific innovation gave him the opportunity for a healthy childhood. Through art, his story now helps others see both the urgency and the promise of advancing medicine.

Composer: Autumn Maria Reed
Soprano: Michaela Usher
Tenor: Austin Bare
Pianist: Steph Lippert
Inspiration and Drawings: William the Heart Warrior
Animator: Dave Kiehl


Director, Producer, Recording: Alexander Boyes, Medical College of Wisconsin
Producer: Jill Anna Ponasik, Milwaukee Opera Theater
Producer: Wes Tank, TankThink
Written Piece: Meisi Li
Consultation: Drs. Brandon Tefft and Aoy Tomita Mitchell

Project Wonder: The Sounds of Science

We commissioned local musicians to explore and interpret the life-changing science happening at MCW in a creative music video format produced in partnership with Wes Tank of TankThink. Artists were given creative freedom to create music based on the consultation of MCW scientists. The resulting pieces are intended to bring scientific research to life in a deeply human way, highlighting the power of engaging Milwaukee’s diverse community of artists.

Making of "Little Heart Warrior"

  • The beat in the song was made using a 1970’s analog device called the PhonoCardioSimulator. The device was designed to simulate cardiac sounds for training purposes and was set to arrhythmia for this piece.

  • The piano was recorded in Steph Lippert’s home on her heirloom upright. The full tone of the vintage piano is presented, including mechanical noise, to symbolize William’s unique early experiences in the NICU.

Learn More

Congenital heart disease is the leading cause of death related to birth defects and affects 1 out of every 100 live births. Induced pluripotent stem cell technology has allowed for patient-derived cardiomyocytes to be studied in vitro. To help address this, Drs. Brandon Tefft and Aoy Tomita Mitchell developed a protocol to create 3D-bioprinted heart tissue from patients’ own cells, providing a realistic model for studying the disease and testing individualized treatments.

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What if 3D printing technology could help treat heart disease or repair congenital heart defects?
Project Wonder: Cardiovascular Regenerative Engineering
The Medical College of Wisconsin Division of Congenital Heart Surgery is focused on providing the best care to our patients, identifying ways improve outcomes, educating future physicians and researchers, and researching cures for congenital heart disease.
Division of Congenital Heart Surgery