Department of Urology Clinical Research Trials

The Clinical Research Trials Program is dedicated to improving health care in Wisconsin. The Clinical Research Trials Program is composed of a multidisciplinary team committed to exploring promising drugs, new devices, technologies and procedures capable of improving the quality and quantity of life in patients with urologic disease. In addition, the Clinical Research Trials program is the oldest and most experienced center in the State of Wisconsin for conducting studies aimed at preventing urologic disease including prostate cancer. We pledge to meet the needs of our patients and their families through our devotion in providing superior health care. We offer translational research including Phase I, II, III, and IV trials. Our group also works in conjunction with the multidisciplinary cancer center team to evaluate participants for different investigational trials within the Cancer Center. The Clinical Research Trials Program is a core component of the Department of Urology and is critical to our department mission to the pursuit of excellence and leadership in education, research, patient care, and services for the betterment of human health.

For more information, please contact Heather Engelke at (414) 955-0878

Current Trials


Urologic Problem

Primary Investigator


A Phase 4, Double-Blind, Randomized, Placebo-controlled, Multi-Center Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Men with Overactive Bladder (OAB) Symptoms While Taking the Alpha Blocker Tamsulosin Hydrochloride for Lower Urinary Tract Symptoms (LUTS) due to Benign Prostatic Hyperplasia (BPH). #178-MA-1008

Male Overactive Bladder

Michael Guralnick, MD

Open for enrollment

A Phase III, Multicenter, Randomized, Double Blind, Parallel Group, Placebo Controlled Study to Assess the Efficacy and Safety of One or More Intradetrusor Treatments of  600 or 800 Units of Dysport® for the Treatment of Urinary Incontinence in Subjects with Neurogenic Detrusor Overactivity due to Spinal Cord Injury or Multiple Sclerosis

Neurogenic Bladder

Corey O'Connor, MD Open for enrollment

Ex Vivo Thermoacoustic Imaging of Prostate Specimens for Cancer Localization

Prostate Cancer

Sarah Patch, PhD

Open for enrollment

MicroRNA Distribution along Human Nephrons Bank

Renal Cell Cancer

Mingyu Liang, PhD

Open for enrollment

Future studies:

  • Vaccine trial for renal cell cancer
  • Study for metastatic prostate cancer

Past studies:

  • Prostate cancer vaccines
  • Osteoporosis due to hormone therapy for prostate cancer
  • Prostate cancer prevention
  • Benign Prostatic Hyperplasia (BPH), Prostatitis
  • Treatment of hot flashes in Prostate Cancer Patients
  • Erectile Dysfunction
  • Testicular Prosthesis
  • Overactive Bladder/Incontinence
  • InTone Urinary Incontinence Device
  • HIFU (High Intensity Focused Ultrasound) Imaging for Prostate Cancer

Please note that our objective is to provide a current list of available clinical trials. A listing does not guarantee that a trial is open to enrollment, and there may be additional trials available that are not listed. Please contact your urologist or the research data coordinator number provided for complete information.

Other Resources

Information for Patients or Potential Research Participants

MCW Resources

List of websites to assist in your search for Clinical Trials
Information on clinical trials nationwide, including fact sheets and tutorials on how to search for a trial

National Cancer Institute Clinical Trials
Cancer clinical trials as well as brochures and fact sheets for cancer patients

Southwest Oncology Group. A national clinical research group

Center Watch
Clinical Trials listing service

Additional Resources

Food and Drug Administration
The latest information on investigational drugs

Consumer health information from the National Institutes of Health

U.S. Department of Health and Human Services
The federal agency that oversees the Food and Drug Administration