Aoy Tomita-Mitchell, PhD

Publications

• Donor fraction cell-free DNA and rejection in adult and pediatric heart transplantation.

  (Richmond ME, Zangwill SD, Kindel SJ, Deshpande SR, Schroder JN, Bichell DP, Knecht KR, Mahle WT, Wigger MA, Gaglianello NA, Pahl E, Simpson PM, Dasgupta M, North PE, Hidestrand M, Tomita-Mitchell A, Mitchell ME.) J Heart Lung Transplant. 2020 May;39(5):454-463 PMID: 31983667 SCOPUS ID: 2-s2.0-85078178592 01/28/2020

• Novel KLHL26 variant associated with a familial case of Ebstein's anomaly and left ventricular noncompaction.

  (Samudrala SSK, North LM, Stamm KD, Earing MG, Frommelt MA, Willes R, Tripathi S, Dsouza NR, Zimmermann MT, Mahnke DK, Liang HL, Lund M, Lin CW, Geddes GC, Mitchell ME, Tomita-Mitchell A.) Mol Genet Genomic Med. 2020 Apr;8(4):e1152 PMID: 31985165 PMCID: PMC7196453 SCOPUS ID: 2-s2.0-85078673520 01/28/2020

• Early changes in cell-free DNA levels in newly transplanted heart transplant patients.

  (Zangwill SD, Kindel SJ, Ragalie WS, North PE, Pollow A, Hidestrand M, Tomita-Mitchell A, Stamm KD, Mitchell ME.) Pediatr Transplant. 2020 02;24(1):e13622 PMID: 31825144 PMCID: PMC7065377 SCOPUS ID: 2-s2.0-85076338475 12/12/2019

• Cell-free DNA donor fraction analysis in pediatric and adult heart transplant patients by multiplexed allele-specific quantitative PCR: Validation of a rapid and highly sensitive clinical test for stratification of rejection probability.

  (North PE, Ziegler E, Mahnke DK, Stamm KD, Thomm A, Daft P, Goetsch M, Liang HL, Baker MA, Vepraskas A, Rosenau C, Dasgupta M, Simpson P, Mitchell ME, Tomita-Mitchell A.) PLoS One. 2020;15(1):e0227385 PMID: 31929557 PMCID: PMC6957190 SCOPUS ID: 2-s2.0-85077765307 01/14/2020

• Effect of endomyocardial biopsy on levels of donor-specific cell-free DNA.

  (Zangwill SD, Stamm KD, Hidestrand M, Tomita-Mitchell A, Mitchell ME.) J Heart Lung Transplant. 2019 10;38(10):1118-1120 PMID: 31324442 SCOPUS ID: 2-s2.0-85072281917 07/22/2019

• Human genotyping and an experimental model reveal NPR-C as a possible contributor to morbidity in coarctation of the aorta.

  (LaDisa JF Jr, Tomita-Mitchell A, Stamm K, Bazan K, Mahnke DK, Goetsch MA, Wegter BJ, Gerringer JW, Repp K, Palygin O, Zietara AP, Krolikowski MM, Eddinger TJ, Alli AA, Mitchell ME.) Physiol Genomics. 2019 06 01;51(6):177-185 PMID: 31002586 PMCID: PMC6620646 SCOPUS ID: 2-s2.0-85066457176 04/20/2019

• Metakaryotic cells linked to pediatric pulmonary vein stenosis.

  (Kirkpatrick EC, Mitchell ME, Thilly WG, Hidestrand P, Tomita-Mitchell A, Hidestrand M, Gostjeva EV.) Cardiovasc Pathol. 2019 Mar - Apr;39:51-53 PMID: 30660022 SCOPUS ID: 2-s2.0-85059952993 01/20/2019

• GSEPD: a Bioconductor package for RNA-seq gene set enrichment and projection display.

  (Stamm K, Tomita-Mitchell A, Bozdag S.) BMC Bioinformatics. 2019 Mar 06;20(1):115 PMID: 30841846 PMCID: PMC6404334 SCOPUS ID: 2-s2.0-85062495607 03/08/2019

• Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects.

  (Zhao Y, Guo T, Fiksinski A, Breetvelt E, McDonald-McGinn DM, Crowley TB, Diacou A, Schneider M, Eliez S, Swillen A, Breckpot J, Vermeesch J, Chow EWC, Gothelf D, Duijff S, Evers R, van Amelsvoort TA, van den Bree M, Owen M, Niarchou M, Bearden CE, Ornstein C, Pontillo M, Buzzanca A, Vicari S, Armando M, Murphy KC, Murphy C, Garcia-Minaur S, Philip N, Campbell L, Morey-Cañellas J, Raventos J, Rosell J, Heine-Suner D, Shprintzen RJ, Gur RE, Zackai E, Emanuel BS, Wang T, Kates WR, Bassett AS, Vorstman JAS, Morrow BE, International 22q11.2 Brain and Behavior Consortium.) Am J Med Genet A. 2018 10;176(10):2172-2181 PMID: 30289625 PMCID: PMC6209529 SCOPUS ID: 2-s2.0-85054522149 10/06/2018

• Noninvasive Assay for Donor Fraction of Cell-Free DNA in Pediatric Heart Transplant Recipients.

  (Ragalie WS, Stamm K, Mahnke D, Liang HL, Simpson P, Katz R, Tomita-Mitchell A, Kindel SJ, Zangwill S, Mitchell ME.) J Am Coll Cardiol. 2018 06 26;71(25):2982-2983 PMID: 29929623 SCOPUS ID: 2-s2.0-85048264947 06/23/2018

• Genome-Wide Association Study to Find Modifiers for Tetralogy of Fallot in the 22q11.2 Deletion Syndrome Identifies Variants in the GPR98 Locus on 5q14.3.

  (Guo T, Repetto GM, McDonald McGinn DM, Chung JH, Nomaru H, Campbell CL, Blonska A, Bassett AS, Chow EWC, Mlynarski EE, Swillen A, Vermeesch J, Devriendt K, Gothelf D, Carmel M, Michaelovsky E, Schneider M, Eliez S, Antonarakis SE, Coleman K, Tomita-Mitchell A, Mitchell ME, Digilio MC, Dallapiccola B, Marino B, Philip N, Busa T, Kushan-Wells L, Bearden CE, Piotrowicz M, Hawuła W, Roberts AE, Tassone F, Simon TJ, van Duin EDA, van Amelsvoort TA, Kates WR, Zackai E, Johnston HR, Cutler DJ, Agopian AJ, Goldmuntz E, Mitchell LE, Wang T, Emanuel BS, Morrow BE, International 22q11.2 Consortium/Brain and Behavior Consortium*.) Circ Cardiovasc Genet. 2017 Oct;10(5) PMID: 29025761 PMCID: PMC5647121 10/14/2017

• Impact of MYH6 variants in hypoplastic left heart syndrome.

  (Tomita-Mitchell A, Stamm KD, Mahnke DK, Kim MS, Hidestrand PM, Liang HL, Goetsch MA, Hidestrand M, Simpson P, Pelech AN, Tweddell JS, Benson DW, Lough JW, Mitchell ME.) Physiol Genomics. 2016 12 01;48(12):912-921 PMID: 27789736 PMCID: PMC5206387 SCOPUS ID: 2-s2.0-85006309110 10/30/2016