Staff Collaborate Conference Room

Gopika Senthilkumar

Gopika Senthilkumar

Gopika Senthilkumar

M2 Student

Locations

  • Medical Scientist Training Program

Contact Information

Education

BS, Biomedical Engineering, University of Wisconsin-Madison, 2019

Research Interests

Oncology, Cardiovascular physiology

Research Experience

University of Wisconsin, Madison, 2017-2019
Advisors: Dr. Randall Kimple, Dr. Andrew Baschnagel
Projects: 1. Inhibition of fibroblast growth factor receptor using AZD4547 radiosensitizes Head and Neck Cancer and Lung Cancer. 2. Autophagy's role in Head and Neck Cancer’s therapeutic resistance to radiation and cetuximab

University of Wisconsin, Madison, 2017-2019
Advisors: Dr. Fredrick Kelcz, Dr. Lonie Salkowski
Project: Novel needle guide for preoperative mammography-based wire guide localization of breast lesions

Morgride Institute for Research, 2017-2019
Advisors: Dr. Kevin Eliceiri
Project: Design and development of acoustic sound-based imaging technology for diagnosing objecting tinnitus

Massachusetts Institute of Technology, Summer 2018
Advisors: Matt Kressy
Project: Automated gait coaching system for overcoming running-related shin splints

University of Wisconsin, Madison, 2015-2016
Advisors: Dr. Gillian McLellan
Project: 3D reconstruction of retinal histology images to track patterns of ganglion cell loss.

University of Wisconsin, Madison - Department of Human Oncology, 2017-2019
Advisor: Dr. Randall Kimple, Dr. Andrew Baschnagel
Projects: 1. Inhibition of fibroblast growth factor receptor using AZD4547 radiosensitizes Head and Neck Cancer and Lung Cancer. 2. Autophagy's role in Head and Neck Cancer’s therapeutic resistance to radiation and cetuximab.

Publications

SenthilKumar G, Fisher MM, Skiba JH, et al. (2020). FGFR Inhibition Enhances Sensitivity to Radiation in Non-Small Cell Lung Cancer. Mol Cancer Ther, 19(6), 1255-1265. doi:10.1158/1535-7163.MCT-19-0931

Fisher MM, SenthilKumar G, Hu R, et al. (2020). Fibroblast Growth Factor Receptors as Targets for Radiosensitization in Head and Neck Squamous Cell Carcinomas. International Journal of Radiation Oncology, Biology, Physics. doi:10.1016/j.ijrobp.2020.03.040

Schlaak RA, SenthilKumar G, Boerma M, Bergom C. (2020). Advances in Preclinical Research Models of Radiation-Induced Cardiac Toxicity. Cancers (Basel), 12(2). doi:10.3390/cancers12020415

Schlaak RA, Frei A, SenthilKumar G, et al. (2020). Differences in Expression of Mitochondrial Complexes Due to Genetic Variants May Alter Sensitivity to Radiation-Induced Cardiac Dysfunction. Front Cardiovasc Med, 7, 23. doi:10.3389/fcvm.2020.00023

SenthilKumar G, Francis DM, Baschnagel, AM. (2019). Fibroblast growth factor receptor as therapeutic targets in head and neck squamous cell carcinomas. In Improving the Therapeutic Ratio in Head and Neck Cancer. (Vol. 6, pp. 235-262): Academic Press. Elsevier.

Francis DM, SenthilKumar G, Ko HC, Baschnagel AM. (2019). The MET receptor as a therapeutic target in head and neck squamous cell carcinomas. In Improving the Therapeutic Ratio in Head and Neck Cancer. (Vol. 6, pp. 263-280): Academic Press. Elsevier.

SenthilKumar G, Skiba JH, Kimple RJ. (2019). High-throughput quantitative detection of basal autophagy and autophagic flux using image cytometry. Biotechniques, 67(2), 70-73. doi:10.2144/btn-2019-0044

Meeting Abstracts

Senthilkumar G, Fernando D, Gamblin TC, et al. Validation of the AJCC 8th Edition Staging System for Appendiceal Cancer Using a Multi-institutional Cohort of Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC). American College of Surgeons Clinical Congress 2020. October 2020. [Oral Presentation]

Lee YS, Skiba J, Senthilkumar G, et al. Inhibition of radiation-induced autophagy improves control of head and neck squamous cell carcinoma. International Journal of Radiation Oncology Biology Physics. March 2020. Abstract 323. [Poster]

Senthilkumar G, Miller M, Fisher MM, et al. Radiosensitization of head and neck cancer by FGFR inhibition. American Association of Cancer Research 2019 Proceedings. Abstract 2929. April 2019. [Poster]

Miller M, Fisher MM, Senthilkumar G, et al. Evaluation of the pan-FGFR inhibitor AZD4547 with radiation in non-small cell lung cancer. American Association of Cancer Research 2019 Proceedings. Abstract 2924. April 2019. [Poster]

Eckers J, Skiba J, Senthilkumar G, et al. Autophagy contributed to therapeutic resistance in head and neck cancer. American Association of Cancer Research 2018 Proceedings. Abstract 1344. [Poster]

General Interests

Running, drawing/painting, boxing, trying new local restaurants, guitar