
Heather Himburg, PhD
Associate Professor, Radiation Oncology
Locations
- Radiation Oncology
Contact Information
Education
MS Biomedical Engineering, Ohio State University, Columbus, OH, 2001
PhD Biomedical Engineering, Duke University, Durham, NC, 2005
Biography
Training
Postdoctoral Fellow, Medicine, Cellular Therapy, Duke University, Durham, NC
Research Interests
Mitigation of hematopoietic acute radiation toxicity, role of the bone marrow microenvironment in regulating normal and malignant hematopoiesis, cancer stem cell biology
Publications
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(Fang T, Zhang Y, Chang VY, Roos M, Termini CM, Signaevskaia L, Quarmyne M, Lin PK, Pang A, Kan J, Yan X, Javier A, Pohl K, Zhao L, Scott P, Himburg HA, Chute JP.) Blood. 2020 Jul 23;136(4):441-454 PMID: 32369572 PMCID: PMC7378456 05/06/2020
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Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling.
(Himburg HA, Roos M, Fang T, Zhang Y, Termini CM, Schlussel L, Kim M, Pang A, Kan J, Zhao L, Suh H, Sasine JP, Sapparapu G, Bowers PM, Schiller G, Chute JP.) J Clin Invest. 2020 01 02;130(1):315-328 PMID: 31613796 PMCID: PMC6934217 10/16/2019
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PTPσ inhibitors promote hematopoietic stem cell regeneration.
(Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP.) Nat Commun. 2019 08 14;10(1):3667 PMID: 31413255 PMCID: PMC6694155 08/16/2019
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(Kim MM, Schlussel L, Zhao L, Himburg HA.) Radiat Res. 2019 07;192(1):53-62 PMID: 31081743 PMCID: PMC6668624 05/14/2019
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(Himburg HA, Termini CM, Schlussel L, Kan J, Li M, Zhao L, Fang T, Sasine JP, Chang VY, Chute JP.) Cell Stem Cell. 2018 09 06;23(3):370-381.e5 PMID: 30100167 PMCID: PMC6482945 08/14/2018
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Wild-type Kras expands and exhausts hematopoietic stem cells.
(Sasine JP, Himburg HA, Termini CM, Roos M, Tran E, Zhao L, Kan J, Li M, Zhang Y, de Barros SC, Rao DS, Counter CM, Chute JP.) JCI Insight. 2018 06 07;3(11) PMID: 29875320 PMCID: PMC6124423 06/08/2018
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Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms.
(Himburg HA, Doan PL, Quarmyne M, Yan X, Sasine J, Zhao L, Hancock GV, Kan J, Pohl KA, Tran E, Chao NJ, Harris JR, Chute JP.) Nat Med. 2017 01;23(1):91-99 PMID: 27918563 PMCID: PMC5592969 12/06/2016
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Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration.
(Yan X, Himburg HA, Pohl K, Quarmyne M, Tran E, Zhang Y, Fang T, Kan J, Chao NJ, Zhao L, Doan PL, Chute JP.) Cell Rep. 2016 11 01;17(6):1584-1594 PMID: 27806297 PMCID: PMC5963255 11/03/2016
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(Himburg HA, Grzybowski DM, Hazel AL, LaMack JA, Friedman MH.) J Biomech Eng. 2016 09 01;138(9) PMID: 27437909 PMCID: PMC4993249 07/21/2016
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A Molecular Profile of the Endothelial Cell Response to Ionizing Radiation.
(Himburg HA, Sasine J, Yan X, Kan J, Dressman H, Chute JP.) Radiat Res. 2016 08;186(2):141-52 PMID: 27387861 PMCID: PMC6016841 07/09/2016
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(Michelotti GA, Tucker A, Swiderska-Syn M, Machado MV, Choi SS, Kruger L, Soderblom E, Thompson JW, Mayer-Salman M, Himburg HA, Moylan CA, Guy CD, Garman KS, Premont RT, Chute JP, Diehl AM.) Gut. 2016 Apr;65(4):683-92 PMID: 25596181 PMCID: PMC4504836 01/18/2015
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Mammalian ToxicologyrnChapter 15: Ionizing Radiation: Toxicologic Actionrn
(Himburg HA, Chute JPrnEditor: Abou‐Donia Mohamed B..) . 02/27/2015