
Heather Himburg, PhD
Associate Professor, Radiation Oncology
Locations
- Radiation Oncology
Contact Information
Education
MS Biomedical Engineering, Ohio State University, Columbus, OH, 2001
PhD Biomedical Engineering, Duke University, Durham, NC, 2005
Biography
Training
Postdoctoral Fellow, Medicine, Cellular Therapy, Duke University, Durham, NC
Research Interests
Mitigation of hematopoietic acute radiation toxicity, role of the bone marrow microenvironment in regulating normal and malignant hematopoiesis, cancer stem cell biology
Publications
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(Zenga J, Awan MJ, Frei A, Petrie E, Sharma GP, Shreenivas A, Shukla M, Himburg HA.) Head Neck. 2022 06;44(6):1324-1334 PMID: 35261119 PMCID: PMC9081149 SCOPUS ID: 2-s2.0-85125920861 03/10/2022
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(Sharma GP, Fish BL, Frei AC, Narayanan J, Gasperetti T, Scholler D, Pierce L, Szalewski N, Blue N, Medhora M, Himburg HA.) Int J Radiat Oncol Biol Phys. 2022 05 01;113(1):177-191 PMID: 35093482 PMCID: PMC9018504 01/31/2022
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Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution.
(Termini CM, Pang A, Fang T, Roos M, Chang VY, Zhang Y, Setiawan NJ, Signaevskaia L, Li M, Kim MM, Tabibi O, Lin PK, Sasine JP, Chatterjee A, Murali R, Himburg HA, Chute JP.) Nat Commun. 2021 11 30;12(1):6990 PMID: 34848712 PMCID: PMC8635308 12/02/2021
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(Fish BL, MacVittie TJ, Gao F, Narayanan J, Gasperetti T, Scholler D, Sheinin Y, Himburg HA, Hart B, Medhora M.) Health Phys. 2021 10 01;121(4):419-433 PMID: 34546222 PMCID: PMC8577554 09/22/2021
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(Sharma GP, Frei AC, Narayanan J, Gasperetti T, Veley D, Amjad A, Albano K, Fish BL, Himburg HA.) PLoS One. 2021;16(10):e0259042 PMID: 34695155 PMCID: PMC8544859 10/26/2021
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(Fang T, Zhang Y, Chang VY, Roos M, Termini CM, Signaevskaia L, Quarmyne M, Lin PK, Pang A, Kan J, Yan X, Javier A, Pohl K, Zhao L, Scott P, Himburg HA, Chute JP.) Blood. 2020 07 23;136(4):441-454 PMID: 32369572 PMCID: PMC7378456 05/06/2020
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Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling.
(Himburg HA, Roos M, Fang T, Zhang Y, Termini CM, Schlussel L, Kim M, Pang A, Kan J, Zhao L, Suh H, Sasine JP, Sapparapu G, Bowers PM, Schiller G, Chute JP.) J Clin Invest. 2020 01 02;130(1):315-328 PMID: 31613796 PMCID: PMC6934217 10/16/2019
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PTPσ inhibitors promote hematopoietic stem cell regeneration.
(Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP.) Nat Commun. 2019 08 14;10(1):3667 PMID: 31413255 PMCID: PMC6694155 08/16/2019
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(Kim MM, Schlussel L, Zhao L, Himburg HA.) Radiat Res. 2019 07;192(1):53-62 PMID: 31081743 PMCID: PMC6668624 05/14/2019
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(Himburg HA, Termini CM, Schlussel L, Kan J, Li M, Zhao L, Fang T, Sasine JP, Chang VY, Chute JP.) Cell Stem Cell. 2018 09 06;23(3):370-381.e5 PMID: 30100167 PMCID: PMC6482945 08/14/2018
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Wild-type Kras expands and exhausts hematopoietic stem cells.
(Sasine JP, Himburg HA, Termini CM, Roos M, Tran E, Zhao L, Kan J, Li M, Zhang Y, de Barros SC, Rao DS, Counter CM, Chute JP.) JCI Insight. 2018 06 07;3(11) PMID: 29875320 PMCID: PMC6124423 06/08/2018
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Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms.
(Himburg HA, Doan PL, Quarmyne M, Yan X, Sasine J, Zhao L, Hancock GV, Kan J, Pohl KA, Tran E, Chao NJ, Harris JR, Chute JP.) Nat Med. 2017 01;23(1):91-99 PMID: 27918563 PMCID: PMC5592969 12/06/2016