
Kelly J. Henrickson, MD
Professor, Pediatrics (Infectious Diseases) and Microbiology & Immunology; Director, Midwest Respiratory Virus Program
Contact Information
Biography
General Interests
Negative strand respiratory virus molecular epidemiology and natural history
Education
MD, University of Washington, Seattle, 1984
Research Interests
I have been interested in molecular evolution, antigenic variation of surface glycoprotein’s, epidemiology and natural history of parainfluenza and influenza viruses and the development of rapid molecular diagnostic assays. My most recent awards from the NIAID include working on advances in molecular diagnostics for influenza subtyping (including avian and swine) (2006-2011), bioterrorism agents (2003-2012), and working on multiplex point of care diagnostic assays for community acquired respiratory viruses (2008-2014). Other funded research grants and contracts include a BARDA contract for evaluating influenza diagnostic assays (2010-2015) and the development of molecular diagnostic assays for community acquired pneumonia and sepsis including influenza virus type A and B. In addition my most recent work includes close collaborations with the NIH to describe the epidemiology and evolution of the 2009 pandemic H1N1 virus and extending the knowledge base for paramyxovirus genomic data (1st author on NIAID white paper-2010). My laboratory has developed more than a dozen multiplex molecular diagnostic assays to bioterrorism agents, viruses and respiratory pathogens.
Figure 1. Respiratory virus epidemiology in Southeast Wisconsin
Publications
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Establishment of a lethal aged mouse model of human respiratory syncytial virus infection.
(Zhang K, Li C, Luo YS, Wen L, Yuan S, Wang D, Ho-Yin Wong B, Zhao X, Chiu MC, Ye ZW, Sun Z, Zhao H, Zhang X, Hu M, Yang D, Shuai H, Wang Y, He J, Bose ME, Henrickson KJ, Huang JD, Zheng B, Chu H, Zhou J.) Antiviral Res. 2019 Jan;161:125-133.
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Simulated Respiratory Secretion for Use in the Development of Influenza Diagnostic Assays.
(Bose ME, McCaul KC, Mei H, Sasman A, He J, Kramp W, Shively R, Yan K, Henrickson KJ.) PLoS One. 2016;11(11):e0166800.
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Sequencing and analysis of globally obtained human respiratory syncytial virus A and B genomes.
(Bose ME, He J, Shrivastava S, Nelson MI, Bera J, Halpin RA, Town CD, Lorenzi HA, Noyola DE, Falcone V, Gerna G, De Beenhouwer H, Videla C, Kok T, Venter M, Williams JV, Henrickson KJ.) PLoS One. 2015;10(3):e0120098.
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(Zhang K, He J, Li C, Bose ME, Henrickson KJ, Zhou J, Zheng BJ.) Genome Announc. 2015 Mar 05;3(2).
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(Makari D, Staat MA, Henrickson KJ, Wu X, Ambrose CS.) Clin Pediatr (Phila). 2015 Jun;54(6):594-7.
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(Bose ME, Sasman A, Mei H, McCaul KC, Kramp WJ, Chen LM, Shively R, Williams TL, Beck ET, Henrickson KJ.) Influenza Other Respir Viruses. 2014 Jul;8(4):474-81.
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(Jafri HS, Wu X, Makari D, Henrickson KJ.) Pediatr Infect Dis J. 2013 Apr;32(4):335-40.
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(Beck ET, He J, Nelson MI, Bose ME, Fan J, Kumar S, Henrickson KJ.) PLoS One. 2012;7(9):e46048.
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Update on influenza diagnostics: lessons from the novel H1N1 influenza A pandemic.
(Kumar S, Henrickson KJ.) Clin Microbiol Rev. 2012 Apr;25(2):344-61.
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(Rebuffo-Scheer C, Bose M, He J, Khaja S, Ulatowski M, Beck ET, Fan J, Kumar S, Nelson MI, Henrickson KJ.) PLoS One. 2011;6(10):e25468.
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(Kumar S, Fan J, Melzer-Lange M, Trost J, Havens PL, Willoughby RE, Chusid MJ, Henrickson KJ.) Pediatr Emerg Care. 2011 Sep;27(9):804-7.
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(Nelson MI, Tan Y, Ghedin E, Wentworth DE, St George K, Edelman L, Beck ET, Fan J, Lam TT, Kumar S, Spiro DJ, Simonsen L, Viboud C, Holmes EC, Henrickson KJ, Musser JM.) J Virol. 2011 Jan;85(2):828-34.