Michael E. Mitchell, MD

Professor and Chief of the Division of Congenital Heart Surgery at the Medical College of Wisconsin; Medical Director of Cardiothoracic Surgery at Children's Wisconsin; Surgical Director of the Herma Heart Institute; and the S. Bert Litwin Chair in Cardiothoracic Surgery at Children's

Locations

Herma Heart Institute
9000 W. Wisconsin Ave.
Milwaukee, WI 53226

Biography

Dr. Mitchell is a Pediatric Cardiothoracic Surgeon at Children’s Wisconsin and performs all complex neonatal and pediatric cardiac surgery, as well as pediatric and adult heart and lung transplantation, and minimally invasive cardiac surgery. He was trained at Children’s Hospital of Philadelphia, Boston Children’s Hospital, and Brigham and Women’s Hospital.

Certifications

Congenital Cardiac Surgery
Thoracic and Cardiac Surgery
Surgery

Specialties

Pediatric Cardiac Surgery
Cardiothoracic Surgery
General Surgery

Languages

English

                
                    Research Experience
                
                    Bioengineered Heart Cells in Hypoplastic Left Heart Syndrome (HLHS)
Genetic Impact of MYH6 Variants
Highly Sensitive, Non-Invasive Cardiac Transplant Rejection
Total Cell-Free Deoxyribonucleic Acid (total of cf-DNA) Predictor

                    Clinical Expertise
                
                    Adult Congenital Cardiac Surgery
Cardiovascular Surgery
Heart, Lung and Heart/Lung Transplantation
Neonatal and Infant Cardiac Surgery
Tracheal Suspension
Valve Reconstruction

                    Leadership Positions
                
                    Board Member, Children's Specialty Group (CSG)
Board Member, United Network for Organ Sharing, Region 7 Regional Heart Review
Chair Person, American College of Cardiology (ACC), Congenital Program Committee
Co-Chair Children's Specialty Group (CSG) Quality Committee
Course Chair, American Association for Thoracic Surgery (AATS)/Society of Thoracic Surgeons (STS) Congenital Heart Disease Symposium
Director, Children's Hospital of Wisconsin (CHW) Tracheal Reconstruction Team
Member & Scientific Reviewer, US Dept. of Defense, Congressionally Directed Medical Research Programs (CDMRP)
Member & Scientific Reviewer, US Dept. of Defense, Medical Research Program (PRMRP)
Member & Scientific Reviewer, US Dept. of Defense, Pre-Congenital Heart Disease (Pre-CHD)
Member, American College of Cardiology (ACC), Section Leadership Council
Member, Children's Specialty Group (CSG) Finance Committee
Member, Congenital Heart Surgeons' Society (CHS), Standards & Ethics Committee

                    MCW Program / Core Facilities
                
                    ACGME Accredited Residency Pediatric Cardiothoracic Surgical Training Program
Advisory Committee, Pediatric Cardiology Research Fellow
Course Director, Pediatric Cardiothoracic Surgery Rotation
Course Director, Pediatric Cardiothoracic Surgery, Integrative Selective for Fourth Year Medical Sutdents
Member, Cardiovascular Scientific Advisory Committee
Member, DiGeorge Program Planning Committee
Member, Immunodeficiency Subcommittee
Program Director, ACGME Fellowship in Pediatric Cardiothoracic Surgery

                    Educational Expertise
                
                    1990 A.B. Princeton University, Chemistry (Cum Laude)
1995 M.D. Harvard Medical School (Magna Cum Laude)
2017 Harvard T.H. Chan School of Public Health, Leadership Development for Physicians in Academic Health Centers

                    Community Partnerships
                
                    Member, WI Statewide Umbrella Immunodeficiency Newborn Screening Subcomittee

Increase in nuclear cell-free DNA is associated with major adverse events in adult and pediatric heart transplant recipients.

(Zangwill SD, Deshpande SR, Simpson PM, Liang HL, Zhang L, Dasgupta M, Richmond ME, Kindel SJ, Bichell DP, Mahle WT, Wigger MA, Schroder JN, Knecht KR, Pahl E, Gaglianello NA, North PE, Tomita-Mitchell A, Mitchell ME.) Clin Transplant. 2022 Jan;36(1):e14509 PMID: 34649304 SCOPUS ID: 2-s2.0-85120575732 10/15/2021
Total Cell-Free DNA Predicts Death and Infection Following Pediatric and Adult Heart Transplantation.

(Scott JP, Ragalie WS, Stamm KD, Mahnke DK, Liang HL, Simpson PM, Dasgupta M, Katz R, North PE, Tomita-Mitchell A, Zangwill SD, Kindel SJ, Mitchell ME.) Ann Thorac Surg. 2021 10;112(4):1282-1289 PMID: 33039362 SCOPUS ID: 2-s2.0-85103701202 10/12/2020
Correction: Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease.

(Audain E, Wilsdon A, Breckpot J, Izarzugaza JMG, Fitzgerald TW, Kahlert AK, Sifrim A, Wünnemann F, Perez-Riverol Y, Abdul-Khaliq H, Bak M, Bassett AS, Benson DW, Berger F, Daehnert I, Devriendt K, Dittrich S, Daubeney PE, Garg V, Hackmann K, Hoff K, Hofmann P, Dombrowsky G, Pickardt T, Bauer U, Keavney BD, Klaassen S, Kramer HH, Marshall CR, Milewicz DM, Lemaire S, Coselli JS, Mitchell ME, Tomita-Mitchell A, Prakash SK, Stamm K, Stewart AFR, Silversides CK, Siebert R, Stiller B, Rosenfeld JA, Vater I, Postma AV, Caliebe A, Brook JD, Andelfinger G, Hurles ME, Thienpont B, Larsen LA, Hitz MP.) PLoS Genet. 2021 Sep;17(9):e1009809 PMID: 34547032 PMCID: PMC8454942 SCOPUS ID: 2-s2.0-85116272362 09/22/2021
Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease.

(Audain E, Wilsdon A, Breckpot J, Izarzugaza JMG, Fitzgerald TW, Kahlert AK, Sifrim A, Wünnemann F, Perez-Riverol Y, Abdul-Khaliq H, Bak M, Bassett AS, Benson DW, Berger F, Daehnert I, Devriendt K, Dittrich S, Daubeney PE, Garg V, Hackmann K, Hoff K, Hofmann P, Dombrowsky G, Pickardt T, Bauer U, Keavney BD, Klaassen S, Kramer HH, Marshall CR, Milewicz DM, Lemaire S, Coselli JS, Mitchell ME, Tomita-Mitchell A, Prakash SK, Stamm K, Stewart AFR, Silversides CK, Siebert R, Stiller B, Rosenfeld JA, Vater I, Postma AV, Caliebe A, Brook JD, Andelfinger G, Hurles ME, Thienpont B, Larsen LA, Hitz MP.) PLoS Genet. 2021 07;17(7):e1009679 PMID: 34324492 PMCID: PMC8354477 SCOPUS ID: 2-s2.0-85111770757 07/30/2021
Outcomes Following Surgery to Address Shone Syndrome in Children.

(Dalton TJ, Johnson WK, Kuhn EM, Goot BH, Woods RK, Mitchell ME, Hraska V.) World J Pediatr Congenit Heart Surg. 2021 05;12(3):360-366 PMID: 33942685 05/05/2021
Roadmap for Ross procedure: Staged strategy.

(Hraska V, Mitchell ME, Woods RK.) J Thorac Cardiovasc Surg. 2021 Jan 13 PMID: 33581898 02/15/2021
Pulmonary Vein Stenosis: Moving From Past Pessimism to Future Optimism.

(McLennan DI, Solano ECR, Handler SS, Lincoln J, Mitchell ME, Kirkpatrick EC.) Front Pediatr. 2021;9:747812 PMID: 34676188 PMCID: PMC8524035 SCOPUS ID: 2-s2.0-85117473817 10/23/2021
Association of atrial septal fenestration with outcomes after atrioventricular septal defect repair

(Callahan CP, Jegatheeswaran A, Barron DJ, Husain SA, Fuller S, Overman DM, McCrindle BW, Blackstone EH, Caldarone CA, Dabal RJ, DeCampli WM, Eghtesady P, Honjo O, Jacobs JP, Kirklin JK, Mitchell ME, Nelson JS, Paramananthan T, Phillips A, Polimenakos AC, Toth AJ, Ramakrishan K, Rajeswaran J, Turek JW.) Journal of Thoracic and Cardiovascular Surgery. 2021 SCOPUS ID: 2-s2.0-85116755917 01/01/2021
Comparison of Patch Materials for Pulmonary Artery Reconstruction.

(Ebert N, McGinnis M, Johnson W, Kuhn EM, Mitchell ME, Tweddell JS, Woods RK.) Semin Thorac Cardiovasc Surg. 2021 Summer;33(2):459-465 PMID: 32977008 PMCID: PMC7985045 SCOPUS ID: 2-s2.0-85092719240 09/26/2020
Nitric oxide added to the sweep gas of the oxygenator during cardiopulmonary bypass in infants: A pilot randomized controlled trial.

(Niebler RA, Chiang-Ching H, Daley K, Janecke R, Jobe SM, Mitchell ME, Varner C, Woods K, Scott JP.) Artif Organs. 2021 Jan;45(1):22-28 PMID: 32737900 SCOPUS ID: 2-s2.0-85090452040 08/02/2020
Use of Metformin in Pulmonary Vein Stenosis after TAPVR Repair.

(Kirkpatrick EC, Mitchell ME, Thilly WG, Cava J, Tomita-Mitchell A, Gostjeva EV.) Glob Pediatr Health. 2020;7:2333794X20958924 PMID: 33029553 PMCID: PMC7522838 10/09/2020
Commentary: A long haul and a short slide?

(Mitchell ME.) Journal of Thoracic and Cardiovascular Surgery. September 2020;160(3):807-808 SCOPUS ID: 2-s2.0-85087010269 09/01/2020

Michael E. Mitchell, MD

Michael E. Mitchell, MD

Professor and Chief of the Division of Congenital Heart Surgery at the Medical College of Wisconsin; Medical Director of Cardiothoracic Surgery at Children's Wisconsin; Surgical Director of the Herma Heart Institute; and the S. Bert Litwin Chair in Cardiothoracic Surgery at Children's

Locations

Biography

Research Experience

Clinical Expertise

Leadership Positions

MCW Program / Core Facilities

Educational Expertise

Community Partnerships

Publications