Michael T. Zimmermann, PhD

Publications

• Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses.

  (Chen Y, Yang M, Huang W, Chen W, Zhao Y, Schulte ML, Volberding P, Gerbec Z, Zimmermann MT, Zeighami A, Demos W, Zhang J, Knaack DA, Smith BC, Cui W, Malarkannan S, Sodhi K, Shapiro JI, Xie Z, Sahoo D, Silverstein RL.) Circ Res. 2019 Dec 06;125(12):1087-1102 PMID: 31625810 PMCID: PMC6921463 SCOPUS ID: 2-s2.0-85076330129 10/19/2019

• Novel biallelic variants in associated with mitochondrial myopathy.

  (Schultz-Rogers L, Ferrer A, Dsouza NR, Zimmermann MT, Smith BE, Klee EW, Dhamija R.) Cold Spring Harb Mol Case Stud. 2019 Dec;5(6) PMID: 31604776 PMCID: PMC6913144 SCOPUS ID: 2-s2.0-85076504636 10/13/2019

• Genetic variants in DGAT1 cause diverse clinical presentations of malnutrition through a specific molecular mechanism.

  (Gupta A, Dsouza NR, Zarate YA, Lombardo R, Hopkin R, Linehan AR, Simpson J, McCarrier J, Agre KE, Gavrilova RH, Stephens MC, Grothe RM, Monaghan KG, Xie Y, Basel D, Urrutia RA, Cole CR, Klee EW, Zimmermann MT.) Eur J Med Genet. 2019 Nov 25:103817 PMID: 31778854 SCOPUS ID: 2-s2.0-85076241133 11/30/2019

• Modeling post-translational modifications and cancer-associated mutations that impact the heterochromatin protein 1α-importin α heterodimers.

  (Zimmermann MT, Williams MM, Klee EW, Lomberk GA, Urrutia R.) Proteins. 2019 Nov;87(11):904-916 PMID: 31152607 PMCID: PMC6790107 SCOPUS ID: 2-s2.0-85067403924 06/04/2019

• Molecular characterization of known and novel ACVR1 variants in phenotypes of aberrant ossification.

  (Gupta A, Zimmermann MT, Wang H, Broski SM, Sigafoos AN, Macklin SK, Urrutia RA, Clark KJ, Atwal PS, Pignolo RJ, Klee EW.) Am J Med Genet A. 2019 Sep;179(9):1764-1777 PMID: 31240838 SCOPUS ID: 2-s2.0-85068139246 06/27/2019

• Recurrent mutations in ALK-negative anaplastic large cell lymphoma.

  (Luchtel RA, Zimmermann MT, Hu G, Dasari S, Jiang M, Oishi N, Jacobs HK, Zeng Y, Hundal T, Rech KL, Ketterling RP, Lee JH, Eckloff BW, Yan H, Gaonkar KS, Tian S, Ye Z, Kadin ME, Sidhu J, Jiang L, Voss J, Link BK, Syrbu SI, Facchetti F, Bennani NN, Slager SL, Ordog T, Kocher JP, Cerhan JR, Ansell SM, Feldman AL.) Blood. 2019 06 27;133(26):2776-2789 PMID: 31101622 PMCID: PMC6598380 SCOPUS ID: 2-s2.0-85069235121 05/19/2019

• A case of Coffin-Siris syndrome with severe congenital heart disease and a novel variant.

  (Dsouza NR, Zimmermann MT, Geddes GC.) Cold Spring Harb Mol Case Stud. 2019 Jun;5(3) PMID: 31160358 PMCID: PMC6549553 SCOPUS ID: 2-s2.0-85067212433 06/05/2019

• Aurora kinase B-phosphorylated HP1α functions in chromosomal instability.

  (Williams MM, Mathison AJ, Christensen T, Greipp PT, Knutson DL, Klee EW, Zimmermann MT, Iovanna J, Lomberk GA, Urrutia RA.) Cell Cycle. 2019 Jun;18(12):1407-1421 PMID: 31130069 PMCID: PMC6592258 SCOPUS ID: 2-s2.0-85067316375 05/28/2019

• X-Linked Lymphoproliferative Syndrome Presenting as Adult-Onset Multi-Infarct Dementia.

  (Blackburn PR, Lin WL, Miller DA, Lorenzo-Betancor O, Edwards ES, Zimmermann MT, Farrugia LP, Freeman WD, Soto AI, Walton RL, Klee EW, Atwal PS, Abraham RS, Billadeau DD, Ross OA, Dickson DW, Meschia JF.) J Neuropathol Exp Neurol. 2019 May 01;78(5):460-466 PMID: 30990878 PMCID: PMC6467195 SCOPUS ID: 2-s2.0-85064977307 04/17/2019

• Molecular modeling of LDLR aids interpretation of genomic variants.

  (Klee EW, Zimmermann MT.) J Mol Med (Berl). 2019 Apr;97(4):533-540 PMID: 30778614 PMCID: PMC6440939 SCOPUS ID: 2-s2.0-85061714006 02/20/2019

• Predict drug sensitivity of cancer cells with pathway activity inference.

  (Wang X, Sun Z, Zimmermann MT, Bugrim A, Kocher JP.) BMC Med Genomics. 2019 01 31;12(Suppl 1):15 PMID: 30704449 PMCID: PMC6357358 SCOPUS ID: 2-s2.0-85060845256 02/02/2019

• RITAN: rapid integration of term annotation and network resources.

  (Zimmermann MT, Kabat B, Grill DE, Kennedy RB, Poland GA.) PeerJ. 2019;7:e6994 PMID: 31355053 PMCID: PMC6644632 07/30/2019