
Shyam S. Chaurasia, MSc, PhD
Associate Professor
Locations
- EI 827
Contact Information
Education
Master of Science (MSc), Biochemistry
Bachelor of Science (BSc), Biochemistry
Biography
Dr. Shyam S. Chaurasia was born in Gwalior, also described as the “The Medieval Majestic Indian City with Music in its Soul.” He received his bachelor’s and master’s degrees in Science with Biochemistry as his major from the esteemed Nagpur University. He obtained a PhD degree from a globally ranked School of Life Sciences, Devi Ahilya University, Indore, India. He was awarded the prestigious Department of Biotechnology sponsored Postdoctoral Fellowship, and completed his Postdoctoral training in ophthalmology/neurosciences from Emory University, Atlanta, GA.
Dr. Chaurasia took his first faculty appointment in 2006 as a scientist at the Cole Eye Institute, Cleveland Clinic, Cleveland, OH. In 2009, he decided to move to Singapore and joined the Singapore Eye Research Institute, Singapore, and Institute of Molecular and Cellular Biology, A*STAR agency as an extramurally funded principal scientist/investigator. Later, he decided to return to the United States and took his first academic appointment as Assistant Professor on a tenure-track and successfully launched NIH/NEI-funded “Ocular Immunology & Angiogenesis Lab,” studying basic and translational research in vision sciences at the University of Missouri, Columbia, MO. In 2021, he joined as an associate professor in the Department of Ophthalmology and Visual Sciences/Eye Institute at MCW.
Honors and Awards
2019, Electron Microscopy Excellence Award, University of Missouri, Columbia, MO
2018, Appeared on the local NBC News Channel in the Prime Time News, KOMU News Channel (NBC channel affiliate), Columbia, MO
2017, Electron Microscopy Excellence Award, University of Missouri, Columbia, MO
2011, Outstanding Young Research Award, Singapore Eye Research Institute, Singapore
2007, Association for Research in Vision and Ophthalmology (ARVO) Travel Award, ARVO, Rockville, MD
2006, Pineal Cell Biology Travel Award, Gordon Research Conferences, Buellton, CA
2005, X European Pineal and Biological Rhythm Society Congress Travel Award, European Pineal and Biological Rhythm Society Congress Travel Award, Frankfurt, Germany
2004, Pineal Cell Biology Travel Award, Gordon Research Conferences, Oxford, UK
2003, Mentor, BRAIN Summer Research Program, Center for Behavioral Neuroscience, Emory University, Atlanta, GA
Research Interests
Dr. Chaurasia’s Ocular Immunology and Angiogenesis Lab is funded by NIH/NEI and focuses on the Molecular Basis of Eye Diseases for the development of a highly innovative basic and translational multidisciplinary research program in the identification and validation of novel biomarkers and targets, and evaluate potential VEGF-independent Next-Generation Precision therapeutics/Medicine to treat Ocular Fibrotic and Angiogenic Diseases (OFADs). Dr. Chaurasia has substantial experience in basic and translational vision sciences, as evident from published more than 100 peer-reviewed research papers and 150+ scientific abstracts and presentations at the national and international level.
Research Experience
- Diabetic Retinopathy & Diabetic Macular Edema
- Age-related Macular Degeneration
- Retinopathy of Prematurity
- Fibrotic Eye Diseases
- Nanomedicine & Wound healing therapeutics in the Eye
- Next-Gen Tools in Precision Medicine for Retinal Degenerative Diseases
- Countermeasures Against Chemical Threats (CounterACT)
Publications
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Decorin regulates collagen fibrillogenesis during corneal wound healing in mouse in vivo.
(Gupta S, Buyank F, Sinha NR, Grant DG, Sinha PR, Iozzo RV, Chaurasia SS, Mohan RR.) Exp Eye Res. 2022 03;216:108933 PMID: 35031282 PMCID: PMC8885890 SCOPUS ID: 2-s2.0-85123350225 01/16/2022
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Damage-Associated Molecular Patterns (DAMPs) in Retinal Disorders.
(Mahaling B, Low SWY, Beck M, Kumar D, Ahmed S, Connor TB, Ahmad B, Chaurasia SS.) Int J Mol Sci. 2022 Feb 26;23(5) PMID: 35269741 PMCID: PMC8910759 03/11/2022
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Damage-Associated Molecular Patterns (DAMPs) in Retinal Disorders
(Mahaling B, Low SWY, Beck M, Kumar D, Ahmed S, Connor TB, Ahmad B, Chaurasia SS.) International Journal of Molecular Sciences. March-1 2022;23(5) SCOPUS ID: 2-s2.0-85125395177 03/01/2022
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Decorin Concentrations in Aqueous Humor of Patients with Diabetic Retinopathy.
(Low SWY, Vaidya T, Gadde SGK, Mochi TB, Kumar D, Kassem IS, Costakos DM, Ahmad B, Sethu S, Ghosh A, Chaurasia SS.) Life (Basel). 2021 Dec 17;11(12) PMID: 34947953 PMCID: PMC8707400 SCOPUS ID: 2-s2.0-85122401745 12/25/2021
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Small Leucine-Rich Proteoglycans (SLRPs) in the Retina.
(Low SWY, Connor TB, Kassem IS, Costakos DM, Chaurasia SS.) Int J Mol Sci. 2021 Jul 07;22(14) PMID: 34298915 PMCID: PMC8305803 SCOPUS ID: 2-s2.0-85109111419 07/25/2021
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Glutathione is a potential therapeutic target for acrolein toxicity in the cornea.
(Gupta S, Kamil S, Sinha PR, Rodier JT, Chaurasia SS, Mohan RR.) Toxicol Lett. 2021 Apr 01;340:33-42 PMID: 33421550 SCOPUS ID: 2-s2.0-85099361849 01/10/2021
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Collagen matrix perturbations in corneal stroma of Ossabaw mini pigs with type 2 diabetes.
(Sinha NR, Balne PK, Bunyak F, Hofmann AC, Lim RR, Mohan RR, Chaurasia SS.) Mol Vis. 2021;27:666-678 PMID: 35002212 PMCID: PMC8684810 SCOPUS ID: 2-s2.0-85123341839 01/11/2022
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(Tripathi R, Balne PK, Sinha NR, Martin LM, Kamil S, Landreneau JR, Gupta S, Rodier JT, Sinha PR, Hesemann NP, Hofmann AC, Fink MK, Chaurasia SS, Mohan RR.) Transl Vis Sci Technol. 2020 11;9(12):6 PMID: 33200047 PMCID: PMC7645241 11/18/2020
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A rabbit model for evaluating ocular damage from acrolein toxicity in vivo.
(Gupta S, Fink MK, Martin LM, Sinha PR, Rodier JT, Sinha NR, Hesemann NP, Chaurasia SS, Mohan RR.) Ann N Y Acad Sci. 2020 11;1480(1):233-245 PMID: 33067838 SCOPUS ID: 2-s2.0-85097112841 10/18/2020
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MicroRNA-15b Targets VEGF and Inhibits Angiogenesis in Proliferative Diabetic Retinopathy.
(Yang Y, Liu Y, Li Y, Chen Z, Xiong Y, Zhou T, Tao W, Xu F, Yang H, Ylä-Herttuala S, Chaurasia SS, Adam WC, Yang K.) J Clin Endocrinol Metab. 2020 11 01;105(11) PMID: 32797181 PMCID: PMC7947967 SCOPUS ID: 2-s2.0-85090881068 08/17/2020
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NOD-like Receptors in the Eye: Uncovering Its Role in Diabetic Retinopathy.
(Lim RR, Wieser ME, Ganga RR, Barathi VA, Lakshminarayanan R, Mohan RR, Hainsworth DP, Chaurasia SS.) Int J Mol Sci. 2020 Jan 30;21(3) PMID: 32019187 PMCID: PMC7037099 SCOPUS ID: 2-s2.0-85078978494 02/06/2020
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(Lim RR, Vaidya T, Gadde SG, Yadav NK, Sethu S, Hainsworth DP, Mohan RR, Ghosh A, Chaurasia SS.) Diabetes Metab Syndr. 2019 Mar - Apr;13(2):1581-1589 PMID: 31336525 SCOPUS ID: 2-s2.0-85063032614 07/25/2019