
Ashish Gadicherla, PhD
Assistant Professor, Director, Oxford Instruments Center for Advanced Microscopy, EM Core Facility Interim Technical Director, Structural Biology Shared Resources, MCW Cancer Center
Locations
- Cell Biology, Neurobiology & Anatomy
Contact Information
Education
Marie Curie Postdoctoral Fellow, Cardiac Physiology and Imaging, Oslo University, Oslo, Norway
PhD in Biotechnology, Cardiac Physiology, Ghent University, Ghent, Belgium
Master of Science in Biological Sciences, Purdue University, Indiana
Bachelor of Technology, Biotechnology, JN Technological University, Hyderabad, India
Biography
I started my scientific career with Bachelor’s degree in biotechnology which was a perfect combination of engineering and biological sciences. Because of my interest in biology, I followed that up with my Masters in biological sciences at Purdue University. For a few following years, I worked at the Medical College of Wisconsin studying the role of mitochondrial respiratory complexes and ion channels in the lab of Dr. David Stowe and Dr. Amadou Camara.
I then went on to obtain my PhD from Ghent University, Belgium studying the role of mitochondrial Connexin 43 channels in cardiac ischemia reperfusion injury. As a part of these studies, I worked in the lab of Dr. Wai-Meng Kwok to use planar lipid bilayer electrophysiology technique to verify channel identity and its characteristics. Marie Curie Postdoctoral fellowship enabled me to study the role of microRNAs and extracellular matrix proteins in cardiac fibrosis at Oslo University, Norway. I then went on to do a second postdoctoral fellowship in structural biology at the Max Planck Institute for Biophysics where I was involved in the determination of structure of sodium and potassium gated ion channels with the help of cryo-electron tomography.
Throughout my scientific career, an underlying theme has been the use of different imaging modalities including confocal imaging, super resolution imaging and later electron microscopy including cryoEM. As the director of Oxford Instruments Center for Advanced Imaging- EM Core, and the Interim Technical Director of the Structural Biology Shared Resources, I am involved in supporting researchers’ imaging needs from optical imaging to cryoEM where I can use my knowledge and experience to understand their imaging needs and help them in this endeavor.
Publications
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(Ch S, Lim RR, Low SWY, Grant DG, Patterson S, Ramasubramanian A, Gadicherla AK, Chaurasia SS.) Front Cell Dev Biol. 2025;13:1586029 PMID: 40510741 PMCID: PMC12158942 SCOPUS ID: 2-s2.0-105007973588 06/13/2025
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(Panajotov J, Falkenhagen A, Gadicherla AK, Johne R.) Virus Res. 2024 Jun;344:199364 PMID: 38522562 PMCID: PMC10995862 SCOPUS ID: 2-s2.0-85189026656 03/25/2024
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(Binsker U, Deneke C, Hamid HM, Gadicherla AK, Göhler A, Käsbohrer A, Hammerl JA.) ISME Commun. 2024 Jan;4(1):ycae126 PMID: 39526133 PMCID: PMC11546641 11/14/2024
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First purported images of ciguatoxin-3C by cryogenic and transmission electron microscopy
(Loeffler CR, Gadicherla A.) Journal of Molecular Structure. 15 January 2024;1296 SCOPUS ID: 2-s2.0-85174031695 01/15/2024
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(Valusenko-Mehrkens R, Gadicherla AK, Johne R, Falkenhagen A.) Int J Mol Sci. 2023 Mar 16;24(6) PMID: 36982745 PMCID: PMC10054668 SCOPUS ID: 2-s2.0-85151111064 03/30/2023
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(Singh AV, Katz A, Maharjan RS, Gadicherla AK, Richter MH, Heyda J, Del Pino P, Laux P, Luch A.) Sci Total Environ. 2023 Feb 20;860:160503 PMID: 36442637 PMCID: PMC9691506 SCOPUS ID: 2-s2.0-85143870010 11/29/2022
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(Hammerl JA, El-Mustapha S, Bölcke M, Trampert H, Barac A, Jäckel C, Gadicherla AK, Hertwig S.) Int J Mol Sci. 2022 Jun 17;23(12) PMID: 35743219 PMCID: PMC9224151 SCOPUS ID: 2-s2.0-85132137361 06/25/2022
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Monitoring and imaging pH in biofilms utilizing a fluorescent polymeric nanosensor.
(Kromer C, Schwibbert K, Gadicherla AK, Thiele D, Nirmalananthan-Budau N, Laux P, Resch-Genger U, Luch A, Tschiche HR.) Sci Rep. 2022 Jun 14;12(1):9823 PMID: 35701457 PMCID: PMC9197968 SCOPUS ID: 2-s2.0-85132050294 06/15/2022
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Phage vB_YenS_P400, a Novel Virulent Siphovirus of Yersinia enterocolitica Isolated from Deer
(Hammerl JA, Barac A, Jäckel C, Fuhrmann J, Gadicherla A, Hertwig S.) Microorganisms. August 2022;10(8) SCOPUS ID: 2-s2.0-85137323611 08/01/2022
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(Schilling-Loeffler K, Viera-Segura O, Corman VM, Schneider J, Gadicherla AK, Schotte U, Johne R.) Microorganisms. 2021 Nov 05;9(11) PMID: 34835427 PMCID: PMC8624179 11/28/2021
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Properties of two broad host range phages of yersinia enterocolitica isolated from wild animals
(Hammerl JA, Barac A, Erben P, Fuhrmann J, Gadicherla A, Kumsteller F, Lauckner A, Müller F, Hertwig S.) International Journal of Molecular Sciences. November-1 2021;22(21) SCOPUS ID: 2-s2.0-85117362740 11/01/2021
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(Singh AV, Maharjan RS, Jungnickel H, Romanowski H, Hachenberger YU, Reichardt P, Bierkandt F, Siewert K, Gadicherla A, Laux P, Luch A.) ACS Sustainable Chemistry and Engineering. 6 September 2021;9(35):11724-11737 SCOPUS ID: 2-s2.0-85114456525 09/06/2021