header-logo
AdobeStock_214253348
Cell Biology, Neurobiology and Anatomy (CBNA)
Brian Lin, PhD

Brian L. Lin, PhD

Assistant Professor

Locations

  • Cell Biology, Neurobiology and Anatomy

Contact Information

Education

Postdoctoral Fellow, Johns Hopkins Medical Institutions, 2023
PhD, Loyola University, 2016
BS, Miami University, 2008

Biography

Brian Lin started his research career in marine biology during his undergraduate studies at Miami University, where Brian also studied skeletal muscle in birds and amphibians. After graduating in 2008, Brian worked as a behavioral neuroscience technician at Cincinnati Children's Hospital and Northwestern University. From 2011-2016, Brian studied cell and molecular physiology at Loyola University Chicago focusing on the role of skeletal muscle myofilament proteins in the lab of Sakthivel Sadayappan. From 2016-2023, Brian studied the role of TRP channels in heart and kidney disease in the lab of David Kass in the Division of Cardiology at Johns Hopkins. From that work, Brian focused on the role of TRPC6 in the context of Duchenne muscular dystrophy for which he was awarded a K99/R00 award. Brian started his independent lab in the Department of Cell Biology, Neurobiology, and Anatomy at the Medical College of Wisconsin, where he continues to study novel therapeutics targeting TRP channels to treat dystrophic cardiomyopathy.

View Brian's lab page

Research Interests

We study mechanical signaling in the heart in the context of muscular dystrophy. These diseases are commonly associated with skeletal muscle dysfunction, such as severe muscle weakness and the loss of the ability to walk. Our focus is on the damage to the heart, because most patients with muscular dystrophy die from heart failure.

Our lab applies spatial transcriptomics, animal models of heart disease, single cardiomyocyte biomechanics, in silico drug discovery, nanoparticle drug delivery, and human stem cell engineering platforms to enable testing and screening of exciting new therapies to treat muscular dystrophy and beyond.


Publications

Publications of Brian L. Lin PhD from the Faculty Collaboration Database

© 2026 Medical College of Wisconsin.  All rights reserved.  | Terms and Privacy | Web Accessibility Statement

Non-Discrimination, Anti-Harassment, and Legal Compliance Statement
The Medical College of Wisconsin (MCW) is committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, military status, or other legally protected classification. MCW maintains full compliance with all applicable federal, state, and local laws and regulations in pursuit of our missions. Consistent with federal guidance, we affirm our commitment to individual merit, fairness, and equal treatment in all aspects of academic and institutional decision-making.

MCW's policies, federal and state laws, and regulations prohibit unlawful discrimination and harassment. Employees, learners, students, applicants, or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.