Center for Imaging Research

Center for Imaging Research (CIR)

Advanced Neuroimaging

Quantitative Susceptibility Mapping (QSM)

Quantitative Susceptibility Mapping (QSM)Quantitative Susceptibility Mapping (QSM) reconstruction is a challenging inverse problem driven by poor conditioning of the field to susceptibility transformation. State-of-art QSM reconstruction methods either suffer from image artifacts or long computation times, which limits QSM clinical translation efforts. To overcome these limitations, a deep-learning-based approach is proposed and demonstrated. An encoder-decoder neural network was trained to infer susceptibility maps on volume parcellated regions. The training data consisted of fabricated susceptibility distributions modeled to mimic the spatial frequency patterns of in-vivo brain susceptibility distributions. Inferred volume parcels were recombined to form composite QSM. This approach is denoted as ASPEN, standing for Approximated Susceptibility through Parcellated Encoder-decoder Networks. ASPEN performance was evaluated relative to…..

QSM reconstruction is a challenging inverse problem driven by poor conditioning of the field to susceptibility transformation. State-of-art QSM reconstruction methods either suffer from image artifacts or long computation times, which limits QSM clinical translation efforts. To overcome these limitations, a deep-learning-based approach is proposed and demonstrated.


Quantitative Susceptibility Mapping after Sports-related Concussion