Hu Yang, PhD
Kern Professor and Chair, Marquette-MCW Joint Department of Biomedical Engineering; MCW Department of Ophthalmology & Visual Sciences
Locations
- Biomedical Engineering
- TBRC C-2855
8701 Watertown Plank Rd.
Milwaukee, WI 53226
Contact Information
Education
PhD, Chemical Engineering, The University of Akron, Akron, Ohio, 2004
BE, Polymer, Sichuan University, Chengdu, China, 1998
Biography
Dr. Yang’s research focuses on biomaterials, nanomedicine, drug and gene delivery, and translational biomedical engineering. His work has advanced the development of dendrimer-based platforms, hydrogels, nanoparticles, and ocular drug delivery systems for the treatment of glaucoma, cancer, atherosclerosis, neurological disorders, and other diseases. His laboratory integrates materials engineering, pharmaceutical sciences, and biomedical applications to design targeted and sustained-release therapeutic systems.
Over the course of his career, Dr. Yang has received more than $24 million in research support as principal investigator, co-principal investigator, or co-investigator from agencies including the National Institutes of Health, National Science Foundation, U.S. Department of Agriculture, U.S. Environmental Protection Agency, and private foundations.
Dr. Yang has authored more than 120 peer-reviewed publications, book chapters, and review articles, and he is an inventor on multiple issued U.S. patents related to nanogels, antiglaucoma drug delivery, and polymer-based drug delivery systems. His research contributions have been recognized by honors including the NSF CAREER Award, the Wallace Coulter Foundation Translational Research Young Investigator Award, the Qimonda Endowed Chair, the Linda and Bipin Doshi Endowed Chair, and the Dr. Robert D. and Dr. Patricia E. Kern Professorship.
He has been ranked among the top two percent of the world’s most cited scientists in biomedical engineering & pharmacology & pharmacy for career-long impact according to the Stanford University Report since 2019. Beyond research, he has served as associate editor or editorial board member for multiple biomedical engineering journals and routinely serves on study sections for NIH.
Dr. Yang directs the Drug & Gene Delivery Laboratory at the Marquette-MCW Joint Department of Biomedical Engineering. His current research interests include ocular drug delivery, dendrimer-based nanomedicine, targeted drug and gene delivery, biomaterials, and translational nanoparticle platforms.
Learn more about the Drug & Gene Delivery Lab
Honors and Awards
Distinguished Alumni Award, Department of Chemical, Biomolecular, and Corrosion Engineering, The University of Akron, 2023.
Outstanding Editorial Board Member, Research, A Science Partner Journal, 2023.
Linda and Bipin Doshi Endowed Chair, Missouri S&T, 2020–2025.
Top 2% World’s Most Cited Scientists in Biomedical Engineering & Pharmacology & Pharmacy for Career-Long Impact, Stanford University Report, since 2019.
Qimonda Endowed Chair, College of Engineering, Virginia Commonwealth University, 2010–2020.
National Science Foundation CAREER Award, 2010.
Wallace Coulter Foundation Translational Research Young Investigator Award, 2009.
Outstanding Graduate Student Travel Award, The Society for Biomaterials, Memphis, TN, 2005.
Student Travel Award, ISPE Annual Conference, Las Vegas, NV, 2001.
P&G Award for Academic Excellence, Sichuan University, 1997.
Academic Excellence Award, Sichuan University, 1995 & 1996.
Patents:
Hu Yang, Da Huang, Method for continuous fabrication of multi-functional nanogels, US Patent 11,925,705, Issued 03/12/2024.
Juan Wang, Hu Yang, An ionic liquid pilocarpine analog as antiglaucoma drug, US Patent 11,845,741, Issued 12/19/2023.
Hu Yang, Shobha Ghosh, Hongliang He, Michael Lancina, Carbohydrate-functionalized nanoparticles and uses thereof, US Patent 11,801,309, Issued 10/31/2023
Yan Zhang, Hu Yang, Dana Selley, William Dewey, Hamid Akbarali, Nanoparticle conjugated synthetic opioid prodrugs and methods of their use, US Patent 11,590,241, Issued 02/28/2023.
Hu Yang, Olga Yu. Zolotarskaya, Kenneth J. Wynne, Kristoffer Valerie, Clickable polyoxetane carrier for drug delivery, US Patent 9,421,276, Issued 08/23/2016.
-Madison, John W. Kao).
Research Interests
- Drug Delivery Systems
- Gene Transfer Techniques
- Nanomedicine
Publications
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(Chuang HY, Huang D, Qi L, Singh V, Chernatynskaya A, Huang YW, Yang H.) ACS Appl Mater Interfaces. 2025 Jun 11;17(23):33439-33450 PMID: 40456699 PMCID: PMC12700075 SCOPUS ID: 2-s2.0-105007512700 06/03/2025
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(Qi L, Huang D, Kou H, Chernatynskaya A, Ercal N, Yang H.) Biomacromolecules. 2025 May 12;26(5):2986-2995 PMID: 40190197 PMCID: PMC12633722 SCOPUS ID: 2-s2.0-105002022355 04/07/2025
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(Kou H, Wang J, Yannie PJ, Huang D, Korzun WJ, Kakiyama G, Ghosh SS, Yang H.) ACS Pharmacol Transl Sci. 2025 May 09;8(5):1359-1365 PMID: 40370995 PMCID: PMC12070320 05/15/2025
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(Kou H, Qi L, Huang D, Wu J, Shi H, Yang H.) ACS Appl Mater Interfaces. 2025 Apr 30;17(17):24953-24962 PMID: 40237537 PMCID: PMC12633720 SCOPUS ID: 2-s2.0-105004055270 04/16/2025
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(Cooper RC, Wang J, Yang H.) Biomacromolecules. 2024 Sep 09;25(9):5928-5937 PMID: 39189328 PMCID: PMC11443594 SCOPUS ID: 2-s2.0-85202574494 08/27/2024
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(Huang D, Norat P, Qi L, Chernatynskaya A, Cole JD, Mani VJ, Xu L, Liu X, Yang H.) Adv Sci (Weinh). 2024 Aug;11(31):e2401648 PMID: 38874068 PMCID: PMC11336906 SCOPUS ID: 2-s2.0-85195867871 06/14/2024
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(Xu L, Ma X, Yang J, Burken JG, Nam P, Shi H, Yang H.) J Agric Food Chem. 2024 May 15;72(19):11251-11258 PMID: 38699857 SCOPUS ID: 2-s2.0-85192262837 05/03/2024
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(Wang J, Li B, Cooper RC, Huang D, Yang H.) Biomacromolecules. 2024 May 13;25(5):2770-2779 PMID: 38687975 PMCID: PMC11143945 SCOPUS ID: 2-s2.0-85192159789 04/30/2024
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Liposomes-Encapsulating Double-Stranded Nucleic Acid (Poly I:C) for Head and Neck Cancer Treatment.
(Singh V, Chernatynskaya A, Qi L, Chuang HY, Cole T, Jeyalatha VM, Bhargava L, Yeudall WA, Farkas L, Yang H.) ACS Pharmacol Transl Sci. 2024 May 10;7(5):1612-1623 PMID: 38751634 PMCID: PMC11092114 SCOPUS ID: 2-s2.0-85190870664 05/16/2024
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Molecular imaging nanoprobes and their applications in atherosclerosis diagnosis.
(Kou H, Yang H.) Theranostics. 2024;14(12):4747-4772 PMID: 39239513 PMCID: PMC11373619 SCOPUS ID: 2-s2.0-85201469163 09/06/2024
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(Yesbeck N, Huang D, Carrico C, Madurantakam P, Yang H.) Gels. September 2024;10(9) SCOPUS ID: 2-s2.0-85205302174 09/01/2024
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RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension
(Bryce Piper, Srimathi Bogamuwa, Tanvir Hossain, Daniela Farkas, Lorena Rosas, Adam Green, Geoffrey Newcomb, Nuo Sun, Jeffrey C. Horowitz, Aneel R Bhagwani, Hu Yang, Tatiana Kudryashova, Mauricio Rojas, Ana L. Mora, Pearlly Yan, Rama K. Mallampalli, Elena A. Goncharova, David M. Eckmann, Laszlo Farkas.) Journal of Clinical Investigation. 02/01/2024