L. Tugan Muftuler, PhD

Professor

Locations

Neurosurgery
8701 Watertown Plank Rd.
Milwaukee, WI 53226

Education

Postdoctoral Fellow, Radiological Sciences, University of California, Irvine, CA, 1997-1998
PhD, Electrical Electronics Engineering, Technical University, Ankara, Turkey, 1996
MSc, Electrical Electronics Engineering, Orta Dogu Technical University, Ankara, Turkey, 1990
BSc, Electrical Electronics Engineering (Specialized on RF and Microwave eng.), Orta Dogu Technical University, Ankara, Turkey, 1987

Biography

Dr. Muftuler’s primary research interest is to develop novel MRI acquisition, processing and analysis techniques to detect pathophysiological changes caused by various diseases. The technologies that are established in Dr. Muftuler’s lab have been used in neuroimaging, musculoskeletal imaging and cancer imaging studies.

Our objective is to establish a strong research program in MRI technology and build productive collaborations with researchers from diverse backgrounds, which is essential to address increasingly complex clinical problems.

Honors and Awards

03/1989 – 06/1989 UNESCO Fellowship for graduate research in MRI (competitive), Korean Advanced Institute of Science and Technology
08/1992 – 10/1996 Scholarships , Scientific and Technical Research Council of Turkey
03/1997 – 09/1997 NATO B-1 Fellowship for post-doctoral research in the USA, Awarded by NATO, selected by Scientific and Technical Research Council of Turkey (competitive)
2006 – First place award in Engineering Category (competitive): “Head RF Coil Design with Surface Current Density Optimization for SENSE Imaging”, International Society in Magnetic Resonance in Medicine
05/13/2014 – First place award in musculoskeletal MRI research (competitive), International Society of Magnetic Resonance in Medicine
2015/2016 – Changes in perfusion and duffusion in the endplate regions of degenerating intervertebral discs: a DCE-MRI study (Eur Spine J (2015) 24:2458-2467) has been selected as the best basic science paper in the European Spine Journal in the past year for the GRAMMER European Spine Journal Award 2015/2016.

                
                    Research Experience
                
                    Diffusion Magnetic Resonance Imaging
Echo-Planar Imaging
Intervertebral Disc
Magnetic Resonance Imaging
Spine

                    Methodologies and Techniques
                
                    Image Processing, Computer-Assisted

                    Leadership Positions
                
                    Director of MR engineering and MREIT division, University of California, Irvine

                    Educational Expertise
                
                    Electronics
Electronics, Medical
Magnetic Resonance Imaging

Research Interests

Primary research areas

Fast imaging techniques using non-Cartesian sampling methods
Quantitative MRI to study intervertebral disc degeneration
Advanced diffusion MRI techniques applied to concussion and aging studies

Current research

Neuroimaging
Quantitative MRI of the spine
Pulse sequence and RF coil developments
MR based Electrical Impedance Tomography

Associations of prior concussion severity with brain microstructure using mean apparent propagator magnetic resonance imaging.

(Goeckner BD, Brett BL, Mayer AR, España LY, Banerjee A, Muftuler LT, Meier TB.) Hum Brain Mapp. 2024 Jan;45(1):e26556 PMID: 38158641 PMCID: PMC10789198 SCOPUS ID: 2-s2.0-85180852832 01/02/2024
The effects of cytomegalovirus on brain structure following sport-related concussion.

(Savitz J, Goeckner BD, Ford BN, Kent Teague T, Zheng H, Harezlak J, Mannix R, Tugan Muftuler L, Brett BL, McCrea MA, Meier TB.) Brain. 2023 Oct 03;146(10):4262-4273 PMID: 37070698 PMCID: PMC10545519 SCOPUS ID: 2-s2.0-85158119562 04/19/2023
Characterization of diffusion MRI using the mean apparent propagator model in hemodialysis patients: A pilot study.

(Richerson WT, Muftuler LT, Wolfgram DF, Schmit BD.) Magn Reson Imaging. 2023 Oct;102:69-78 PMID: 37150269 PMCID: PMC10524280 SCOPUS ID: 2-s2.0-85158005091 05/08/2023
Diffusion propagator metrics are biased when simultaneous multi-slice acceleration is used.

(Muftuler LT, Nencka AS, Koch KM.) Magn Reson Imaging. 2022 Feb;86:46-54 PMID: 34801673 SCOPUS ID: 2-s2.0-85119508656 11/22/2021
Dynamic tracking of scaphoid, lunate, and capitate carpal bones using four-dimensional MRI.

(Zarenia M, Arpinar VE, Nencka AS, Muftuler LT, Koch KM.) PLoS One. 2022;17(6):e0269336 PMID: 35653348 PMCID: PMC9162359 SCOPUS ID: 2-s2.0-85131243073 06/03/2022
Split-slice training and hyperparameter tuning of RAKI networks for simultaneous multi-slice reconstruction.

(Nencka AS, Arpinar VE, Bhave S, Yang B, Banerjee S, McCrea M, Mickevicius NJ, Muftuler LT, Koch KM.) Magn Reson Med. 2021 Jun;85(6):3272-3280 PMID: 33331002 SCOPUS ID: 2-s2.0-85097598109 12/18/2020
Association of Head Impact Exposure with White Matter Macrostructure and Microstructure Metrics.

(Brett BL, Koch KM, Muftuler LT, Budde M, McCrea MA, Meier TB.) J Neurotrauma. 2021 Feb 15;38(4):474-484 PMID: 33003979 PMCID: PMC7875606 SCOPUS ID: 2-s2.0-85100539318 10/03/2020
Value CMR: Towards a Comprehensive, Rapid, Cost-Effective Cardiovascular Magnetic Resonance Imaging.

(Ibrahim EH, Frank L, Baruah D, Arpinar VE, Nencka AS, Koch KM, Muftuler LT, Unal O, Stojanovska J, Rubenstein JC, Brown SA, Charlson J, Gore EM, Bergom C.) Int J Biomed Imaging. 2021;2021:8851958 PMID: 34054936 PMCID: PMC8147553 SCOPUS ID: 2-s2.0-85107219799 06/01/2021
Optimization of hyperparameters for SMS reconstruction.

(Muftuler LT, Arpinar VE, Koch K, Bhave S, Yang B, Kaushik S, Banerjee S, Nencka A.) Magn Reson Imaging. 2020 Nov;73:91-103 PMID: 32835848 SCOPUS ID: 2-s2.0-85089907300 08/25/2020
Cardiac functional magnetic resonance imaging at 7T: Image quality optimization and ultra-high field capabilities.

(Ibrahim EH, Arpinar VE, Muftuler LT, Stojanovska J, Nencka AS, Koch KM.) World J Radiol. 2020 Oct 28;12(10):231-246 PMID: 33240463 PMCID: PMC7653183 11/27/2020
Serial Diffusion Kurtosis Magnetic Resonance Imaging Study during Acute, Subacute, and Recovery Periods after Sport-Related Concussion.

(Muftuler LT, Meier TB, Keith M, Budde MD, Huber DL, McCrea MA.) J Neurotrauma. 2020 Oct 01;37(19):2081-2092 PMID: 32253977 PMCID: PMC8024361 SCOPUS ID: 2-s2.0-85092679959 04/08/2020
A high-resolution fMRI investigation of BNST and centromedial amygdala activity as a function of affective stimulus predictability, anticipation, and duration.

(Pedersen WS, Muftuler LT, Larson CL.) Soc Cogn Affect Neurosci. 2019 Nov 01;14(11):1167-1177 PMID: 31820811 PMCID: PMC7057282 SCOPUS ID: 2-s2.0-85081945230 12/11/2019

L. Tugan Muftuler, PhD

Professor

Locations

Education

Biography

Honors and Awards

Research Experience

Methodologies and Techniques

Leadership Positions

Educational Expertise

Research Interests

Publications