L. Tugan Muftuler, PhD
Professor
Locations
- Neurosurgery
8701 Watertown Plank Rd.
Milwaukee, WI 53226
Education
PhD, Electrical Electronics Engineering, Technical University, Ankara, Turkey, 1996
MSc, Electrical Electronics Engineering, Orta Dogu Technical University, Ankara, Turkey, 1990
BSc, Electrical Electronics Engineering (Specialized on RF and Microwave eng.), Orta Dogu Technical University, Ankara, Turkey, 1987
Biography
Dr. Muftuler’s primary research interest is to develop novel MRI acquisition, processing and analysis techniques to detect pathophysiological changes caused by various diseases. The technologies that are established in Dr. Muftuler’s lab have been used in neuroimaging, musculoskeletal imaging and cancer imaging studies.
Our objective is to establish a strong research program in MRI technology and build productive collaborations with researchers from diverse backgrounds, which is essential to address increasingly complex clinical problems.
Honors and Awards
08/1992 – 10/1996 Scholarships , Scientific and Technical Research Council of Turkey
03/1997 – 09/1997 NATO B-1 Fellowship for post-doctoral research in the USA, Awarded by NATO, selected by Scientific and Technical Research Council of Turkey (competitive)
2006 – First place award in Engineering Category (competitive): “Head RF Coil Design with Surface Current Density Optimization for SENSE Imaging”, International Society in Magnetic Resonance in Medicine
05/13/2014 – First place award in musculoskeletal MRI research (competitive), International Society of Magnetic Resonance in Medicine
2015/2016 – Changes in perfusion and duffusion in the endplate regions of degenerating intervertebral discs: a DCE-MRI study (Eur Spine J (2015) 24:2458-2467) has been selected as the best basic science paper in the European Spine Journal in the past year for the GRAMMER European Spine Journal Award 2015/2016.
Research Areas of Interest
- Algorithms
- Brain
- Brain Concussion
- Brain Mapping
- Computer Simulation
- Diagnostic Imaging
- Diffusion Magnetic Resonance Imaging
- Diffusion Tensor Imaging
- Electric Conductivity
- Electric Impedance
- Electromagnetic Fields
- Fourier Analysis
Research Experience
- Diagnostic Imaging
- Diffusion Magnetic Resonance Imaging
- Diffusion Tensor Imaging
- Echo-Planar Imaging
- Electric Conductivity
- Electric Impedance
- Electromagnetic Fields
- Fourier Analysis
- Image Enhancement
- Image Interpretation, Computer-Assisted
- Image Processing, Computer-Assisted
- Intervertebral Disc
Methodologies and Techniques
- Image Processing, Computer-Assisted
- Machine Learning
- Supervised Machine Learning
Leadership Positions
- Director of MR engineering and MREIT division, University of California, Irvine
- Faculty IT committee chair. July 2025 - present, MCW
Educational Expertise
- Electronics
- Electronics, Medical
- Magnetic Resonance Imaging
Research Interests
Primary research areas
- Fast imaging techniques using non-Cartesian sampling methods
- Quantitative MRI to study intervertebral disc degeneration
- Advanced diffusion MRI techniques applied to concussion and aging studies
Current research
- Neuroimaging
- Quantitative MRI of the spine
- Pulse sequence and RF coil developments
- MR based Electrical Impedance Tomography
Publications
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(Meier TB, Muftuler LT, Goeckner BD, Weyenberg N, Huber DL, España LY, Banerjee A, Mayer AR, Brett BL.) Hum Brain Mapp. 2025 Nov;46(16):e70392 PMID: 41147238 PMCID: PMC12559924 SCOPUS ID: 2-s2.0-105020246130 10/28/2025
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Abnormal Pattern of Spondylosis and Postflight Neck Flexibility in Fifth-Generation Fighter Pilots.
(Stemper BD, Muftuler LT, Cutlan R, Strother C, Sherman KA, Meier TB, Raff H, Yoganandan N, Gerds B, Dooley C, Le P, Hainsworth KR, Vedantam A.) Aerosp Med Hum Perform. 2025 Oct;96(10):884-893 PMID: 41043817 SCOPUS ID: 2-s2.0-105017693987 10/04/2025
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(Meier TB, Savitz J, España LY, Goeckner BD, Kent Teague T, van der Horn HJ, Tugan Muftuler L, Mayer AR, Brett BL.) Brain Behav Immun. 2025 Jan;123:619-630 PMID: 39414174 PMCID: PMC11624060 SCOPUS ID: 2-s2.0-85206259718 10/17/2024
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Interhemispheric Connectivity of the Human Temporal Lobes.
(Binder JR, Giraldo-Chica M, Mathis J, Tong JQ, Schoenrock S, Arpinar V, Heffernan J, Muftuler LT.) bioRxiv. 2024 Jul 01 PMID: 39005307 PMCID: PMC11244975 07/15/2024
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(Goeckner BD, Brett BL, Mayer AR, España LY, Banerjee A, Muftuler LT, Meier TB.) Hum Brain Mapp. 2024 Jan;45(1):e26556 PMID: 38158641 PMCID: PMC10789198 SCOPUS ID: 2-s2.0-85180852832 01/02/2024
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(Stemper BD, Cutlan R, Vedantam A, Gerds B, Hainsworth K, Raff H, Yoganandan N, Dooley C, Le P, Muftuler LT.) Conference Proceedings International Research Council on the Biomechanics of Injury Ircobi. 2024;Part 202371:353-354 SCOPUS ID: 2-s2.0-85204454527 01/01/2024
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The effects of cytomegalovirus on brain structure following sport-related concussion.
(Savitz J, Goeckner BD, Ford BN, Kent Teague T, Zheng H, Harezlak J, Mannix R, Tugan Muftuler L, Brett BL, McCrea MA, Meier TB.) Brain. 2023 Oct 03;146(10):4262-4273 PMID: 37070698 PMCID: PMC10545519 SCOPUS ID: 2-s2.0-85158119562 04/19/2023
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(Richerson WT, Muftuler LT, Wolfgram DF, Schmit BD.) Magn Reson Imaging. 2023 Oct;102:69-78 PMID: 37150269 PMCID: PMC10524280 SCOPUS ID: 2-s2.0-85158005091 05/08/2023
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Diffusion propagator metrics are biased when simultaneous multi-slice acceleration is used.
(Muftuler LT, Nencka AS, Koch KM.) Magn Reson Imaging. 2022 Feb;86:46-54 PMID: 34801673 SCOPUS ID: 2-s2.0-85119508656 11/22/2021
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Dynamic tracking of scaphoid, lunate, and capitate carpal bones using four-dimensional MRI.
(Zarenia M, Arpinar VE, Nencka AS, Muftuler LT, Koch KM.) PLoS One. 2022;17(6):e0269336 PMID: 35653348 PMCID: PMC9162359 SCOPUS ID: 2-s2.0-85131243073 06/03/2022
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Value CMR: Towards a Comprehensive, Rapid, Cost-Effective Cardiovascular Magnetic Resonance Imaging.
(Ibrahim EH, Frank L, Baruah D, Arpinar VE, Nencka AS, Koch KM, Muftuler LT, Unal O, Stojanovska J, Rubenstein JC, Brown SA, Charlson J, Gore EM, Bergom C.) Int J Biomed Imaging. 2021;2021:8851958 PMID: 34054936 PMCID: PMC8147553 SCOPUS ID: 2-s2.0-85107219799 06/01/2021
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Investigating longitudinal changes in lumbar discs in a two-year interval using quantitative MRI
(L. Tugan Muftuler, Brendan P. Bych, Jordan A. Gliedt, Jeffrey A. King, John P. Wanner, Megan M. Bellman, Pranjal Srivastava.) MedRxiv. doi: https://doi.org/10.1101/2025.05.05.25326903 05/06/2025