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Pharmacology and Toxicology

Auchampach Lab

John A. Auchampach, PhD

johnauchampach
Principal Investigator; Professor, Pharmacology and Toxicology
jauchamp@mcw.edu

Dr. Auchampach is a professor of pharmacology and toxicology and leads an NIH-funded laboratory focused on ischemic heart disease, cardiac regeneration, and drug development.

Our laboratory studies adenosine signaling via its four G protein-coupled receptors during cardiovascular disease. We utilize mice and rats as our model system. I am involved in generating and characterizing new genetic mouse models with global and tissue-specific deletion of specific adenosine receptor subtypes. Other important aspects of my research involve assessing cardiac function (pressure-volume analyses; echocardiography) and conducting surgeries to induce myocardial infarction in rodents. Our laboratory has recently formed a new collaboration with Dr. John Lough in the Department of Cell Biology. The goal of this project using novel genetic mouse models is to test the hypothesis that inhibition of the acetyl transferase Tip60 during myocardial infarction will promote more efficient regeneration by permitting surviving cardiomyocytes to re-enter the cell cycle.

Tina Wan


Tina Wan, PhD
Research Scientist
twan@mcw.edu

 

 

Recent Publications

Publications of John A. Auchampach PhD from the Faculty Collaboration Database

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