- Brian Smith, PhD, Biochemistry
- Medical Scientist Training Program
Cancer Biology, Immunology, Biochemistry
Medical College of Wisconsin, 2021-present
Advisor: Brian Smith, PhD
Project: Polybromo-1 (PBRM1) bromodomain missense mutations in clear cell renal cell carcinoma (ccRCC) vascular signaling pathways
The Catholic University of America, January 2017- May 2019
Advisor: Byung Min (Justin) Chung, PhD
Project: Elucidating the role of Keratin 19 (K19) in the proliferation and migration of MCF7 breast cancer cells.
MD Anderson Cancer Center, June 2018-August 2018
Advisor: Powel Brown, MD, PhD
Project: Determining the effect of the rexinoid IRX 4204 on the proliferation of a panel of breast cancer cell lines.
University of Minnesota, June 2017-August 2017
Advisor: Gregory Vercellotti, MD, FACP
Project: Characterizing the heme binding site on the MD-2/TLR4 transmembrane protein complex.
Khan M, Roddy JT, Hernandez JR, Bursch K, et al. Revisiting biochemistry: severe euglycemic ketoacidosis in the setting of IDH-inhibitor therapy for AML. Br J Haematol. 2021 Jun 7. doi: 10.1111/bjh.17576. Epub ahead of print. PMID: 34101165.
Alsharif S, Sharma P, Bursch K, et al. Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells. Cell Adh Migr. 2021 Dec;15(1):1-17. doi: 10.1080/19336918.2020.1868694. PMID: 33393839; PMCID: PMC7801129.
Sharma P, Alsharif S, Bursch K, Parvathaneni S, Anastasakis DG, Chahine J, Fallatah A, Nicolas K, Sharma S, Hafner M, Kallakury B & Chung BM. Keratin 19 regulates cell cycle pathway and sensitivity of breast cancer cells to CDK inhibitors. Scientific Reports 9, 14650 (2019).
Playing cello and piano, traveling, running, and baking