header-logo
MSTP students in the Sahoo lab
Medical Scientist Training Program
Matthew Brown

Matthew Brown

G2 Student

Faculty Advisor

  • Vera Tarakanova, PhD, Microbiology & Immunology

Locations

  • Medical Scientist Training Program

Contact Information

Education

BA, Biochemistry, University of Colorado Boulder, 2020

Research Interests

Infectious Diseases, Virology, and Immunology

Research Experience

Medical College of Wisconsin, 2024-Present
Advisor: Vera Tarakanova, PhD

HIV Dynamics and Replication Program, National Cancer Institute, 2021- 2022
Advisor: Wei-Shau Hu, PhD
Projects: 1) Using HIV-1 frameshifting to improve methods to study HIV-1 genome packaging and particle formation, 2) Developing a platform for high-throughput screening of compounds antagonistic to coronavirus proteases

University of Colorado Boulder, 2018-2020
Advisor: Marcelo Sousa, PhD
Project: Determining dynamics of the BamA beta-barrel seam in Gram-negative bacteria 

Publications

Schmalzriedt DL, Aurubin CA, Rahlf CR, Brown MA, Bobek JM, Lange PT, Bradeen XG, Sahoo D, Tarakanova VL. Apolipoprotein E selectively supports gammaherpesvirus replication in macrophages. J Virol. 2025 Jun 17;99(6):e0048025. doi: 10.1128/jvi.00480-25. Epub 2025 May 29. PMID: 40439406; PMCID: PMC12172433.

Rawson JMO, Nikolaitchik OA, Yoo JA, Somoulay X, Brown MA, Mbuntcha Bogni FS, Pathak VK, Soheilian F, Slack RL, Sarafianos SG, Hu WS. Adaptation of HIV-1/HIV-2 Chimeras with Defects in Genome Packaging and Viral Replication. mBio. 2022 Oct 26;13(5):e0222022. doi: 10.1128/mbio.02220-22. Epub 2022 Aug 29. PMID: 36036631; PMCID: PMC9600866.

Duchon A, Santos S, Chen J, Brown M, Nikolaitchik OA, Tai S, Chao JA, Freed EO, Pathak VK, Hu WS. Plasma Membrane Anchoring and Gag:Gag Multimerization on Viral RNA Are Critical Properties of HIV-1 Gag Required To Mediate Efficient Genome Packaging. mBio. 2021 Dec 21;12(6):e0325421. doi: 10.1128/mbio.03254-21. Epub 2021 Dec 7. PMID: 34872357; PMCID: PMC8649766.

Meeting Abstracts

Brown MA, Johansen ER, Rahlf CR, Schmalzriedt DL, Tarakanova VL. Host genetic background defines the host and viral parameters of neonatal gammaherpesvirus infection. International Herpesvirus Workshop. Berlin, Germany. July 2025. [Oral and Poster]

Brown MA. Development of a system to simultaneously express two forms of Gag using HIV-1 frameshifting. Presented at National Cancer Institute's Center for Cancer Research Fellows and Young Investigators Seminar Series, Virtual, February 2022.

Brown MA, Doerner PA, and Sousa MC. A Comparison of in vivo and in vitro BamA Barrel Seam Dynamics. Presented at Biophysical Society Annual Meeting, San Diego, CA, February 2020. 

General Interests

I enjoy activities outdoors like skiing, hiking, and camping. During my MD/PhD training I have been enjoyed learning to play golf. I also enjoy reading good books and playing chess.

© 2025 Medical College of Wisconsin.  All rights reserved.  | Terms and Privacy | Web Accessibility Statement

Non-Discrimination, Anti-Harassment, and Legal Compliance Statement
The Medical College of Wisconsin (MCW) is committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, military status, or other legally protected classification. MCW maintains full compliance with all applicable federal, state, and local laws and regulations in pursuit of our missions. Consistent with federal guidance, we affirm our commitment to individual merit, fairness, and equal treatment in all aspects of academic and institutional decision-making.

MCW's policies, federal and state laws, and regulations prohibit unlawful discrimination and harassment. Employees, learners, students, applicants, or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.