Research Collaborate Lab Bench

Medical Scientist Training Program

Moujtaba Kasmani

Moujtaba Kasmani

G3 Student

Faculty Advisor

  • Weiguo Cui, PhD, Microbiology & Immunology

Locations

  • Medical Scientist Training Program

Contact Information

Education

BS, Biochemistry and Mathematics, University of Tulsa, 2016

Research Interests

CD8 T cell exhaustion, bioinformatics

Research Experience

Medical College of Wisconsin, 2019-present
Advisor: Weiguo Cui, PhD
Project: Mechanistic study of TCR signaling strength in CD8 T cell differentiation during pathogenesis of T1DM (F30DK127526) 

The University of Tulsa, 2014-2016
Advisor: Akhtar Ali, PhD
Project: Sequencing and phylogenetic analysis of Wheat streak mosaic virus isolates

The University of Tulsa, 2012-2014
Advisor: Justin Chalker, DPhil
Project: Synthesis of a sulfur-free IPTG mimic to induce gene expression under oxidative stress

Publications

Kasmani MY, Cui W. Inhibiting BRD4 to generate BETter T cell memory. J Exp Med. 2021 Jun 16;218:8–10. doi: 10.1084/jem.20210877

Chen Y, Zander R, Wu X, Schauder DM, Kasmani MY, et al. BATF regulates progenitor to cytolytic effector CD8+ T cell transition during chronic viral infection. Nat. Immunol. Accepted.

Stancill JS, Kasmani MY, Khatun A, Cui W, Corbett JA. Single-cell RNA sequencing of mouse islets exposed to proinflammatory cytokines. Life Sci Alliance. 2021 Jun;4(6). doi: 10.26508/lsa.202000949. Print 2021 Jun. PubMed PMID: 33883217; PubMed Central PMCID: PMC8091599.

Volberding PJ, Xin G, Kasmani MY, et al. Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection. Cell Rep. 2021 May 25;35(8):109160. doi: 10.1016/j.celrep.2021.109160. PubMed PMID: 34038722; PubMed Central PMCID: PMC8182757.

Schauder DM, Shen J, Chen Y, Kasmani MY, Kudek MR, Burns R, Cui W. E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16). doi: 10.1073/pnas.2013452118. PubMed PMID: 33859041; PubMed Central PMCID: PMC8072256.

Xin G, Chen Y, Topchyan P, Kasmani MY, et al. Targeting PIM1-Mediated Metabolism in Myeloid Suppressor Cells to Treat Cancer. Cancer Immunol Res. 2021 Apr;9(4):454-469. doi: 10.1158/2326-6066.CIR-20-0433. Epub 2021 Feb 12. PubMed PMID: 33579728; PubMed Central PMCID: PMC8137571.

Topchyan P, Xin G, Chen Y, Zheng S, Burns R, Shen J, Kasmani MY, et al. Harnessing the IL-21-BATF Pathway in the CD8+ T Cell Anti-Tumor Response. Cancers (Basel). 2021 Mar 12;13(6). doi: 10.3390/cancers13061263. PubMed PMID: 33809259; PubMed Central PMCID: PMC7998696.

Khatun A, Kasmani MY, Zander R, Schauder DM, et al. Single-cell lineage mapping of a diverse virus-specific naive CD4 T cell repertoire. J Exp Med. 2021 Mar 1;218(3). doi: 10.1084/jem.20200650. PubMed PMID: 33201171; PubMed Central PMCID: PMC7676493.

Moorman, R. M.; Kasmani, M. Y.; Peeples, C. J.; Chalker, J. M. (2015). Inquiry-Driven Investigation of the Copper-Catalyzed Azide-Alkyne Cycloaddition in the Undergraduate Organic Chemistry Laboratory. Chem. Educator, 20, 214-219.

Meeting Abstracts

Kasmani MY, Ali, A. Detection of Wheat streak mosaic virus in Oklahoma. University of Tulsa/University of Oklahoma Research Colloquium. Tulsa, OK. 2016.

Kasmani MY, Schmauch MM, Bardeaux MC, Chalker JM. Investigation of recombinant protein expression under oxidative conditions. American Chemical Society. Dallas, TX. 2014.

General Interests

Reading, tea, coffee, hiking, tennis