Medical Scientist Training Program
Medical Scientist Training Program
SaiSuma Samudrala

Suma Thareja

Postdoctoral Fellow

Faculty Advisor

  • Aoy Mitchell, PhD, Cell Biology, Neurobiology & Anatomy

Locations

  • Medical Scientist Training Program
    Kern Scholars Program
    All of Us Wisconsin

Contact Information

Education

BS, Molecular Biology, University of Wisconsin-Madison, 2016

Research Interests

Translating genetic research into cardiac clinical understanding and care. Training at the intersection of medical education and community engagement. Interested in promoting whole health, ensuring health equity, and addressing food insecurity. I am passionate about building pipeline programs for health and science careers.

Research Experience

Medical College of Wisconsin, 2022-Present
Advisor: Jeff Fritz, PhD, MS, MATL
Training Experience: Human-centered design, Quantitative and qualitative research design methods in medical education, Community-driven research

Medical College of Wisconsin, 2018-2022
Advisor: Aoy Mitchell, PhD
Project: Novel KLHL26 variant associated with a familial case of Ebstein’s anomaly and left ventricular non-compaction

University of Wisconsin-Madison, 2013-2015
Advisor: Barry Ganetzky, PhD
Project: A Drosophila genetic screen to find therapeutic targets for radiotherapy, a common treatment for central nervous system malignancies

University of Wisconsin-Madison, 2014-2016
Advisor: Peter Lewis, PhD
Project: Understanding the structural and functional importance of basic patch residues in the highly conserved histone binding domain of the chaperone protein Death-domain associated protein 6 (Daxx)

Publications

Thareja SK, Frommelt MA, Lincoln J, Lough JW, Mitchell ME, Tomita-Mitchell A. A Systematic Review of Ebstein's Anomaly with Left Ventricular Noncompaction. J Cardiovasc Dev Dis. 2022 Apr 13;9(4):115. doi: 10.3390/jcdd9040115. PMID: 35448091; PMCID: PMC9031964.

Kim MS, Fleres B, Lovett J, Anfinson M, Samudrala SSK, et al. Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome. Front Cell Dev Biol. 2020 Jun 23;8:440. doi: 10.3389/fcell.2020.00440. PMID: 32656206; PMCID: PMC7324479.

Samudrala SSK, North LM, Stamm KD, et al. Novel KLHL26 variant associated with a familial case of Ebstein's anomaly and left ventricular noncompaction. Mol Genet Genomic Med. 2020 Apr;8(4):e1152. doi: 10.1002/mgg3.1152. Epub 2020 Jan 27. PMID: 31985165; PMCID: PMC7196453.

Geddes GC, Samudrala SS, Earing MG. Neonatal Assessment of Infants with Heterotaxy. Clin Perinatol. 2020 Mar;47(1):171-182. doi: 10.1016/j.clp.2019.10.011. Epub 2019 Oct 31. PMID: 32000924.

Sudmeier LJ, Samudrala SS, Howard SP, Ganetzky B. Persistent Activation of the Innate Immune Response in Adult Drosophila Following Radiation Exposure During Larval Development. G3 (Bethesda). 2015 Sep 1;5(11):2299-306. doi: 10.1534/g3.115.021782. PMID: 26333838; PMCID: PMC4632050.

Meeting Abstracts

Thareja (Samudrala) S, Anfinson M, Cavanaugh M, Kim M, Lamberton P, Radandt J, Brown R, Liang HL, Stamm K, Afzal Z, Strande J, Frommelt MA, Lough JW, Fitts R, Mitchell M, and Tomita-Mitchell A. Decreased Contraction Rate, Altered Calcium Transients, and Increased Proliferation seen in Patient-Specific iPSC-CMs Modeling Ebstein’s Anomaly and Left Ventricular Noncompaction. Weinstein Cardiovascular Development & Regeneration, Palais du Pharo, Marseilles, France, May 2022.

Thareja (Samudrala) S, Anfinson M, Cavanaugh M, Kim M, Lamberton P, Radandt J, Brown R, Liang HL, Stamm K, Afzal Z, Strande J, Frommelt MA, Lough JW, Fitts R, Mitchell M, and Tomita-Mitchell A. Decreased Contraction Rate, Altered Calcium Transients, and Increased Proliferation seen in Patient-Specific iPSC-CMs Modeling Ebstein’s Anomaly and Left Ventricular Noncompaction. Experimental Biology, Pennsylvania Convention Center, Philadelphia, PA. Apr 2022.

Samudrala SS, North L, Stamm K, Earing M, Frommelt MA, Willes R, Tripathi S, Dsouza N, Zimmermann M, Mahnke D, Liang HL, Lund M, Lin C, Geddes GC, Afzal Z, Strande J, Lough JW, Mitchell M, and Tomita-Mitchell A. Novel KLHL26 variant associated with a familial case of Ebstein’s anomaly and left ventricular non-compaction. Weinstein Cardiovascular Development Conference, May 2019.

Samudrala S, North L, Kim M, Strande Jennifer, Zeeshan A, Frommelt MA, Earing M, Lough JW, Mitchell M, and Tomita-Mitchell A. Patient-specific induced pluripotent stem cells to model Ebstein’s anomaly (EA) with left ventricular non-compaction (LVNC). Midwest Pediatric Cardiology Society, St. Louis, MO, September 2017.

General Interests

Tennis, violin, running, reading, and painting