Wasif Osmani, PhD

Neurophysiology of breathing, Epilepsy

Research Experience

Medical College of Wisconsin, 2019-2023
Advisor: Matthew Hodges, PhD
Project: Investigating the Role of Neuroinflammation in Cognition and Cardiorespiratory Control in a Rodent Model of Recurrent Epilepsy

Loyola University Chicago 2013-2016
Advisor: Jessica Brann, PhD

University of Chicago at Illinois (UIC) 2016
Advisor: Primal de Lanerolle, PhD

National Institutes of Aging (NIA), NIH 2016-2017
Advisor: Dr. Vilhelm Bohr, MD PhD and Mustafa Okur, PhD

Publications

Manis AD, Cook-Snyder DR, Duffy E, Osmani WA, Eilbes M, Dillard M, Palygin O, Staruschenko A, Hodges MR. Repeated seizures lead to progressive ventilatory dysfunction in SSKcnj16-/- rats. J Appl Physiol (1985). 2023 Oct 1;135(4):872-885. doi: 10.1152/japplphysiol.00072.2023. Epub 2023 Aug 3. PMID: 37535709.

Okur MN, Mao B, Kimura R, Haraczy S, Fitzgerald T, Edwards-Hollingsworth K, Tian J, Osmani W, et al. Short-term NAD+ supplementation prevents hearing loss in mouse models of Cockayne syndrome. NPJ Aging Mech Dis. 2020 Jan 7;6:1. doi: 10.1038/s41514-019-0040-z. PMID: 31934345; PMCID: PMC6946667

Okur MN, Lee JH, Osmani W, Kimura R, Demarest TG, Croteau DL, Bohr VA. Cockayne syndrome group A and B proteins function in rRNA transcription through nucleolin regulation. Nucleic Acids Res. 2020 Mar 18;48(5):2473-2485. doi: 10.1093/nar/gkz1242. PMID: 31970402; PMCID: PMC7049711. 

Meeting Abstracts

Osmani W, Duffy E, Manis A, et al. (2021), Single Nuclear RNA Sequencing Reveals Activation of Neuroinflammation Within the Pre-Bötzinger Complex Following Repeated Seizures. The FASEB Journal, 35:. https://doi.org/10.1096/fasebj.2021.35.S1.02780

Osmani W, Duffy E, Manis A, Kasmani, M, Khatun A, Chen Y, Mouradian G, Forster H, Hodges M. Single Nuclear Transcriptomes of Raphe Cell Types May be Altered with Repeated Seizures. Poster presented at: Experimental Biology; 2020 Apr; San Diego, CA

Cory M, Osmani W, Cory K, Lamberton N, Lundh R, Young S. Creating Health Education for Constructive Knowledge in Underserved Populations (CHECK UP) Program. Workshop (90 min) presented at: Society of Teachers of Family Medicine; 2020 Mar; Salt Lake City, UT

Cory M, Osmani W, Cory K, Lamberton N, Lundh R, Young S. Creating Health Education for Constructive Knowledge in Underserved Populations (CHECK UP) Program – Filling the Medical Education Gap. Workshop (60 min) presented at: Society of Student-Run Free Clinics Annual Conference; 2020 Mar; Orlando, FL

Cory M, Osmani W, Cory K, Lamberton N, Lundh R, Young S. Creating Health Education for Constructive Knowledge in Underserved Populations (CHECK UP) Program. Poster presented at: AAMC Annual Meeting 2019; 2019 Nov; Phoenix, AZ

Osmani W, Okur MN, Croteau D, Bohr VA. Convergence of Cockayne Syndrome group A and B Proteins on Nucleolin Regulation. Poster presented at: NIH Postbaccalaureate Poster Day; 2017 May; Bethesda, MD

Osmani W, Brann JH. The Role of OMP in Neuronal Regeneration and Maturation”. Poster presented at: Chicago Area Undergraduate Research Symposium (CAURS); 2016, April 9; Chicago, IL

Osmani W, Brann JH. The Role of Chemokine Receptor 4 in Neural Regeneration. Poster presented at: Chicago Area Undergraduate Research Symposium (CAURS); 2015, April 11; Chicago, IL

General Interests

Reading, writing, eating, living, breathing, musical theater, symphonies, John Williams