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Dr. Mickevicius Publishes Letter to Editor of Magnetic Resonance in Medicine

Dr. Mickevicius Publishes Letter to Editor of Magnetic Resonance in Medicine

December 31, 2025

Nikolai Mickevicius, PhD, assistant professor of biophysics at MCW, published a letter to the editor in Magnetic Resonance in Medicine, titled "Generalized Analytical Non-Balanced SSFP Signal Expressions for Systems With Magnetization Transfer," in December 2025.

Magnetization transfer describes the interaction between hydrogen protons in water molecules and hydrogen protons that are bound to larger molecules. Simulating a biological tissue’s response to the switching magnetic fields of an MRI scanner typically involves very demanding computations when considering magnetization transfer. In this work, new algebraic equations were derived that describe the tissue response to a very specific type of MRI scan – steady-state free precession – without any intense computations. This has implications for studies aiming to quantify the fraction of protons in each MRI pixel that are in large molecules versus free water molecules.

Tagged: Biophysics Research – Basic Sciences

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