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Dr. Subczynski Article Discusses Role of Cholesterol in Cataract Formation

January 5, 2026

A review article published by W. Karol Subczynski, PhD, DSc, and national and international collaborators explores whether cholesterol is the key to preventing the development of age-related cataracts in the eye's central lens.

This article, titled "Preventing Age-Related Nuclear Cataract Development - Is Cholesterol the Key?" was published by Investigative Ophthalmology & Visual Science. It is a review of the existing literature on cholesterol content in the membranes of the fiber cells as a factor that may protect against nuclear cataract formation. The article asserts that understanding why human eye lenses contain high levels of cholesterol is essential to describe its fundamental biology, determine how environmental and genetic factors impact its transparency, and develop treatments for lens opacities. Co-authors include Laxman Mainali (Boise State University), Ross Collery (MCW), Marta Pasenkiewicz-Gierula (Jagiellonian University), and Justyna Widomska (Medical University of Lublin).

Tagged: Biophysics Research – Basic Sciences Ophthalmology

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