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Dr. Jeannette Vasquez Vivar Receives Multi-PI R01 from NINDS

Collaborators Sidhartha Tan, MD, at Wayne State University; Jie Xu at University of Michigan, PhD; and Jeannette Vasquez Vivar, PhD, at the Medical College of Wisconsin were awarded R01NS130258 by the National Institute of Neurological Disorders. The overall goal of this project is to map together possible pathways to establish the most significant mechanisms of oxidant injury to brain loss of function; this will render critical information to define better therapies for fetal brain hypoxia-ischemia injury.

This multiple-PI project is the product of the intersection of collaborators with expertise in neonatology and movement disorders (Dr. Tan); application of  CRISPR-CAS technology in large animal models (Dr. Xu); and tetrahydrobiopterin/nitric oxide synthase, free radicals, and electron paramagnetic resonance (Dr. Vasquez Vivar).