What is the procedure for conducting human subject research using MRI?
The process for conducting human subject research using MRI involves several steps.
How do I obtain permission to use Medical College of Wisconsin MRI Scanners?
You must apply through the Center for Imaging Research to obtain permission.
How do I obtain permission to use MRI scanners at Froedtert, Children's or other affiliated institutions?
You must contact the institution where you are proposing to use the MRI scanner.
FH: Office of Clinical Research and Innovative Care Compliance (OCRICC) (414) 805-4082
CHW: Office of Corporate Compliance Children's Hospital and Health System
(CHHS) Diane Bauer at (414) 266-6237 or firstname.lastname@example.org
What Research MRI Safety Committee approvals do I need?
Research MRI Safety Committee approval is required prior to IRB (human studies) or IACUC (animal studies) approval.
MRI Research Using Human Subjects (DOCX)
MRI Research Using Animals (DOCX)
Assistance is available via MRIresearch@mcw.edu
Approval is also needed from the Center for Imaging Research if the Medical College of Wisconsin scanners are requested.
Can you explain the process for MRI Safety approval?
The Research MRI Safety review and approval process has been charted for your reference.
What can I do to streamline the approval process?
Investigators and study team members working with the Medical College of Wisconsin MRI scanners for research must complete MRI Safety Training.
Applications for research must be submitted to the IRB (Human subjects) or the IACUC (Animal Subjects) and the appropriate MRI Research form completed.
Approval for use of the Medical College of Wisconsin scanners in the FH Pavilion and or the MFRC building is required from the Center for Imaging Research.
Approval for use of Froedtert, Children's or other affiliated MRI scanners must be obtained from those institutions.
Is research monitored following approval?
Research is monitored for safety at each MRI study session using the Medical College of Wisconsin (MCW) scanners, by the MRI Scanner Operators.
The MRI Scanner Operators have the authority to stop a study session if they deem there is a significant safety risk to continue.
Research is additionally monitored as needed by the Research MRI Safety Committee, whose mission is to foster an environment for the safe use of MRI in research at MCW. This includes ensuring properly trained personnel are on site, equipment is being operated safely, and that subjects are adequately screened for safety.
What can I do to prevent problems in the laboratory?
The Research MRI Safety Committee has developed Standard Operating Procedures to guide safe practices for the use of Magnetic Resonance Imaging for research at the Medical College of Wisconsin. It is expected that all investigators and study team personnel adhere to these procedures.
Questions and concerns may be addressed to the Research MRI Safety Committee: MRIresearch@mcw.edu
What training is required?
MRI Safety Training is required for study personnel working in the magnetic environment or recruiting human subjects who will enter the magnetic environment of the scanners at the Medical College of Wisconsin (MCW). Training includes a description of the dangers within the magnetic environment and instructions for identifying subjects and equipment that should not enter the magnetic environment.
Principal Investigators who will conduct research using the MCW scanner(s) are required to complete MRI Safety Training as they are ultimately responsible for the safety of the study. Training may be modified depending on the previous MRI experience of the investigator.
What resources are available?
What are the relevant policies, procedures and guidelines?
Please review the Standard Operating Procedures (SOPs) within the Research MRI Safety Committee website prior to conducting research using MRI at the Medical College of Wisconsin.
Whom do I contact if I have additional questions?
Research MRI Safety Committee
General Inquiries: MRIresearch@mcw.edu
Chair: Andrew Nencka, PhD email@example.com
Safety Training: Steve Jankowski, BS RT (R)(MR) firstname.lastname@example.org
Office of Research
General Inquiries: email@example.com
Center for Imaging Research
Debra Keiler firstname.lastname@example.org
(414) 955-6562 (fax)