
Caitlin O'Meara, PhD
Assistant Professor
Locations
- Cardiovascular Center
Contact Information
Education
Postdoctoral Training, Harvard Medical School, 2016
Research Interests
Publications
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Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes.
(Flinn MA, Otten C, Brandt ZJ, Bostrom JR, Kenarsary A, Wan TC, Auchampach JA, Abdelilah-Seyfried S, O'Meara CC, Link BA.) Development. 2020 Aug 25;147(16) PMID: 32843528 PMCID: PMC7473637 SCOPUS ID: 2-s2.0-85089923843 08/28/2020
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Upstream regulation of the Hippo-Yap pathway in cardiomyocyte regeneration.
(Flinn MA, Link BA, O'Meara CC.) Semin Cell Dev Biol. 2020 04;100:11-19 PMID: 31606277 PMCID: PMC7263368 SCOPUS ID: 2-s2.0-85073003673 10/14/2019
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Steps toward therapeutically targeting the activin type II receptor for treating heart failure.
(Paddock SJ, O'Meara CC.) Am J Physiol Heart Circ Physiol. 2020 02 01;318(2):H326-H328 PMID: 31922889 PMCID: PMC7052619 01/11/2020
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(Flinn MA, Jeffery BE, O'Meara CC, Link BA.) Cardiovasc Res. 2019 03 01;115(3):570-577 PMID: 30295714 SCOPUS ID: 2-s2.0-85061983162 10/09/2018
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IL-13 promotes in vivo neonatal cardiomyocyte cell cycle activity and heart regeneration.
(Wodsedalek DJ, Paddock SJ, Wan TC, Auchampach JA, Kenarsary A, Tsaih SW, Flister MJ, O'Meara CC.) Am J Physiol Heart Circ Physiol. 2019 01 01;316(1):H24-H34 PMID: 30339498 SCOPUS ID: 2-s2.0-85060194313 10/20/2018
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Soluble interleukin-13rα1: a circulating regulator of glucose.
(Rachmin I, O'Meara CC, Ricci-Blair EM, Feng Y, Christensen EM, Duffy JF, Zitting KM, Czeisler CA, Pancoast JR, Cannon CP, O'Donoghue ML, Morrow DA, Lee RT.) Am J Physiol Endocrinol Metab. 2017 12 01;313(6):E663-E671 PMID: 28874358 PMCID: PMC5814599 09/07/2017
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Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration.
(Mahmoud AI, O'Meara CC, Gemberling M, Zhao L, Bryant DM, Zheng R, Gannon JB, Cai L, Choi WY, Egnaczyk GF, Burns CE, Burns CG, MacRae CA, Poss KD, Lee RT.) Dev Cell. 2015 Aug 24;34(4):387-99 PMID: 26256209 PMCID: PMC4550513 08/11/2015
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Peering Into the Cardiomyocyte Nuclear Epigenetic State.
(O'Meara CC, Lee RT.) Circ Res. 2015 Aug 14;117(5):392-4 PMID: 26271534 PMCID: PMC4538702 08/15/2015
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Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis.
(Jiang J, Burgon PG, Wakimoto H, Onoue K, Gorham JM, O'Meara CC, Fomovsky G, McConnell BK, Lee RT, Seidman JG, Seidman CE.) Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9046-51 PMID: 26153423 PMCID: PMC4517252 07/15/2015
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(Bryant DM, O'Meara CC, Ho NN, Gannon J, Cai L, Lee RT.) J Mol Cell Cardiol. 2015 May;82:184-5 PMID: 25771145 03/17/2015
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SH2B3 Is a Genetic Determinant of Cardiac Inflammation and Fibrosis.
(Flister MJ, Hoffman MJ, Lemke A, Prisco SZ, Rudemiller N, O'Meara CC, Tsaih SW, Moreno C, Geurts AM, Lazar J, Adhikari N, Hall JL, Jacob HJ.) Circ Cardiovasc Genet. 2015 Apr;8(2):294-304 PMID: 25628389 SCOPUS ID: 2-s2.0-84942919523 01/30/2015
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A systematic analysis of neonatal mouse heart regeneration after apical resection.
(Bryant DM, O'Meara CC, Ho NN, Gannon J, Cai L, Lee RT.) J Mol Cell Cardiol. 2015 Feb;79:315-8 PMID: 25533939 PMCID: PMC4302033 12/24/2014
O'Meara Lab Staff

Samantha Paddock
Graduate Student
I'm interested in how the IL13 signaling axis, specifically IL4Ra, signals to cardiomyocytes to promote cardiac regeneration. Additionally, I'm pursuing how IL13 signaling can promote cardiomyocyte cell cycle activity and cardioprotection after the neonatal regenerative window has closed.

Santiago Alvarez, MD
Graduate Student
My research interest focuses on cardiac recovering, tissue remodeling and heart failure development after acute cardiac injury, looking particularly at the role of interleukin 4 and 13 in cardiac macrophages in promoting cardiac regeneration and improving outcome.

Michael Flinn, PhD
Appointment Years: 2020-2021 | Current Position: Postdoctoral Fellow
Current Institution: Medical College of Wisconsin

Victor Alencar
Research Technician
My research interests span throughout various fields of biology, but specially in physiology of cardiac regeneration. I am thrilled to collaborate with the lab team and their research projects, taking joy in learning new techniques to move our lab discoveries forward.

Jerrell Lovett
Graduate Student
I have a passion for studying integrative physiology, muscle physiology, immunology, and various pathologies.