Staff Collaborate Conference Room

Caitlin O'Meara, PhD

Caitlin O'Meara, PhD

Caitlin O'Meara, PhD

Assistant Professor

Locations

  • Cardiovascular Center

Contact Information

Education

PhD, Medical College of Wisconsin, 2011
Postdoctoral Training, Harvard Medical School, 2016

Research Interests

Higher organisms such as zebrafish and neonatal mice are capable of complete heart regeneration following partial amputation. Although adult humans and adult mice lack this regeneration response, there is great interest in understanding how heart regeneration can occur in lower organisms so that we can activate this process in humans to better treat patients following myocardial infarction. My lab is interested in understanding the cell biology and molecular pathways that facilitate heart regeneration and cardiomyocyte cell cycle activity. Factors that we find to mediate cardiac regeneration in zebrafish or neonatal mice are then tested in adult non-regenerative mammalian models to identify potential therapeutic targets for promoting cardiac healing.

Publications

O'Meara Lab Staff

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Samantha Paddock

Graduate Student

spaddock@mcw.edu

I'm interested in how the IL13 signaling axis, specifically IL4Ra, signals to cardiomyocytes to promote cardiac regeneration. Additionally, I'm pursuing how IL13 signaling can promote cardiomyocyte cell cycle activity and cardioprotection after the neonatal regenerative window has closed.

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Santiago Alvarez, MD

Graduate Student

salvarez@mcw.edu

My research interest focuses on cardiac recovering, tissue remodeling and heart failure development after acute cardiac injury, looking particularly at the role of interleukin 4 and 13 in cardiac macrophages in promoting cardiac regeneration and improving outcome.

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Michael Flinn, PhD

Postdoctoral Fellow

mflinn@mcw.edu

My research is focused on addressing the role of Hippo-Yap signaling following ischemic injury in context of heart failure or cardiac regeneration.

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Victor Alencar

Research Technician

valencar@mcw.edu

My research interests span throughout various fields of biology, but specially in physiology of cardiac regeneration. I am thrilled to collaborate with the lab team and their research projects, taking joy in learning new techniques to move our lab discoveries forward.