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Tissue Regenerative Engineering Laboratory

About the Tissue Regenerative Engineering Laboratory

Led by Professor Bo wang, the Tissue Regenerative Engineering Laboratory at the Marquette-MCW Joint Department of Biomedical Engineering works with students and collaborators to investigate the regenerative properties of biomaterials such as placenta and bone matrices.  Their ultimate goal is to develop new therapies for various forms of bone and tissue damage. 
Wang Laboratory-Intro Component
Blood vessel tissue

About TRE Lab Research

The Tissue Regenerative Engineering Laboratory is developing bio-functional engineered tissues that provide advanced therapeutic options for such conditions as birth defects, bone disorders, and liver and vascular diseases. To do this, the TRE Lab will first develop a greater understanding of the biological and molecular processes involved in regenerative regression.

Learn more about TRE Lab Research

Investigators

Principal Investigator  

Dr. Bo Wang

Bo Wang, PhD

Dr. Bo Wang, Director and Principal Investigator of the TRE Lab, received her PhD in Biomedical Engineering from Mississippi State University in 2012 and completed her Postdoctoral Fellowship at Northwestern University's Feinberg School of Medicine, Department of Surgery, in 2016. She joined the Marquette-MCW Joint Department of Biomedical Engineering in January of 2019 with research interests that include stem cell engineering, hard-tissue engineering and 3D bioprinting, as well as vascular tissue engineering, imaging, modeling and simulation.

Learn more about Dr. Wang

Investigative Collaborators

In its efforts to advance knowledge and therapeutic options for individuals suffering from tissue and bone defect and disease, the TRE Lab works closely with investigative collaborators from Children's Wisconsin, Froedtert Hospital and the Medical College of Wisconsin specializing in Nanotechnology and Vascular Surgery.

Learn more about TRE Lab People

In the News

x-ray of finger bones

Regenerating Blood Vessels and Bone with Biomaterials and Nanotechnology 

MCW Knowledge, August 2025

  

Funding

The Tissue Regenerative Engineering Laboratory receives support on an ongoing basis from the Medical College of Wisconsin and on a per-project basis from such institutions as the Advancing a Healthier Wisconsin Endowment (AHW). 
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Ongoing Support
  • 2026-2031 Bone-Derived Nanoparticles for Targeted rhBMP2 Delivery to Restore Function and Promote Osteogenic Differentiation in Radiation-Damaged Bone Marrow Stem Cells, NIH R01, Grant Number: 1R01AR087376-01, Role: PI, $1,996,857.
  • 2026-2027 Bone-Based Nanoparticles, A Biomaterial Based Therapeutic for Craniomaxillofacial Reconstruction, American Association of Plastic Surgeons (AAPS) Academic Scholar Grant, Role: Co-PI (PI: Shakir Shakir), $70,000.
Past Support
  • 2025-2026 Translating Porcine Bone into Image-Guided and Bone-Targeted Nanoparticles, Department Product Development Pilot Award, Role: PI, $50,000.
  • 2024-2025 Nanosized Bone Particles with Decellularized Amniotic Membrane, An Alternative Grafting Biomaterial in Cleft Lip/Palate, MTF Biologics awards, Role: PI, $75,000.
  • 2024-2025: Biofabrication of Small Vascular Graft with Human Amniotic Membrane, Advancing a healthier Wisconsin (AHW) Pilot Award, Role: PI, $50,000.
  • 2024-2025 Enhancing the Clinical Utility of Bone Morphogenetic Protein 2 Using Bone-Based Nanoparticles. Children’s Wisconsin, Children’s Research Institute Pilot Grant, Role: co-PI (PI: Shakir Shakir) $74,693.
  • 2024-2025 Enhancing the Clinical Utility of Bone Morphogenetic Protein 2 Using Bone-Based Nanoparticles. American Society of Maxillofacial Surgeons / Maxillofacial Surgeons Foundation, Role: co-PI (PI: Shakir Shakir) $10,000. 2022-2024 Development of a Compliant and Biomimetic Small Vascular Graft with Human Amnion Membrane, Advancing a healthier Wisconsin (AHW) Research and Education Program, Role: PI, $200,000.
  • 2020-2021 Develop an Individualized Composite as an Interface for Severe Cleft Palate Repair”, Research Affairs Committee (RAC) of Medical College of Wisconsin, Role: PI, $25,000.
  • 2019-2022: Tissue-Engineered Vascular Graft of Small Diameter Using Porcine Artery, Advancing a healthier Wisconsin (AHW) Research and Education Program, Role: PI, $590,528.
  • 2018-2021 Development of an Individualized Multiplex Composite as an Interface for Severe Cleft Palate Repair, NIH R15, Role: PI, $354,805.
  • 2017-2021 Optimization and Enhancement of Hepatic Differentiation for Mesenchymal Stem Cells via Biofunctional Modification, NSF Research Initiation Award, Role: PI, $300,000.
  • 2016-2017 Acquisition of a Multimaterial 3-D Bioplotter for Interdisciplinary Research and Education, NSF MRI, Role: Co-PI (PI: Derrick Dean) $271,535.

Contact Us!

For additional information about the Tissue Regenerative Engineering Laboratory or to learn more about open positions, contact us!

Contact Dr. Bo Wang

bowang@mcw.edu
(414) 955-2346

 

Lab: MCW Campus, TBRC C2788
Office: TBRC C2815

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