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Physical Medicine and Rehabilitation

Research

PMR_ResearchTeamThe PM&R Research Program has been established to advance the science and the practice of physical medicine and rehabilitation by conducting research aimed at studying and reducing impairments and functional disabilities due to disease or traumatic events.

We have several collaborations focused on clinical and translational, and community engaged research. Current research areas include spinal cord injury, physical activity for individuals with disabilities, stroke rehabilitation, spasticity management, pain, and prosthetics. Our collaborators include faculty from Neurosurgery and Neurology at Froedtert Hospital/The Medical College of Wisconsin, Marquette University, UW-Milwaukee, and several community organizations.

Our Residency Program offers a Research Intensive Track with protected research time, funding, and significant mentorship opportunities. Please visit the Residency Program page for more information on resident research.

The Stroke Rehabilitation Center of Southeastern Wisconsin

Our partnership with Marquette University has established The Stroke Rehabilitation Center of Southeastern Wisconsin (SRC). The goal of this center is to conduct cutting edge rehabilitation research to improve functional outcomes for stroke survivors. Our research in this area is guided by a Community Academic Advisory Board comprised of clinicians, stroke survivors, caregivers, and academic researchers.

Research Team (right)

Back row, l-r: Moriah Iverson, Matt Durand
Front row, l-r: Jennifer Nguyen, Rachel Minkin

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Publications

Belanger, HG; Powell-Cope, G; Spehar, AM; McCranie, M; Klanchar, SA; Yoash-Gantz, R; Kosasih, JB; Scholten, J. The Veterans Health Administration's traumatic brain injury screen and evaluation: Practice patterns. J Rehabil Res Dev. 2016;53(6):767-780.

Beyer AM, Freed JK, Durand MJ, Riedel M, Ait-Aissa K, Green P, Hockenberry JC, Morgan RG, Donato AJ, Peleg R, Gasparri M, Rokkas CK, Santos JH, Priel E, Gutterman DD Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation. Circ Res. 2016 Mar 4;118(5):856-66.

Bril, V; England, J; Franklin, GM; Backonja, M; Cohen, J; Del Toro, D; Feldman, E; Iverson, DJ; Perkins, B; Russell, JW; Zochodne, D. Evidence-based guideline: Treatment of painful diabetic neuropathy: Report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation. PM R. 2011 Apr;3(4):345-52, 352.

Buchanan CE1, Kadlec AO, Hoch AZ, Gutterman DD, Durand MJ. Hypertension during Weight Lifting Reduces Flow-Mediated Dilation in Nonathletes. Med Sci Sports Exerc. 2017 Apr;49(4):669-675.

Chen S, Andary M, Buschbacher R, Del Toro D, Smith B, So Y, Zimmermann K, Dillingham TR. Electrodiagnostic reference values for upper and lower limb nerve conduction studies in adult populations. Muscle Nerve. 2016 Sep;54(3):371-7.

Dillingham T, Chen S, Andary M, Buschbacher R, Del Toro D, Smith B, Zimmermann K, So Y. Establishing high-quality reference values for nerve conduction studies: A report from the normative data task force of the American Association Of Neuromuscular & Electrodiagnostic Medicine. Muscle Nerve. 2016 Sep;54(3):366-70.

Durand MJ, Zinkevich NS, Riedel M, Gutterman DD, Nasci VL, Salato VK, Hijjawi JB, Reuben CF, North PE, Beyer AM. Vascular Actions of Angiotensin 1-7 in the Human Microcirculation: Novel Role for Telomerase. Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1254-62.

Freed, J: Durand, M; Hoffmann, B; Densmore, J; Greene, A; Gutterman, D. Mitochondria-regulated formation of endothelial extracellular vesicles shifts the mediator of flow-induced vasodilation. Am J Physiol Heart Circ Physiol. 2017 Feb 17.

Gutterman DD, Chabowski DS, Kadlec AO, Durand MJ, Freed JK, Ait-Aissa K, Beyer AM The Human Microcirculation: Regulation of Flow and Beyond. Circ Res. 2016 Jan 8;118(1):157-72.

Krajnak K, Raju SG, Miller GR, Johnson C, Waugh S, Kashon ML, Riley DA. Long-term daily vibration exposure alters current perception threshold (CPT) sensitivity and myelinated axons in a rat-tail model of vibration-induced injury. J Toxicol Environ Health A. 2016;79(3):101-11.

Laine J, D'Souza A, Siddiqui S, Sayko O, Brazauskas R, Eickmeyer SM. Rehabilitation referrals and outcomes in the early period after hematopoietic cell transplantation. Bone Marrow Transplant. 2015 Oct;50(10):1352-7.

LaRoche AA, Nelson LD, Connelly PK, Walter KD, McCrea MA. Sport-Related Concussion Reporting and State Legislative Effects. Clin J Sport Med 2016 Jan;26(1):33-9.

Esquenazi A1, Alfaro A2, Ayyoub Z3, Charles D4, Dashtipour K5, Graham GD6, McGuire JR7, Odderson IR8, Patel AT9, Simpson DM10. OnabotulinumtoxinA for Lower Limb Spasticity: Guidance From a Delphi Panel Approach. PM R. 2017 Mar 7.

McGuire J, Heath K, O'Dell MW. Should Ultrasound Be Used Routinely to Guide Botulinum Toxin Injections for Spasticity? PM R. 2016 Oct;8(10):1004-1010.

Research Committees and Affiliations

Research Administration Committee (PM&R)
The RAC is composed of Department of Physical Medicine and Rehabilitation faculty. The RAC is under the direction of the Research Director. The department sets an annual budget to support research endeavors of faculty, fellows and residents. These funds will support pilot research proposals, attendance at national and regional meetings to present results of research and / or accept awards, and to provide assistance with publication costs.

Orthopedic Rehabilitation & Engineering Center (OREC)
The center was established in 1999 to facilitate research in support of the endeavors of the faculty, fellows, residents and graduate students participating in the programs of the MCW Departments of Orthopaedic Surgery and Physical Medicine and Rehabilitation and of the MU School of Dentistry and the MU Department of Biomedical Engineering.

The center brings together common threads within the disciplines of engineering, biomedical sciences, materials sciences, and clinical dentistry. The result is a unique environment for interdisciplinary applied research.

Human Motion Analysis Laboratory (Gait Lab)
The Department of Physical Medicine and Rehabilitation has collaborated with the Department of Orthopaedic Medicine and Marquette University to establish the Gait Lab. An agreement with the Gait Lab allows for the use of the facility without charge for resident research. Funded research budgets provide for financial support of the gait lab.

Rehabilitation Robotic Research and Design Lab (RRRD)
Established in 2004, the RRRD Lab is dedicated to the design, development and therapeutic use of novel, affordable, intelligent robotic / mechatronic and domotic assistants. It is affiliated with OREC and the Falk Neurorehabilitation Center at Marquette University.

The lab is focused on:

  • Examining underlying causes of upper limb impairment after neural disease, injury or cerebral accident.
  • Discovering effective methods to retrain functional recovery on daily living activities.
  • Developing new ways of facilitating independent living in daily living environments.

Contact Us

For more information on opportunities for collaboration, questions about research at the SRC, or questions on how to support research in PM&R.

Moriah Iverson, MS

Program Manager