Surgery

Publications

• Rho-related BTB Domain-containing Protein 1 Reverses Established Arterial Stiffness in Angiotensin II-treated Mice.

  (Fang S, Wu J, Reho J, Lu KT, Brozoski D, Werthman A, Kumar G, Silva SD, Muskus P, Wackman K, Mathison A, Urrutia RA, Teng BQ, Lin CW, Quelle FW, Sigmund CD.) FASEB J. 2022 May;36 Suppl 1 PMID: 35557171 SCOPUS ID: 2-s2.0-85130011716 05/14/2022

• To ChIP, or to CUT, that is the question: Comparative Evaluation of NextGen Methodologies for Studying the genome-wide distribution of Histone H3 Lysine 9 di-methyl mark in pancreatic cells.

  (Urrutia G, Abrudan JL, Du M, de Assuncao TM, Mathison AJ, Zimmermann MT, Lomberk G, Urrutia R.) FASEB J. 2022 May;36 Suppl 1 PMID: 35556470 SCOPUS ID: 2-s2.0-85130072518 05/14/2022

• Transcriptional Landscape Established by the Euchromatic Histone-lysine N-methyltransferase Pathway During Pancreas Ontogenesis and Pancreatitis.

  (Urrutia R, Salmonson A, Urrutia G, de Assuncao TM, Zimmermann MT, Mathison AJ, Lomberk G.) FASEB J. 2022 May;36 Suppl 1 PMID: 35556469 SCOPUS ID: 2-s2.0-85130010001 05/14/2022

• Defining the Mutational Landscape That Affects the Histone Demethylase KDM6A/UTX in Human Cancer.

  (Chi YI, Stodola TJ, de Assuncao TM, Volkman B, Smith B, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R.) FASEB J. 2022 May;36 Suppl 1 PMID: 35555661 SCOPUS ID: 2-s2.0-85130046941 05/14/2022

• Integrative Modeling, Molecular Mechanics, and Molecular Dynamics Evaluation of Genomics Variants in KMT2C (MLL3), a Gene Involved in Kleefstra Syndrome Type 2.

  (Jorge SD, Chi YI, de Assuncao TM, Mathison AJ, Volkman B, Smith B, Lomberk G, Zimmermann MT, Urrutia R.) FASEB J. 2022 May;36 Suppl 1 PMID: 35553749 SCOPUS ID: 2-s2.0-85130006059 05/14/2022

• Epigenomic mechanisms used by KrasG12D to regulate inflammatory gene clusters in epithelial pancreatic cancer cells, which are critical for reprogramming the tumor microenvironment.

  (Du M, Abrudan JL, Urrutia G, de Assuncao TM, Mathison AJ, Zimmermann MT, Lomberk G, Urrutia R.) FASEB J. 2022 May;36 Suppl 1 PMID: 35552230 SCOPUS ID: 2-s2.0-85130057842 05/14/2022

• Functional Inferences Derived from Defining the Interactome of H3K9me2 Writers and Readers

  (Pollin G, de Assuncao TM, Lomberk G, Urrutia R.) FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1 May 2022;36 PMID: 35552325 SCOPUS ID: 2-s2.0-85130026676 05/01/2022

• Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons.

  (Allison RL, Adelman JW, Abrudan J, Urrutia RA, Zimmermann MT, Mathison AJ, Ebert AD.) Genes (Basel). 2022 01 27;13(2) PMID: 35205286 PMCID: PMC8871895 SCOPUS ID: 2-s2.0-85124092767 02/26/2022

• Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers.

  (Chi YI, Stodola TJ, De Assuncao TM, Leverence EN, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R.) Comput Struct Biotechnol J. 2022;20:2200-2211 PMID: 35615018 PMCID: PMC9111933 SCOPUS ID: 2-s2.0-85130080827 05/27/2022

• Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons

  (Allison RL, Adelman JW, Abrudan J, Urrutia RA, Zimmermann MT, Mathison AJ, Ebert AD.) Genes. February 2022;13(2) SCOPUS ID: 2-s2.0-85124092767 02/01/2022

• Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics

  (Tripathi S, Dsouza NR, Mathison AJ, Leverence E, Urrutia R, Zimmermann MT.) Computational and Structural Biotechnology Journal. January 2022;20:117-127 SCOPUS ID: 2-s2.0-85121238740 01/01/2022

• KrasG12D induces changes in chromatin territories that differentially impact early nuclear reprogramming in pancreatic cells.

  (Mathison AJ, Kerketta R, de Assuncao TM, Leverence E, Zeighami A, Urrutia G, Stodola TJ, di Magliano MP, Iovanna JL, Zimmermann MT, Lomberk G, Urrutia R.) Genome Biol. 2021 10 14;22(1):289 PMID: 34649604 PMCID: PMC8518179 SCOPUS ID: 2-s2.0-85117299300 10/16/2021