Surgery

Publications

• Inorganic arsenic promotes luminal to basal transition and metastasis of breast cancer.

  (Danes JM, de Abreu ALP, Kerketta R, Huang Y, Palma FR, Gantner BN, Mathison AJ, Urrutia RA, Bonini MG.) FASEB J. 2020 Dec;34(12):16034-16048 PMID: 33047385 SCOPUS ID: 2-s2.0-85092336914 10/14/2020

• Variant anatomy of the biliary system as a cause of pancreatic and peri-ampullary cancers.

  (Muraki T, Reid MD, Pehlivanoglu B, Gonzalez RS, Sekhar A, Memis B, Xue Y, Cheng J, Jang KT, Mittal P, Cardona K, Kooby DA, Maithel S, Sarmiento JM, El-Rayes B, Lomberk G, Urrutia RA, Christians K, Tsai S, Evans DB, Adsay V.) HPB (Oxford). 2020 Dec;22(12):1675-1685 PMID: 32336556 SCOPUS ID: 2-s2.0-85083637358 04/28/2020

• The Promise of Circulating Tumor DNA (ctDNA) in the Management of Early-Stage Colon Cancer: A Critical Review.

  (Chakrabarti S, Xie H, Urrutia R, Mahipal A.) Cancers (Basel). 2020 09 29;12(10) PMID: 33003583 PMCID: PMC7601010 10/03/2020

• ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

  (Lan W, Santofimia-Castaño P, Swayden M, Xia Y, Zhou Z, Audebert S, Camoin L, Huang C, Peng L, Jiménez-Alesanco A, Velázquez-Campoy A, Abián O, Lomberk G, Urrutia R, Rizzuti B, Geli V, Soubeyran P, Neira JL, Iovanna J.) JCI Insight. 2020 Sep 17;5(18) PMID: 32780723 PMCID: PMC7526551 SCOPUS ID: 2-s2.0-85090785767 08/12/2020

• Targeting the CBP/β-Catenin Interaction to Suppress Activation of Cancer-Promoting Pancreatic Stellate Cells.

  (Che M, Kweon SM, Teo JL, Yuan YC, Melstrom LG, Waldron RT, Lugea A, Urrutia RA, Pandol SJ, Lai KKY.) Cancers (Basel). 2020 Jun 05;12(6) PMID: 32516943 PMCID: PMC7352534 06/11/2020

• Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature.

  (Yang C, Siebert JR, Burns R, Zheng Y, Mei A, Bonacci B, Wang D, Urrutia RA, Riese MJ, Rao S, Carlson KS, Thakar MS, Malarkannan S.) Elife. 2020 May 14;9 PMID: 32406817 PMCID: PMC7255804 SCOPUS ID: 2-s2.0-85085630468 05/15/2020

• Genetic variants in DGAT1 cause diverse clinical presentations of malnutrition through a specific molecular mechanism.

  (Gupta A, Dsouza NR, Zarate YA, Lombardo R, Hopkin R, Linehan AR, Simpson J, McCarrier J, Agre KE, Gavrilova RH, Stephens MC, Grothe RM, Monaghan KG, Xie Y, Basel D, Urrutia RA, Cole CR, Klee EW, Zimmermann MT.) Eur J Med Genet. 2020 Apr;63(4):103817 PMID: 31778854 SCOPUS ID: 2-s2.0-85076241133 11/30/2019

• Combined Targeting of G9a and Checkpoint Kinase 1 Synergistically Inhibits Pancreatic Cancer Cell Growth by Replication Fork Collapse.

  (Urrutia G, Salmonson A, Toro-Zapata J, de Assuncao TM, Mathison A, Dusetti N, Iovanna J, Urrutia R, Lomberk G.) Mol Cancer Res. 2020 03;18(3):448-462 PMID: 31822519 PMCID: PMC7056528 SCOPUS ID: 2-s2.0-85081130002 12/12/2019

• Motor Neuron Generation from iPSCs from Identical Twins Discordant for Amyotrophic Lateral Sclerosis.

  (Seminary ER, Santarriaga S, Wheeler L, Mejaki M, Abrudan J, Demos W, Zimmermann MT, Urrutia RA, Fee D, Barkhaus PE, Ebert AD.) Cells. 2020 02 28;9(3) PMID: 32121108 PMCID: PMC7140469 03/04/2020

• PAX1 is essential for development and function of the human thymus.

  (Yamazaki Y, Urrutia R, Franco LM, Giliani S, Zhang K, Alazami AM, Dobbs AK, Masneri S, Joshi A, Otaizo-Carrasquero F, Myers TG, Ganesan S, Bondioni MP, Ho ML, Marks C, Alajlan H, Mohammed RW, Zou F, Valencia CA, Filipovich AH, Facchetti F, Boisson B, Azzari C, Al-Saud BK, Al-Mousa H, Casanova JL, Abraham RS, Notarangelo LD.) Sci Immunol. 2020 02 28;5(44) PMID: 32111619 PMCID: PMC7189207 SCOPUS ID: 2-s2.0-85081071846 03/01/2020

• Discovery, expression, cellular localization, and molecular properties of a novel, alternative spliced HP1γ isoform, lacking the chromoshadow domain.

  (Mathison A, Milech De Assuncao T, Dsouza NR, Williams M, Zimmermann MT, Urrutia R, Lomberk G.) PLoS One. 2020;15(2):e0217452 PMID: 32027651 PMCID: PMC7004349 SCOPUS ID: 2-s2.0-85079081692 02/07/2020

• Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma.

  (Santofimia-Castaño P, Xia Y, Peng L, Velázquez-Campoy A, Abián O, Lan W, Lomberk G, Urrutia R, Rizzuti B, Soubeyran P, Neira JL, Iovanna J.) Cells. 2019 11 17;8(11) PMID: 31744261 PMCID: PMC6912534 SCOPUS ID: 2-s2.0-85082729502 11/21/2019