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Pritchard Research Laboratory

Located in the Children's Research Institute, 4th Floor

Lab dishes extration close up

Mission Statement

To reduce suffering and pain in children who have sickle cell disease and bronchopulmonary dysplasia.

 

Kirkwood A. Pritchard, Jr., PhD
Professor
Division of Pediatric Surgery
Department of Surgery
Medical College of Wisconsin

Research Areas

The primary research focus of the Pritchard lab is on vascular function in sickle cell disease and bronchopulmonary dysplasia. The lab discovered that sickle cell disease and bronchopulmonary dysplasia induce an inflammatory pathway that impairs vascular and lung function. In sickle cell disease, vascular dysfunction increases the risk of vasculopathy and vasocongestion that in turn increase the risk of vaso-occlusive crisis and stroke. In bronchopulmonary dysplasia, vascular and airway dysfunction impairs angiogenesis and airway maturation. Babies who have bronchopulmonary dysplasia are at greater risk of developing asthma-like airway disease and chronic obstructive pulmonary disease as they grow into adults.

Members of the Lab

Kirkwood A. Pritchard, Jr., PhD

Kirkwood A. Pritchard, Jr., PhD
Professor

Deron W. Jones, BA

Deron W. Jones, BA
Lab Manager

Keguo Li, PhD

Keguo Li, PhD
Research Scientist

Key Collaborators:

Ru-Jeng Teng, MD
Rashmi Sood, PhD
Kevin R. Rarick, PhD
Ganesh Konduri, MD

Supporting Funding List

  • NIH National Heart Lung and Blood Institute R01HL128371 (Mechanisms of Inflammation in Sickle Cell Disease)
  • NIH National Institute of Neurological Disorders and Stroke R21NS106451 (Trifunctional Peptides for Targeting the Ischemic Cascade)
  • NIH Small Business Innovation Research Program R43HL139171 (RENEUROGEN LLC subcontract; KYC Reduces Vasculopathy in Sickle Cell Disease)
  • Children’s Research Institute

Contact Us

Kirkwood A. Pritchard Jr., PhD
(414) 955-2215

Deron W. Jones, BA
Lab Manager
(414) 955-4612

Medical College of Wisconsin
Children’s Research Institute, 4th Floor
8701 Watertown Plank Rd.
Milwaukee, WI 53226


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