Designing the next generation of gene therapy treatments

GFP expression in the retinal vasculature The Ocular Gene Therapy Laboratory (OGTL) founded by Daniel M. Lipinski, DPhil, is dedicated to the development of novel therapies to prevent human blindness. Occupying >1,000 sq.ft. of research space within the Medical College of Wisconsin Eye Institute, OGTL provides the expertise and infrastructure to design the next generation of gene therapy treatments aimed at preventing retinal cell death or dysfunction.
OGTL News
Chris Reid Book Chapter
January 01, 2018

Publication - Chris Reid has a chapter published in the Methods in Molecular Biology Springer Protocols book series.

In his upcoming book chapter, Chris Reid, a final year graduate student in the Cell Biology program, describes an optimized methodology for producing and purifying recombinant adeno-associated virus (rAAV) vectors on two different scales, including a micro-scale preparation that can be used for high-throughput screening of novel serotypes and expression constructs.
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IOVS 12/2018
December 04, 2017

Publication – Chris Reid and Kristina Ertel have an article published in the journal Investigative Ophthalmology and Visual Science

Chris Reid, a final year graduate student in the IDP program, and Kristina Ertel, a former research technologist in the Ocular Gene Therapy Laboratory, recently published an article describing a recombinant adeno-associated virus vector with significantly improved photoreceptor targeting following intravitreal injection.
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Read the full article here

 
Emily Netteschem
July 10, 2017

Welcome – Emily Nettesheim joins OGTL as a Research Technologist

Emily Nettesheim, who recently received Bachelors degrees (BS) in both Anthropology and Molecular Biology from the University of Madison, Wisconsin, will join OGTL as a research Technologist.
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Upcoming Events
February 7, 2018 John Conto, OD, FAAO
“DEWSII: Ocular Surface Disease Update”
Grand Rounds
Medical College of Wisconsin
Milwaukee, WI, USA
February 17, 2018 Midwinter Retina Meeting
Ophthalmology and Visual Sciences at the Eye Institute, Medical College of Wisconsin
Milwaukee, WI, USA

March 6, 2018
(12:00 - 1:00pm)

PhD Thesis Defense
Christopher A. Reid
Eye Institute Lower Level Conference Room
Milwaukee, WI, USA

March 7, 2018 Eric Suhler, MD, MPH
“Biologic Warfare in Uveitis”
Grand Rounds
Medical College of Wisconsin
Milwaukee, WI, USA
March 12, 2018 Timothy S. Kern, PhD
“Photoreceptors and the development of diabetic retinopathy”
Distinguished Lecture Series
Medical College of Wisconsin
Milwaukee, WI, USA
April 4, 2018 Gerald Harris, MD
“Idiopathic Orbital Inflammation: A Pathogenetic Construct and Treatment Strategy for a Spectrum of Diseases”
Grand Rounds
Medical College of Wisconsin
Milwaukee, WI, USA
April 16, 2018 Janet Sparrow, PhD
“Shedding light on visual cycle adducts”
Distinguished Lecture Series
Medical College of Wisconsin
Milwaukee, WI, USA
April 29 – May 3, 2018 ARVO Annual Meeting
Honolulu, Hawaii, USA
May 2, 2018 Kenneth Wright, MD
“Extreme Strabismus”
Grand Rounds
Medical College of Wisconsin
Milwaukee, WI, USA
June 6, 2018 Kathryn Colby, MD, PhD
“Fuchs’ Dystrophy: Past, Present and Future”
Grand Rounds
Medical College of Wisconsin
Milwaukee, WI, USA

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