Aron Geurts, PhD
Associate Professor, Department of Physiology
Dr. Geurts is an Associate Professor in the Department of Physiology, Cardiovascular Research Center and Genomic Sciences and Precision Medicine Center. He leads an NIH-funded research team focused on innovating novel approaches to genetic engineering and creating animal and cell models of complex genetic human diseases. He is a recipient of a prestigious New Innovator award from the Office of the Director of the NIH.
My role in Dr. Aron Geurts' lab is to help facilitate the creation of genetically modified models. I design nuclease reagents that are then created and validated in the Geurts lab that will be used to create these modifications. I am also responsible for the day to day operations in the lab. My research interests are mainly molecular biology and technology and how to create and develop animal models.
Research Scientist II
My research interests are related to reproductive biology in rats. I am especially interested in assisted reproductive technology such as cryopreservation of gametes and zygotes, re-derivation and embryo manipulation. These technologies are reliable methods to preserve strains which were generated using new gene modification technologies such as Zinc Finger Nucleases (ZFNs) and TAL Effector Nucleases (TALENs), to avoid breeding problems. I am also interested in the development of more effective sperm cryopreservation and nuclear transfer technology.
Research Technologist III
Under Dr. Geurts I help coordinate the business conducted in the Rat Transgenic Service Center. I also perform micro-injections and sperm cryopreservation for the Service Center.
(Presa M, Racine JJ, Dwyer JR, Lamont DJ, Ratiu JJ, Sarsani VK, Chen YG, Geurts A, Schmitz I, Stearns T, Allocco J, Chapman HD, Serreze DV.) J Immunol. 2018 Oct 01;201(7):1907-1917.
(Xue H, Zhang G, Geurts AM, Usa K, Jensen DM, Liu Y, Widlansky ME, Liang M.) EBioMedicine. 2018 Sep;35:260-269.
(Liu Y, Usa K, Wang F, Liu P, Geurts AM, Li J, Williams AM, Regner KR, Kong Y, Liu H, Nie J, Liang M.) J Am Soc Nephrol. 2018 Oct;29(10):2518-2528.
(Spires D, Ilatovskaya DV, Levchenko V, North PE, Geurts AM, Palygin O, Staruschenko A.) Am J Physiol Renal Physiol. 2018 Oct 01;315(4):F1091-F1097.
(Siebers EM, Choi MJ, Tinklenberg JA, Beatka MJ, Ayres S, Meng H, Helbling DC, Takizawa A, Bennett B, Garces AM, Dias Duarte Machado LG, Dimmock D, Dwinell MR, Geurts AM, Lawlor MW.) J Neuropathol Exp Neurol. 2018 Aug 01;77(8):665-672.
(Ilatovskaya DV, Blass G, Palygin O, Levchenko V, Pavlov TS, Grzybowski MN, Winsor K, Shuyskiy LS, Geurts AM, Cowley AW Jr, Birnbaumer L, Staruschenko A.) J Am Soc Nephrol. 2018 Jul;29(7):1917-1927.
(Stodola TJ, Liu P, Liu Y, Vallejos AK, Geurts AM, Greene AS, Liang M.) Physiol Genomics. 2018 May 01;50(5):323-331.
(Prokop JW, Yeo NC, Ottmann C, Chhetri SB, Florus KL, Ross EJ, Sosonkina N, Link BA, Freedman BI, Coppola CJ, McDermott-Roe C, Leysen S, Milroy LG, Meijer FA, Geurts AM, Rauscher FJ 3rd, Ramaker R, Flister MJ, Jacob HJ, Mendenhall EM, Lazar J.) J Am Soc Nephrol. 2018 May;29(5):1525-1535.
(Widlansky ME, Jensen DM, Wang J, Liu Y, Geurts AM, Kriegel AJ, Liu P, Ying R, Zhang G, Casati M, Chu C, Malik M, Branum A, Tanner MJ, Tyagi S, Usa K, Liang M.) EMBO Mol Med. 2018 03;10(3).
(Moehring F, Cowie AM, Menzel AD, Weyer AD, Grzybowski M, Arzua T, Geurts AM, Palygin O, Stucky CL.) Elife. 2018 01 16;7.
(Mendiara I, Domeño C, Nerín C, Geurts AM, Osada J, Martínez-Beamonte R.) J Pharm Biomed Anal. 2018 Feb 20;150:396-405.
(Lukaszewicz KM, Durand MJ, Priestley JRC, Schmidt JR, Allen LA, Geurts AM, Lombard JH.) J Vis Exp. 2017 12 05(130).