Ivor Benjamin Lab
Dr. Benjamin has been a champion by providing leadership to broaden the global reach of biomedical research in efforts to reduce death and disability from cardiovascular diseases, stroke and other brain disorders.
He is a primary investigator for other major cardiovascular research projects including a $4 million award funded by the Advancing a Healthier Wisconsin Endowment. Recently, he completed his term as president of the Association of University Cardiologists and is now serving a year-long tenure as the American Heart Association’s 82nd president.
CVC In The News
Dr. Ivor Benjamin onstage at Apple product launch
Watch Dr. Benjamin introduce new functionality that provides the ability for people to access health data from an on-demand Electrocardiogram (ECG).
The State of Heart Research
Milwaukee's NPR radio program Lake Effect speaks with Ivor Benjamin, MD, Director of the MCW Cardiovascular Center about the state of cardiovascular research and the national push to train the general population in CPR and the use of automated external defibrillators (AEDs).
Ivor Benjamin, MD, FAHA, FACC
Director, Cardiovascular Center
Professor, Medicine, Physiology, Pharmacology and Toxicology, Cell Biology, Neurobiology and Anatomy, and Surgery
Froedtert & Medical College of Wisconsin
ibenjamin@mcw.edu
Dr. Ivor Benjamin is the Director of the Cardiovascular Center, co-director of the NIH T32 Postdoctoral Fellowship in Cardiovascular Sciences and co-leader of the CVC’s Signature Program in Precision Cardiovascular Medicine. He is a Professor of Medicine, Physiology, Pharmacology & Toxicology, Cell Biology, Neurobiology & Anatomy, and Surgery at the Medical College of Wisconsin. Dr. Benjamin earned his MD from the Johns Hopkins University School of Medicine, internship and residency in Internal Medicine at Yale University School of Medicine, and received fellowship training in clinical cardiology, molecular cardiology, and molecular biology at Michael Reese Hospital (University of Chicago), Duke University Medical Center, and The University of Texas Southwestern Medical Center at Dallas. A certified specialist and consultant in internal medicine and cardiology, his clinical interests are general cardiology, inheritable heart failure, and myocardial infarction. His research focuses on genes encoding heat shock proteins and oxido-reductive stress response pathways of direct relevance to genetic forms of heart disease, cardiotoxicological science and precision medicine.
An Established Investigator of the American Heart Association, Dr. Benjamin’s longstanding and distinguished career as a physician scientist has taken him across the country, including 10 years at the University of Utah School of Medicine where he was named the Division Chief of Cardiology and the Christi T. Smith Endowed Chair of Cardiovascular Medicine. He is the recipient of countless honors including the Award of Merit from the American Heart Association, the Daniel Savage Memorial Service Award from the Association of Black Cardiologists, and the prestigious NIH Director's Pioneer Award from the National Heart, Lung, and Blood Institute. He serves as Editor-in-Chief of Cecil Essential of Medicine 9th Edition and has authored over 130 books, book chapters and scientific papers. Dr. Benjamin is a founding member of the Journal of the American Heart Association, and he currently serves on the editorial boards of Circulation and Circulation Research.
Qiang Dai, PhD
Research Associate II
qdai@mcw.edu
Our laboratory has longstanding interests in the role that stress response (HSF/HSP) pathways play in the development, progression, and, ultimately, the prevention of acquired and inheritable cardiac diseases. My studies of genetically engineered mouse models and somatic cell cultures are exploring the mechanisms underlying the effects of genetic, metabolic (e.g., redox), and other perturbations in ischemic cardioprotection and heart failure.
Elizabeth Schibly
Shuping Lai, PhD
Research Associate II
slai@mcw.edu
My research project aims on modeling cardiac diseases in a culture dish by utilizing patient specimens. We are creating cardiomyocytes from human induced pluripotent stem cells, differentiate them into cardiomyocytes and use them as a means to mimic the disease in a dish. My major interests are drug-screenings and biochemical assays to exhibit different susceptibilities of cardiac cells to cardiac drugs, to predict adverse drug responses more accurately and to find best suitable drugs for cardiac diseases.
Recent Publications
-
Protecting Medical Trainees on the COVID-19 Frontlines Saves Us All.
(Harrington RA, Elkind MSV, Benjamin IJ.) Circulation. 2020 May 05;141(18):e775-e777 PMID: 32250654 PMCID: PMC7176273 04/07/2020
-
The Role of the American Heart Association in the Global COVID-19 Pandemic.
(Elkind MSV, Harrington RA, Benjamin IJ.) Circulation. 2020 04 14;141(15):e743-e745 PMID: 32181680 PMCID: PMC7172571 03/18/2020
-
(Warner JJ, Benjamin IJ, Churchwell K, Firestone G, Gardner TJ, Johnson JC, Ng-Osorio J, Rodriguez CJ, Todman L, Yaffe K, Yancy CW, Harrington RA, American Heart Association Advocacy Coordinating Committee.) Circulation. 2020 03 10;141(10):e601-e614 PMID: 32008369 02/06/2020
-
(McDermott-Roe C, Lv W, Maximova T, Wada S, Bukowy J, Marquez M, Lai S, Shehu A, Benjamin I, Geurts A, Musunuru K.) JCI Insight. 2019 11 14;4(22) PMID: 31723063 PMCID: PMC6948852 SCOPUS ID: 2-s2.0-85077370393 11/15/2019
-
Fixed-dose combination antihypertensive medications.
(Benjamin IJ, Kreutz R, Olsen MH, Schutte AE, Lopez-Jaramillo P, Frieden TR, Sliwa K, Lackland DT, Brainin M.) Lancet. 2019 08 24;394(10199):637-638 PMID: 31320200 07/20/2019
-
(Ma X, Mani K, Liu H, Kovacs A, Murphy JT, Foroughi L, French BA, Weinheimer CJ, Kraja A, Benjamin IJ, Hill JA, Javaheri A, Diwan A.) J Am Heart Assoc. 2019 02 19;8(4):e010866 PMID: 30773991 PMCID: PMC6405666 SCOPUS ID: 2-s2.0-85061707716 02/19/2019
-
Fixed-dose combination antihypertensive medications
(Ivor J. Benjamin, Reinhold Kreutz, Michael H. Olsen, Aletta E. Schutte, Patricio Lopez-Jaramillo; *Thomas R. Freiden, Karen Sliwa, Daniel T. Lackland, Michael Brainin.) The Lancet Global Health. 07/15/2019
-
(Wiegers SE, Ryan T, Arrighi JA, Brown SM, Canaday B, Damp JB, Diaz-Gomez JL, Figueredo VM, Garcia MJ, Gillam LD, Griffin BP, Kirkpatrick JN, Klarich KW, Lui GK, Maffett S, Naqvi TZ, Patel AR, Poulin MF, Rose GA, Swaminathan M, Mendes LA, Adams JE, Brush JE, Dec GW, Denktas A, Fernandes S, Freeman R, Hahn RT, Halperin JL, Housholder-Hughes SD, Khan SS, Lin CH, Marine JE, McPherson JA, Niazi K, Ryan T, Solomon MA, Spicer RL, Tam M, Wang A, Weissman G, Weitz HH, Williams ES, Valentine CM, Attebery TW, Oetgen WJ, Phoubandith DR, Callahan TV, Scholtz A, Benjamin I, Brown N, Robertson RM, Lindner J, Wiegerink R, LaFluria C.) Circulation: Cardiovascular Imaging. 1 July 2019;12(7) SCOPUS ID: 2-s2.0-85073589978 07/01/2019
-
Global Improvement of Accuracy Standards for Devices that Measure Blood Pressure
(Corresponding Author: James SharmanrnCo-Authors: Eoin O’Brien; Bruce Alpert; Aletta Schutte; Christian Delles; Michael Hecht-Olsen; Roland Asmar; Neil Atkins; Eduardo Barbosa; David Calhoun; Norm Campbell; John Chalmers; Ivor Benjamin; Garry Jennings; Stephane Laurent; Pierre Boutouyrie; Patricio Lopez-Jaramillo; Richard McManus; Anastasia Mihailidou; Pedro Ordunez; Raj Padwal; Paolo Palatini; Gianfranco Parati; Neil Poulter; Michael Rakotz; Clive Rosendorff; Francesca Saladini; Angelo Scuteri; Weimar Sebba Barroso; Myeong-Chan Cho; Ki-Chul Sung; Raymond Townsend; Ji-Guang Wang; Tine Willum Hansen; Gregory Wozniak; George Stergiournrn.) The Lancet Global Health. 04/24/2019
-
Wearable devices transform cardiac care and treatment
(Oujiri, James, MD; Benjamin, Ivor, MD.) Milwaukee Journal Sentinel. 02/27/2019
-
Cooperative interaction among BMAL1, HSF1, and p53 protects mammalian cells from UV stress.
(Kawamura G, Hattori M, Takamatsu K, Tsukada T, Ninomiya Y, Benjamin I, Sassone-Corsi P, Ozawa T, Tamaru T.) Commun Biol. 2018;1:204 PMID: 30480104 PMCID: PMC6250677 SCOPUS ID: 2-s2.0-85066236743 11/28/2018
-
(Gabai VL, Meng L, Kim G, Mills TA, Benjamin IJ, Sherman MY.) Mol Cell Biol. 2017 10 15;37(20) PMID: 28951485 PMCID: PMC5615190 SCOPUS ID: 2-s2.0-85030103199 09/28/2017