Ivor Benjamin Lab
Dr. Benjamin has been a champion by providing leadership to broaden the global reach of biomedical research in efforts to reduce death and disability from cardiovascular diseases, stroke and other brain disorders.
He is a primary investigator for other major cardiovascular research projects including a $4 million award funded by the Advancing a Healthier Wisconsin Endowment. Recently, he completed his term as president of the Association of University Cardiologists and is now serving a year-long tenure as the American Heart Association’s 82nd president.
CVC In The News
Dr. Ivor Benjamin onstage at Apple product launch
Watch Dr. Benjamin introduce new functionality that provides the ability for people to access health data from an on-demand Electrocardiogram (ECG).
The State of Heart Research
Milwaukee's NPR radio program Lake Effect speaks with Ivor Benjamin, MD, Director of the MCW Cardiovascular Center about the state of cardiovascular research and the national push to train the general population in CPR and the use of automated external defibrillators (AEDs).
Ivor Benjamin, MD, FAHA, FACC
Director, Cardiovascular Center
Professor, Medicine, Physiology, Pharmacology and Toxicology, Cell Biology, Neurobiology and Anatomy, and Surgery
Froedtert & the Medical College of Wisconsin
Dr. Ivor Benjamin is the Director of the Cardiovascular Center, co-director of the NIH T32 Postdoctoral Fellowship in Cardiovascular Sciences and co-leader of the CVC’s Signature Program in Precision Cardiovascular Medicine. He is a Professor of Medicine, Physiology, Pharmacology & Toxicology, Cell Biology, Neurobiology & Anatomy, and Surgery at the Medical College of Wisconsin. Dr. Benjamin earned his MD from the Johns Hopkins University School of Medicine, internship and residency in Internal Medicine at Yale University School of Medicine, and received fellowship training in clinical cardiology, molecular cardiology, and molecular biology at Michael Reese Hospital (University of Chicago), Duke University Medical Center, and The University of Texas Southwestern Medical Center at Dallas. A certified specialist and consultant in internal medicine and cardiology, his clinical interests are general cardiology, inheritable heart failure, and myocardial infarction. His research focuses on genes encoding heat shock proteins and oxido-reductive stress response pathways of direct relevance to genetic forms of heart disease, cardiotoxicological science and precision medicine.
An Established Investigator of the American Heart Association, Dr. Benjamin’s longstanding and distinguished career as a physician scientist has taken him across the country, including 10 years at the University of Utah School of Medicine where he was named the Division Chief of Cardiology and the Christi T. Smith Endowed Chair of Cardiovascular Medicine. He is the recipient of countless honors including the Award of Merit from the American Heart Association, the Daniel Savage Memorial Service Award from the Association of Black Cardiologists, and the prestigious NIH Director's Pioneer Award from the National Heart, Lung, and Blood Institute. He serves as Editor-in-Chief of Cecil Essential of Medicine 9th Edition and has authored over 130 books, book chapters and scientific papers. Dr. Benjamin is a founding member of the Journal of the American Heart Association, and he currently serves on the editorial boards of Circulation and Circulation Research.
Qiang Dai, PhD
Research Associate II
Our laboratory has longstanding interests in the role that stress response (HSF/HSP) pathways play in the development, progression, and, ultimately, the prevention of acquired and inheritable cardiac diseases. My studies of genetically engineered mouse models and somatic cell cultures are exploring the mechanisms underlying the effects of genetic, metabolic (e.g., redox), and other perturbations in ischemic cardioprotection and heart failure.
Shuping Lai, PhD
Research Associate II
My research project aims on modeling cardiac diseases in a culture dish by utilizing patient specimens. We are creating cardiomyocytes from human induced pluripotent stem cells, differentiate them into cardiomyocytes and use them as a means to mimic the disease in a dish. My major interests are drug-screenings and biochemical assays to exhibit different susceptibilities of cardiac cells to cardiac drugs, to predict adverse drug responses more accurately and to find best suitable drugs for cardiac diseases.
- Melinda Choi | Second-Year Medical Student (MSII), Medical College of Wisconsin
- Kurt Kolander
- Katie Mitzelfelt, PhD | Postdoctoral Fellow, University of Washington, Dr. Chuck Murry's Laboratory
- Mai Thao, PhD | Senior Chemist, Medtronic
(Sanyahumbi A, Ali S, Benjamin IJ, Karthikeyan G, Okello E, Sable CA, Taubert K, Wyber R, Zuhlke L, Carapetis JR, Beaton AZ, American Heart Association.) J Am Heart Assoc. 2022 03;11(5):e024517 PMID: 35049336 PMCID: PMC9075066 01/21/2022
(McNally EM, Elkind MSV, Benjamin IJ, Chung MK, Dillon GH, Hernandez AF, Ibeh C, Lloyd-Jones DM, McCullough LD, Wold LE, Wright DR, Wu JC.) Circulation. 2021 12 07;144(23):e461-e471 PMID: 34719260 SCOPUS ID: 2-s2.0-85122546616 11/02/2021
(Coombs GS, Rios-Monterrosa JL, Lai S, Dai Q, Goll AC, Ketterer MR, Valdes MF, Uche N, Benjamin IJ, Wallrath LL.) Redox Biol. 2021 Nov 25;48:102196 PMID: 34872044 PMCID: PMC8646998 12/07/2021
(Hateley S, Lopez-Izquierdo A, Jou CJ, Cho S, Schraiber JG, Song S, Maguire CT, Torres N, Riedel M, Bowles NE, Arrington CB, Kennedy BJ, Etheridge SP, Lai S, Pribble C, Meyers L, Lundahl D, Byrnes J, Granka JM, Kauffman CA, Lemmon G, Boyden S, Scott Watkins W, Karren MA, Knight S, Brent Muhlestein J, Carlquist JF, Anderson JL, Chahine KG, Shah KU, Ball CA, Benjamin IJ, Yandell M, Tristani-Firouzi M.) Nat Commun. 2021 11 08;12(1):6442 PMID: 34750360 PMCID: PMC8575962 11/10/2021
(Dai W, Lund H, Chen Y, Zhang J, Osinski K, Jones SZ, Kreuziger LB, L??pez JA, Benjamin IJ, Silverstein RL, Zheng Z.) J Clin Lipidol. 2021 Sep-Oct;15(5):724-731 PMID: 34470719 PMCID: PMC8353976 SCOPUS ID: 2-s2.0-85114047849 09/03/2021
(Chow SL, Sasson C, Benjamin IJ, Califf RM, Compton WM, Oliva EM, Robson C, Sanchez EJ.) Circulation. 2021 09 28;144(13):e218-e232 PMID: 34407637 SCOPUS ID: 2-s2.0-85116553125 08/20/2021
(Puzyrenko A, Jacobs ER, Sun Y, Felix JC, Sheinin Y, Ge L, Lai S, Dai Q, Gantner BN, Nanchal R, North PE, Simpson PM, Rui H, Benjamin IJ.) Cell Stress Chaperones. 2021 09;26(5):859-868 PMID: 34382151 PMCID: PMC8357488 SCOPUS ID: 2-s2.0-85112285201 08/13/2021
(Executive Committee, Benjamin IJ, Valentine CM, Oetgen WJ, Sheehan KA, Task Force 1, Brindis RG, Roach WH Jr, Harrington RA, Levine GN, Redberg RF, Broccolo BM, Hernandez AF, Task Force 2, Douglas PS, Pi??a IL, Benjamin EJ, Coylewright MJ, Saucedo JF, Ferdinand KC, Hayes SN, Poppas A, Task Force 3, Furie KL, Mehta LS, Erwin JP 3rd, Mieres JH, Murphy DJ Jr, Weissman G, West CP, Task Force 4, Lawrence WE Jr, Masoudi FA, Jones CP, Matlock DD, Miller JE, Spertus JA, Todman L, Task Force 5, Biga C, Chazal RA, Creager MA, Fry ET, Mack MJ, Yancy CW, Anderson RE.) J Am Coll Cardiol. 2021 06 22;77(24):3079-3133 PMID: 33994057 PMCID: PMC8091280 05/18/2021
(Benjamin IJ.) J Clin Invest. 2021 05 03;131(9) PMID: 33938451 PMCID: PMC8087192 SCOPUS ID: 2-s2.0-85105277080 05/04/2021
(Pant T, Dhanasekaran A, Zhao M, Thorp EB, Forbess JM, Bosnjak ZJ, Benjamin IJ, Ge ZD.) Sci Rep. 2021 01 28;11(1):2571 PMID: 33510471 PMCID: PMC7843621 SCOPUS ID: 2-s2.0-85100002752 01/30/2021
(Coombs GS, Rios-Monterrosa JL, Lai S, Dai Q, Goll AC, Ketterer MR, Valdes MF, Uche N, Benjamin IJ, Wallrath LL.) Redox Biology. December 2021;48 SCOPUS ID: 2-s2.0-85120438753 12/01/2021